scholarly journals Needle-free delivery of fluids from compact laser-based jet injector

Lab on a Chip ◽  
2020 ◽  
Vol 20 (20) ◽  
pp. 3784-3791
Author(s):  
Jan Krizek ◽  
Frédéric De Goumoëns ◽  
Paul Delrot ◽  
Christophe Moser
Keyword(s):  
Laser Pulse ◽  
Minimally Invasive ◽  
Optical Fibre ◽  
Jet Injection ◽  
Free Jet ◽  
Actuation Mechanism ◽  
Invasive Device ◽  
Minimally Invasive Device

We present a needle-free jet injection from the minimally invasive device. The actuation mechanism is based on optical cavitation by a laser pulse transported via optical fibre.

Minimally-invasive device-based approaches for improving cardiac perfusion

2020 ◽  
pp. 623-647
Author(s):  
Gramegna Mario ◽  
Ponticelli Francesco ◽  
Baldetti Luca ◽  
Gallone Guglielmo ◽  
Regazzoli Damiano ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Cardiac Perfusion ◽  
Invasive Device ◽  
Minimally Invasive Device

scholarly journals A Minimally Invasive Device for Continuous Glucose Monitoring in Infants

2008 ◽  
Vol 2 (2) ◽  
Author(s):  
Christopher P. Erdman ◽  
Stephen M. Goldman ◽  
Patrick J. Lynn ◽  
Matthew C. Ward
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Minimally Invasive ◽  
Neonatal Intensive Care Unit ◽  
Continuous Glucose Monitoring ◽  
Neonatal Intensive Care ◽  
Glucose Monitoring ◽  
Polarized Light ◽  
Invasive Device ◽  
Minimally Invasive Device

Blood sugar management is particularly critical in the neonatal intensive care unit where the incidence of hypoglycemia is high and patients run the risk of brain damage. The staff at most hospitals obtain glucose levels in infants by drawing blood from the heel, which is a cause for recurrent pain. Some infants undergo this procedure every 1–3hours for up to a few months. Our goal is to design a minimally invasive device that allows for real-time glucose monitoring in very low birth weight infants in the neonatal intensive care unit (NICU). This glucose monitor will reduce the amount of pain and physiological stress on the infants, decrease the risk of hypoglycemia in neonates and reduce the workload on hospital staff. There is currently much room for emerging technologies in this market as it trends towards less pain and faster responses. The device should only slightly hinder the infant’s motion, be as painless as possible, and all materials used in contact with the body need to be biologically inert and cause no irritation or allergic reaction. The device will utilize a microneedle array to extract interstitial fluid and draw it through a hydrophilic polyurethane membrane and into a polarimetry chamber. Circularly polarized light will be passed through the chamber and the differential absorbance of left and right polarized light will be used to calculate the glucose concentration. A literature and patent review showed that each separate portion could be used in an effective device for minimally invasive, continuous glucose monitoring.

scholarly journals RheoSens; RheoPatch

2020 ◽  
Author(s):  
Tariq H. Khan
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Intracranial Pressure ◽  
Minimally Invasive ◽  
Brain Injuries ◽  
Tissue Oxygenation ◽  
Traumatic Brain Injuries ◽  
Invasive Device ◽  
The Brain ◽  
Minimally Invasive Device

Rheo Probe is a minimally invasive device, implanted in the brain matter for patients in a coma following brain haemorrage or traumatic brain injuries to measure cerebral blood flow, intracranial pressure, temperature and oxygenation parameters. Nearinfrared sensors assess levels of tissue oxygenation as well as cerebral blood flow by measuring oxygenated and deoxygenated hemoglobin based on spectrometry.

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