scholarly journals 4-Nitrophenyl activated esters are superior synthons for indirect radiofluorination of biomolecules

2020 ◽  
Vol 11 (8) ◽  
pp. 919-922
Author(s):  
Mohammad B. Haskali ◽  
Ashleigh L. Farnsworth ◽  
Peter D. Roselt ◽  
Craig A. Hutton

A comparative study of PNP- and TFP-activated esters of radiolabelled prosthetic groups demonstrates the superiority of PNP esters in terms of stability and yields for use in one-step radiolabelling of small molecules and peptides.

2015 ◽  
Vol 7 (49) ◽  
pp. 27106-27114 ◽  
Author(s):  
Wei Li ◽  
Daojuan Wang ◽  
Suhao Wang ◽  
Wei Ma ◽  
Svante Hedström ◽  
...  

2010 ◽  
Vol 12 (4) ◽  
pp. 286-290 ◽  
Author(s):  
Alexander D. Bennett ◽  
Catriona M. MacPhail ◽  
Debra S. Gibbons ◽  
Michael R. Lappin

Retention of tablets or capsules in the feline esophagus can be associated with esophagitis and esophageal stricture formation. The objective of this study was to evaluate the esophageal passage of tablets and capsules when administered with either a one-step pill gun with flavored liquid (FlavoRx pill glide) or a pill delivery treat (Pill Pockets). Four different medication administrations were evaluated on different days in eight normal cats: tablets with FlavoRx pill glide (T-FG), tablets with pill delivery treats (T-PP), capsules with FlavoRx pill glide (C-FG) and capsules with pill delivery treats (C-PP). The estimated average transit time was 36 s for T-FG, 60 s for T-PP, 16 s for C-FG, and 24 s for C-PP. The results of this study suggest that either pill delivery method is acceptable for successful passage of tablets or capsules into the stomach of cats using a single replicate.


2015 ◽  
Vol 19 (7) ◽  
pp. 488-493
Author(s):  
G. Kartopu ◽  
M. Crozier ◽  
A. Brunton ◽  
V. Barrioz ◽  
S. Hodgson ◽  
...  
Keyword(s):  

Author(s):  
Kanna Mori ◽  
Kaori Sakurai

Clickable photoreactive gold nanoparticles have been developed to facilitate one-step preparation of photoaffinity probes for bioactive small molecules and their application to target protein analysis.


2005 ◽  
Vol 109 (37) ◽  
pp. 8348-8355 ◽  
Author(s):  
Virginie Lemierre ◽  
Anna Chrostowska ◽  
Alain Dargelos ◽  
Henry Chermette

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