Effect of heparin and peptide conjugation on structure and functional properties of alginate in solutions and hydrogels

Materials Advances ◽

10.1039/d0ma00669f ◽

2021 ◽

Author(s):

Nir Goldberg ◽

Yulia Shmidov ◽

Olga Kryukov ◽

Dina Aranovich ◽

Smadar Cohen ◽

...

Keyword(s):

Functional Properties ◽

Peptide Conjugation ◽

Alginate Hydrogels ◽

Structure Properties

The mode and order of conjugating the heparin and the peptide to the alginate backbone greatly affect the modified alginate hydrogels’ structure–properties–function relations.

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Structural Features, Modification, and Functionalities of Beta-Glucan

Fibers ◽

10.3390/fib8010001 ◽

2019 ◽

Vol 8 (1) ◽

pp. 1 ◽

Cited By ~ 7

Author(s):

Ramandeep Kaur ◽

Minaxi Sharma ◽

Dawei Ji ◽

Min Xu ◽

Dominic Agyei

Keyword(s):

Molecular Weight ◽

Functional Properties ◽

Food Industry ◽

Food Product ◽

Structural Features ◽

Enzyme Hydrolysis ◽

Beta Glucan ◽

Chemical Agents ◽

Method Of Extraction ◽

Structure Properties

Β-glucan is a strongly hydrophilic non-starchy polysaccharide, which, when incorporated in food, is renowned for its ability to alter functional characteristics such as viscosity, rheology, texture, and sensory properties of the food product. The functional properties of β-glucans are directly linked to their origin/source, molecular weight, and structural features. The molecular weight and structural/conformational features are in turn influenced by method of extraction and modification of the β-glucan. For example, whereas physical modification techniques influence only the spatial structures, modification by chemical agents, enzyme hydrolysis, mechanical treatment, and irradiation affect both spatial conformation and primary structures of β-glucan. Consequently, β-glucan can be modified (via one or more of the aforementioned techniques) into forms that have desired morphological, rheological, and (bio)functional properties. This review describes how various modification techniques affect the structure, properties, and applications of β-glucans in the food industry.

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Crystallographic insight-guided nanoarchitectonics and conductivity modulation of an n-type organic semiconductor through peptide conjugation

Chemical Communications ◽

10.1039/c5cc01996f ◽

2015 ◽

Vol 51 (39) ◽

pp. 8315-8318 ◽

Cited By ~ 28

Author(s):

M. Pandeeswar ◽

Harshavardhan Khare ◽

Suryanarayanarao Ramakumar ◽

T. Govindaraju

Keyword(s):

Functional Properties ◽

Organic Semiconductor ◽

Structure Property ◽

Property Correlation ◽

Peptide Conjugation

Crystallographic insight-guided and bio-inspired molecular nanoarchitectonics of an n-type organic semiconductor is described to understand the structure–property correlation, for modulation of functional properties.

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Synthesis-atomic structure-properties relationships in metallic nanoparticles by total scattering experiments and 3D computer simulations: case of Pt–Ru nanoalloy catalysts

Nanoscale ◽

10.1039/c5nr00800j ◽

2015 ◽

Vol 7 (17) ◽

pp. 8122-8134 ◽

Cited By ~ 14

Author(s):

Binay Prasai ◽

Yang Ren ◽

Shiyao Shan ◽

Yinguang Zhao ◽

Hannah Cronk ◽

...

Keyword(s):

Functional Properties ◽

Computer Simulations ◽

3D Modeling ◽

Atomic Structure ◽

Metallic Nanoparticles ◽

Total Scattering ◽

Structure Properties

Total scattering coupled to 3D modeling resolves 3D atomic structure of metallic NPs providing clues to optimizing their functional properties.

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Quaternary structure of Limulus polyphemus hemocyanin

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100081747 ◽

1978 ◽

Vol 36 (2) ◽

pp. 176-177

Author(s):

T. Wichertjes ◽

E.J. Kwak ◽

E.F.J. Van Bruggen

Keyword(s):

Electron Microscopy ◽

Functional Properties ◽

Horseshoe Crab ◽

Temperature Jump ◽

Quaternary Structure ◽

Crystallographic Analysis ◽

Limulus Polyphemus ◽

Oxygen Binding ◽

X Ray ◽

Intact Molecule

Hemocyanin of the horseshoe crab (Limulus polyphemus) has been studied in nany ways. Recently the structure, dissociation and reassembly was studied using electron microscopy of negatively stained specimens as the method of investigation. Crystallization of the protein proved to be possible and X-ray crystallographic analysis was started. Also fluorescence properties of the hemocyanin after dialysis against Tris-glycine buffer + 0.01 M EDTA pH 8.9 (so called “stripped” hemocyanin) and its fractions II and V were studied, as well as functional properties of the fractions by NMR. Finally the temperature-jump method was used for assaying the oxygen binding of the dissociating molecule and of preparations of isolated subunits. Nevertheless very little is known about the structure of the intact molecule. Schutter et al. suggested that the molecule possibly consists of two halves, combined in a staggered way, the halves themselves consisting of four subunits arranged in a square.

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Trace nanoanalysis

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100172437 ◽

1994 ◽

Vol 52 ◽

pp. 940-941

Author(s):

D. E. Newbury ◽

R. D. Leapman

Keyword(s):

High Performance ◽

Secondary Ion Mass Spectrometry ◽

Detection Efficiency ◽

Volume Element ◽

And Performance ◽

Trace Constituents ◽

Secondary Ion ◽

Concentration Levels ◽

Structure Properties

Trace constituents, which can be very loosely defined as those present at concentration levels below 1 percent, often exert influence on structure, properties, and performance far greater than what might be estimated from their proportion alone. Defining the role of trace constituents in the microstructure, or indeed even determining their location, makes great demands on the available array of microanalytical tools. These demands become increasingly more challenging as the dimensions of the volume element to be probed become smaller. For example, a cubic volume element of silicon with an edge dimension of 1 micrometer contains approximately 5×1010 atoms. High performance secondary ion mass spectrometry (SIMS) can be used to measure trace constituents to levels of hundreds of parts per billion from such a volume element (e. g., detection of at least 100 atoms to give 10% reproducibility with an overall detection efficiency of 1%, considering ionization, transmission, and counting).

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Advancing the use of Voronoi–Dirichlet polyhedra to describe interactions in organic molecular crystal structures by the example of galunisertib polymorphs

CrystEngComm ◽

10.1039/d0ce01535k ◽

2021 ◽

Author(s):

Viktor N. Serezhkin ◽

Anton V. Savchenkov

Keyword(s):

Crystal Structures ◽

Molecular Crystal ◽

Noncovalent Interactions ◽

Organic Molecular Crystal ◽

Universal Approach ◽

Structure Properties

The universal approach for studying structure/properties relationships shows that every polymorph of galunisertib is characterized with unique noncovalent interactions.

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