scholarly journals Supramolecular assemblies of a 1,8-naphthalimide conjugate and its aggregation-induced emission property

2020 ◽  
Vol 1 (9) ◽  
pp. 3532-3538
Author(s):  
Souvik Misra ◽  
Pijush Singh ◽  
Ankita Das ◽  
Paula Brandão ◽  
Pathik Sahoo ◽  
...  
Keyword(s):  
Solid Solution ◽  
Cell Imaging ◽  
Supramolecular Assemblies ◽  
Emission Property ◽  
Aggregation Induced Emission ◽  
First Time

Here, we are reporting for the first time a simple naphthalimide derivative that undergoes assembly in the J-type manner in the solid, solution and gel state. It shows the aggregation-induced emission property and has been used for cell imaging.

Two spirobifluorene-based fluorescent probes with aggregation-induced emission properties: synthesis and application in the detection of Zn2+ and cell imaging

2019 ◽  
Vol 7 (8) ◽  
pp. 2240-2249 ◽  
Author(s):  
Jianyong Wan ◽  
Wu Zhang ◽  
Hongda Guo ◽  
JingJing Liang ◽  
Danyu Huang ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Cell Imaging ◽  
Aggregation Induced Emission ◽  
Emission Properties ◽  
First Time

The synthesis and application of two spirobifluorene-based probes with AIEE properties have been reported for the first time.

Unusual fluorescence of o-phenylazonaphthol derivatives with aggregation-induced emission and their use in two-photon cell imaging

2019 ◽  
Vol 55 (47) ◽  
pp. 6747-6750 ◽  
Author(s):  
Yeoju Yoon ◽  
Seonyoung Jo ◽  
Sang Jun Park ◽  
Hwan Myung Kim ◽  
Dongwook Kim ◽  
...  
Keyword(s):  
Cell Imaging ◽  
Aggregation Induced Emission ◽  
Two Photon ◽  
First Time

Unusual fluorescence of o-phenylazonaphthol derivatives with aggregated-induced emission (AIE) is reported for the first time, which can be used in two-photon cell imaging applications.

scholarly journals Intra-mitochondrial reaction for cancer cell imaging and anti-cancer therapy by aggregation-induced emission

RSC Advances ◽  
2020 ◽  
Vol 10 (71) ◽  
pp. 43383-43388
Author(s):  
Sangpil Kim ◽  
Juhee Kim ◽  
Batakrishna Jana ◽  
Ja-Hyoung Ryu
Keyword(s):  
Cancer Therapy ◽  
Cancer Cell ◽  
Chemical Reactions ◽  
Cell Imaging ◽  
Cellular Function ◽  
Aggregation Induced Emission ◽  
Cancer Cell Imaging ◽  
Anti Cancer

Controlled intracellular chemical reactions to regulate cellular function remain a challenge in biology mimetic systems.

scholarly journals Ultrasmall Organic Nanoparticles with Aggregation-Induced Emission and Enhanced Quantum Yield for Fluorescence Cell Imaging

2016 ◽  
Vol 88 (15) ◽  
pp. 7853-7857 ◽  
Author(s):  
Suying Xu ◽  
Xilin Bai ◽  
Jingwen Ma ◽  
Minmin Xu ◽  
Gaofei Hu ◽  
...  
Keyword(s):  
Quantum Yield ◽  
Cell Imaging ◽  
Organic Nanoparticles ◽  
Aggregation Induced Emission

scholarly journals Live-Cell Imaging of Caspase Activation for High-Content Screening

2009 ◽  
Vol 14 (8) ◽  
pp. 956-969 ◽  
Author(s):  
Christophe Antczak ◽  
Toshimitsu Takagi ◽  
Christina N. Ramirez ◽  
Constantin Radu ◽  
Hakim Djaballah
Keyword(s):  
Cell Death ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Exposure Period ◽  
Live Cells ◽  
Assay Method ◽  
Caspase Activation ◽  
Fluorogenic Substrate ◽  
Automated Imaging ◽  
First Time

Caspases are central to the execution of programmed cell death, and their activation constitutes the biochemical hallmark of apoptosis. In this article, the authors report the successful adaptation of a high-content assay method using the DEVDNucView488™ fluorogenic substrate, and for the first time, they show caspase activation in live cells induced by either drugs or siRNA. The fluorogenic substrate was found to be nontoxic over an exposure period of several days, during which the authors demonstrate automated imaging and quantification of caspase activation of the same cell population as a function of time. Overexpression of the antiapoptotic protein Bcl-XL, alone or in combination with the inhibitor Z-VAD-FMK, attenuated caspase activation in HeLa cells exposed to doxorubicin, etoposide, or cell death siRNA. This method was further validated against 2 well-characterized NSCLC cell lines reported to be sensitive (H3255) or refractory (H2030) to erlotinib, where the authors show a differential time-dependent activation was observed for H3255 and no significant changes in H2030, consistent with their respective chemosensitivity profile. In summary, the results demonstrate the feasibility of using this newly adapted and validated high-content assay to screen chemical or RNAi libraries for the identification of previously uncovered enhancers and suppressors of the apoptotic machinery in live cells. ( Journal of Biomolecular Screening 2009:956-969)

Pillar[5]arene-based supramolecular assemblies with two-step sequential fluorescence enhancement for mitochondria-targeted cell imaging

2020 ◽  
Vol 8 (44) ◽  
pp. 15622-15625
Author(s):  
Hao Guo ◽  
Xin Yan ◽  
Bing Lu ◽  
Jin Wang ◽  
Xiaolei Yuan ◽  
...  
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Fluorescence Enhancement ◽  
Fluorescence Emission ◽  
Supramolecular Assemblies ◽  
Live Cell ◽  
Supramolecular Nanoparticles

Two-step sequential fluorescence emission enhanced supramolecular nanoparticles are constructed from pillar[5]arene based host–guest interaction and a linear amphiphile. These supramolecular nanoparticles can be applied in mitochondria-targeted live cell imaging.

Supramolecular enhancement of aggregation-induced emission and its application in cancer cell imaging

2014 ◽  
Vol 2 (32) ◽  
pp. 6609-6617 ◽  
Author(s):  
Guocan Yu ◽  
Guping Tang ◽  
Feihe Huang
Keyword(s):  
Ternary System ◽  
Cancer Cells ◽  
Cancer Cell ◽  
Cell Imaging ◽  
Imaging Agent ◽  
Aggregation Induced Emission ◽  
Cancer Cell Imaging

A ternary system of two tetraphenylethene derivatives containing naphthalene and paraquat groups, respectively, and a pillar[6]arene is utilized as an imaging agent for cancer cells.

Host–guest interaction enhanced aggregation-induced emission and its application in cell imaging

2016 ◽  
Vol 52 (33) ◽  
pp. 5749-5752 ◽  
Author(s):  
Jiong Zhou ◽  
Bin Hua ◽  
Li Shao ◽  
Hao Feng ◽  
Guocan Yu
Keyword(s):  
Inclusion Complex ◽  
Cell Imaging ◽  
Aggregation Induced Emission

A host–guest inclusion complex based on a monofunctionalized pillar[5]arene and a tetraphenylethene derivative was prepared, resulting in an enhanced emission from the tetraphenylethene-based guest, which was applied in cell imaging.

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