scholarly journals Synthesis and evaluation of bis(imino)anthracene derivatives as G-quadruplex ligands

2021 ◽  
Author(s):  
Tomris Coban ◽  
Cameron Robertson ◽  
Sianne Schwikkard ◽  
Richard Singer ◽  
Adam LeGresley
Keyword(s):  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
G Quadruplex ◽  
Anthracene Derivatives ◽  
Line P ◽  
Oligonucleotide Sequence

The synthesis of a small number of bis(imino)anthracene derivatives is reported. They were evaluated via NMR for binding efficacy to the G-quadruplex-forming oligonucleotide sequence (TTGGGTT) and show activity against the HeLa cancer cell line.

HTS-FTIR spectroscopy allows the classification of polyphenols according to their differential effects on the MDA-MB-231 breast cancer cell line

The Analyst ◽  
2017 ◽  
Vol 142 (8) ◽  
pp. 1244-1257 ◽  
Author(s):  
A. Mignolet ◽  
V. Mathieu ◽  
E. Goormaghtigh
Keyword(s):  
Breast Cancer ◽  
Ftir Spectroscopy ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Differential Effects ◽  
Line P

FTIR-based classification of the effect of polyphenols on a breast cancer cell line.

The biosynthesis of a graphene oxide-based zinc oxide nanocomposite using Dalbergia latifolia leaf extract and its biological applications

2020 ◽  
Vol 44 (5) ◽  
pp. 2166-2179 ◽  
Author(s):  
Elavarasan Nagaraj ◽  
Prakash Shanmugam ◽  
Kokila Karuppannan ◽  
Thirunavukkarasu Chinnasamy ◽  
Sujatha Venugopal
Keyword(s):  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Antibacterial Activities ◽  
Lung Cancer Cell Line ◽  
Lung Cancer Cell ◽  
A549 Lung Cancer Cell ◽  
Line P ◽  
A549 Lung ◽  
Mcf 7

ZnO/GO nanocomposites were synthesized and their antibacterial activities assessed against various pathogens. They are potential antibacterial materials and significant anticancer activity against the MCF-7 breast cancer cell line compared to the A549 lung cancer cell line.

scholarly journals Novel pH-sensitive and biodegradable micelles for the combined delivery of doxorubicin and conferone to induce apoptosis in MDA-MB-231 breast cancer cell line

RSC Advances ◽  
2020 ◽  
Vol 10 (49) ◽  
pp. 29228-29246 ◽  
Author(s):  
Akram Rahmani ◽  
Hassan Zavvar Mousavi ◽  
Roya Salehi ◽  
Ahmad Bagheri
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Chemotherapy ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Ph Sensitive ◽  
Line P

pH-sensitive micelles are desirable for co-drug delivery in cancer chemotherapy.

scholarly journals A naphthalene diimide G-quadruplex ligand inhibits cell growth and down-regulates BCL-2 expression in an imatinib-resistant gastrointestinal cancer cell line

2018 ◽  
Vol 26 (11) ◽  
pp. 2958-2964 ◽  
Author(s):  
Mekala Gunaratnam ◽  
Gavin W. Collie ◽  
Anthony P. Reszka ◽  
Alan K. Todd ◽  
Gary N. Parkinson ◽  
...  
Keyword(s):  
Cell Growth ◽  
Cell Line ◽  
Cancer Cell ◽  
Gastrointestinal Cancer ◽  
Cancer Cell Line ◽  
Naphthalene Diimide ◽  
Imatinib Resistant ◽  
G Quadruplex

Dual-targeting organometallic ruthenium(ii) anticancer complexes bearing EGFR-inhibiting 4-anilinoquinazoline ligands

2015 ◽  
Vol 44 (29) ◽  
pp. 13100-13111 ◽  
Author(s):  
Yang Zhang ◽  
Wei Zheng ◽  
Qun Luo ◽  
Yao Zhao ◽  
Erlong Zhang ◽  
...  
Keyword(s):  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Dual Targeting ◽  
Anticancer Complexes ◽  
Line P

Organoruthenium complexes containing 4-anilinoquinazolines show dual-targeting activity, and highly inhibit the growth of the HeLa cancer cell line.

