Multiplexed homogeneous digital immunoassay based on single-particle motion analysis

Lab on a Chip ◽  
2020 ◽  
Vol 20 (12) ◽  
pp. 2113-2121 ◽  
Author(s):  
Kenji Akama ◽  
Hiroyuki Noji

Homogeneous digital immunoassay is a powerful analytical method for highly sensitive biomarker detection with a simple protocol. By using this method, we demonstrated the simultaneous multiple protein detection.

The Analyst ◽  
2021 ◽  
Author(s):  
Kenji Akama ◽  
Hiroyuki Noji

Digital homogeneous non-enzymatic immunosorbent assay (digital Ho-Non ELISA) is a new class of digital immunoassay. In this paper, we developed a multiparameter single-particle motion analysis method for a highly sensitive digital Ho-Non ELISA.


ACS Nano ◽  
2019 ◽  
Vol 13 (11) ◽  
pp. 13116-13126 ◽  
Author(s):  
Kenji Akama ◽  
Niina Iwanaga ◽  
Koya Yamawaki ◽  
Masaki Okuda ◽  
Krupali Jain ◽  
...  

1987 ◽  
Vol 37 (3) ◽  
pp. 497-506
Author(s):  
M. C. Festeau-Barrioz ◽  
M. L. Sawley ◽  
J. Václavík

The motion of a single particle under the influence of the ponderomotive force directed perpendicular to the external magnetostatic field is analysed. By solving the exact equation of motion for a specific applied electromagnetic field, the resultant ponderomotive drift is compared with the prediction of a single-particle theory using the oscillation-centre approximation. The regime of validity of this theory is discussed. It is shown that, for certain values of the amplitude and frequency of the electromagnetic field, the particle motion is unstable and therefore the concept of a single-particle ponderomotive force is meaningless.


1979 ◽  
Vol 19 (1) ◽  
pp. 416-418 ◽  
Author(s):  
H. van Beijeren ◽  
J. R. Dorfman

1983 ◽  
Vol 314 (3) ◽  
pp. 309-316 ◽  
Author(s):  
W. Cassing ◽  
A. K. Dhar ◽  
A. Lukasiak ◽  
W. N�renberg

2020 ◽  
pp. 29-60
Author(s):  
Christopher W. Kulp ◽  
Vasilis Pagonis

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