Design, synthesis, and biological evaluation of pyrazole-linked aloe emodin derivatives as potential anticancer agents

2021 ◽  
Author(s):  
Guddeti Dileep Kumar ◽  
Bandi Siva ◽  
Sravanthi Vadlamudi ◽  
Surendar Reddy Bathula ◽  
Hashnu Dutta ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Anticancer Activity ◽  
Cell Lines ◽  
Anticancer Agents ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Lead Compounds ◽  
Traditional Medicinal Plants ◽  
Aloe Emodin ◽  
Synthesis And Biological Evaluation

In connection with our continuous efforts to generate new derivatives from lead compounds isolated from traditional medicinal plants, a series of aloe-emodin derivatives were synthesized and assessed for potential anticancer activity against a panel of cancer cell lines.

Design, Synthesis and Biological Evaluation of Tetrahydrodibenzo[b,g][1,8]napthyridinones as Potential Anticancer Agents and Novel Aurora Kinases Inhibitors

2021 ◽  
Vol 6 (14) ◽  
pp. 3444-3452
Author(s):  
Asha V. Chate ◽  
Pramod A. Tagad ◽  
Giribala M. Bondle ◽  
Aniket P. Sarkate ◽  
Shailee V. Tiwari ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Aurora Kinases ◽  
Synthesis And Biological Evaluation

Design, Synthesis, and Biological Evaluation of (E)-Styrylbenzylsulfones as Novel Anticancer Agents

2008 ◽  
Vol 51 (1) ◽  
pp. 86-100 ◽  
Author(s):  
M. V. Ramana Reddy ◽  
Muralidhar R. Mallireddigari ◽  
Stephen C. Cosenza ◽  
Venkat R. Pallela ◽  
Nabisa M. Iqbal ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

Design, synthesis and biological evaluation of tetrazole-containing RXRα ligands as anticancer agents

2019 ◽  
Vol 164 ◽  
pp. 562-575 ◽  
Author(s):  
Zhiqiang Yan ◽  
Shuyi Chong ◽  
Huiyun Lin ◽  
Qian Yang ◽  
Xin Wang ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

scholarly journals Design, synthesis and biological evaluation of imidazopyridine–propenone conjugates as potent tubulin inhibitors

MedChemComm ◽  
2017 ◽  
Vol 8 (5) ◽  
pp. 1000-1006 ◽  
Author(s):  
Ibrahim Bin Sayeed ◽  
V. Lakshma Nayak ◽  
Mohd Adil Shareef ◽  
Neeraj Kumar Chouhan ◽  
Ahmed Kamal
Keyword(s):  
Antitumor Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Biological Evaluation ◽  
Human Cancer Cell ◽  
Design Synthesis ◽  
Human Cancer Cell Lines ◽  
Tubulin Inhibitors ◽  
Synthesis And Biological Evaluation

A library of imidazopyridine–propenone conjugates (8a–8u) were synthesized and evaluated for their antitumor activity against four human cancer cell lines.

scholarly journals Design, synthesis and biological evaluation of a novel class of anticancer agents: Anthracenylisoxazole lexitropsin conjugates

2009 ◽  
Vol 17 (4) ◽  
pp. 1671-1680 ◽  
Author(s):  
Xiaochun Han ◽  
Chun Li ◽  
Michael D. Mosher ◽  
Kevin C. Rider ◽  
Peiwen Zhou ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation
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