ATR-FTIR spectroscopy shows changes in ovarian cancer cells after incubation with novel organoamidoplatinum(ii) complexes

The Analyst ◽  
2018 ◽  
Vol 143 (24) ◽  
pp. 6087-6094 ◽  
Author(s):  
Khansa Al-Jorani ◽  
Anja Rüther ◽  
Rukshani Haputhanthri ◽  
Glen B. Deacon ◽  
Hsiu Lin Li ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Ftir Spectroscopy ◽  
Cancer Cells ◽  
Cell Line ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Ovarian Cancer Cell Line ◽  
Cancer Cell Line ◽  
Ovarian Cancer Cells ◽  
Line P

ATR-FTIR spectroscopy has been applied to compare the effect of new organoamidoplatinum(ii) complexes with cisplatin on cells from a cisplatin-sensitive and a cisplatin-resistant ovarian cancer cell line.

scholarly journals The tetrameric peptide LfcinB (20–25)4 derived from bovine lactoferricin induces apoptosis in the MCF-7 breast cancer cell line

RSC Advances ◽  
2019 ◽  
Vol 9 (36) ◽  
pp. 20497-20504 ◽  
Author(s):  
Jorge Rodríguez Guerra ◽  
Andrea Barragán Cárdenas ◽  
Alejandra Ochoa-Zarzosa ◽  
Joel López Meza ◽  
Adriana Umaña Pérez ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cytotoxic Effect ◽  
Cancer Cell Line ◽  
Bovine Lactoferricin ◽  
Line P ◽  
Mcf 7

The cytotoxic effect of the tetrameric peptide LfcinB (20–25)4 against breast cancer cell line ATCC® HTB-22™ (MCF-7) was evaluated.

scholarly journals Natural tripeptide capped pH-sensitive gold nanoparticles for efficacious doxorubicin delivery both in vitro and in vivo

Nanoscale ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 1067-1074 ◽  
Author(s):  
Krishan Kumar ◽  
Parikshit Moitra ◽  
Mohsin Bashir ◽  
Paturu Kondaiah ◽  
Santanu Bhattacharya
Keyword(s):  
Gold Nanoparticles ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Ph Sensitive ◽  
Drug Resistant ◽  
Ph Responsive ◽  
Line P

AuNPs capped with a natural pH-responsive short tripeptide sequence are presented herein for the successful delivery of doxorubicin both in vitro and in vivo. Efficacy of the system has also been evaluated in drug resistant cancer cell line.

Synthesis and photodynamic activities of novel silicon(iv) phthalocyanines axially substituted with water soluble groups against HeLa cancer cell line

2021 ◽  
Vol 50 (7) ◽  
pp. 2570-2584
Author(s):  
Meltem Göksel ◽  
Mahmut Durmuş ◽  
Zekeriya Biyiklioglu
Keyword(s):  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Water Soluble ◽  
Soluble Groups ◽  
Line P

In this study, compounds 1 and 2 and their silicon(iv) phthalocyanine (SiPc) derivatives 3 and 4, which bear these ligands as substituents on the axial positions, were synthesized.

scholarly journals Synthesis of gallotannin capped iron oxide nanoparticles and their broad spectrum biological applications

RSC Advances ◽  
2021 ◽  
Vol 11 (17) ◽  
pp. 9880-9893
Author(s):  
Bilal Ahmed ◽  
Asad Syed ◽  
Khursheed Ali ◽  
Abdallah M. Elgorban ◽  
Afroz Khan ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Cell Line ◽  
Cancer Cell ◽  
Broad Spectrum ◽  
Biological Effects ◽  
Cancer Cell Line ◽  
Oxide Nanoparticles ◽  
Biological Applications ◽  
Planktonic Bacteria ◽  
Line P

Broad-spectrum biological effects of gallo-tannin capped Fe2O3 nanoparticles against planktonic bacteria, biofilm, fungi, and cancer cell line.

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