Computer-aided nanotoxicology: risk assessment of metal oxide nanoparticles via nano-QSAR

2020 ◽  
Vol 22 (11) ◽  
pp. 3512-3521 ◽  
Author(s):  
Jiakai Cao ◽  
Yong Pan ◽  
Yanting Jiang ◽  
Ronghua Qi ◽  
Beilei Yuan ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Metal Oxide ◽  
Predictive Models ◽  
Computational Study ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Computer Aided ◽  
Acute Cytotoxicity

A combined experimental and computational study is performed to estimate the acute cytotoxicity and develop predictive models for MeOx NPs.

Second generation periodic table-based descriptors to encode toxicity of metal oxide nanoparticles to multiple species: QSTR modeling for exploration of toxicity mechanisms

2018 ◽  
Vol 5 (11) ◽  
pp. 2742-2760 ◽  
Author(s):  
Priyanka De ◽  
Supratik Kar ◽  
Kunal Roy ◽  
Jerzy Leszczynski
Keyword(s):  
Risk Assessment ◽  
Metal Oxide ◽  
In Silico ◽  
Periodic Table ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Gap Filling ◽  
Toxicity Mechanisms ◽  
Data Gap ◽  
Multiple Species

The application of in silico methods in the risk assessment of metal oxide nanoparticles (MNPs) and data gap filling has found profound usability.

scholarly journals Toward computational and experimental characterisation for risk assessment of metal oxide nanoparticles

2018 ◽  
Vol 5 (10) ◽  
pp. 2241-2251
Author(s):  
Laura Escorihuela ◽  
Benjamí Martorell ◽  
Robert Rallo ◽  
Alberto Fernández
Keyword(s):  
Risk Assessment ◽  
Metal Oxide ◽  
In Silico ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Toxicity Evaluation ◽  
Experimental Characterisation

In silicomethods provide an alternative and reliable route for the toxicity evaluation of metal oxide nanoparticles.

Star fruit extract-mediated green synthesis of metal oxide nanoparticles

2021 ◽  
pp. 1-8
Author(s):  
Sagadevan Suresh ◽  
Selvaraj Vennila ◽  
J. Anita Lett ◽  
Is Fatimah ◽  
Faruq Mohammad ◽  
...  
Keyword(s):  
Metal Oxide ◽  
Green Synthesis ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Fruit Extract ◽  
Star Fruit

Quantum mechanics descriptors in a nano-QSAR model to predict metal oxide nanoparticles toxicity in human keratinous cells

2021 ◽  
Vol 23 (8) ◽  
Author(s):  
Eliecer Peláez Sifonte ◽  
Fidel Antonio Castro-Smirnov ◽  
Argenis Adrian Soutelo Jimenez ◽  
Héctor Raúl González Diez ◽  
Fernando Guzmán Martínez
Keyword(s):  
Quantum Mechanics ◽  
Metal Oxide ◽  
Metal Oxide Nanoparticles ◽  
Qsar Model ◽  
Oxide Nanoparticles ◽  
Nanoparticles Toxicity

scholarly journals Controlling the optical properties of nanostructured oxide-based polymer films

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
N. C. Angastiniotis ◽  
S. Christopoulos ◽  
K. C. Petallidou ◽  
A. M. Efstathiou ◽  
A. Othonos ◽  
...  
Keyword(s):  
Optical Properties ◽  
Metal Oxide ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Optimal Size ◽  
Specific Chemical ◽  
Nanostructured Oxide ◽  
Bulk Scale ◽  
Transmission And Reflection ◽  
Film Composites

AbstractA bulk scale process is implemented for the production of nanostructured film composites comprising unary or multi-component metal oxide nanoparticles dispersed in a suitable polymer matrix. The as-received nanoparticles, namely Al$$_2$$ 2 O$$_3$$ 3 , SiO$$_2$$ 2 and TiO$$_2$$ 2 and binary combinations, are treated following specific chemical and mechanical processes in order to be suspended at the optimal size and composition. Subsequently, a polymer extrusion technique is employed for the fabrication of each film, while the molten polymer is mixed with the treated metal oxide nanoparticles. Transmission and reflection measurements are performed in order to map the optical properties of the fabricated, nanostructured films in the UV, VIS and IR. The results substantiate the capability of the overall methodology to regulate the optical properties of the films depending on the type of nanoparticle formation which can be adjusted both in size and composition.

scholarly journals The application prospect of metal/metal oxide nanoparticles in the treatment of osteoarthritis

2021 ◽  
Vol 394 (10) ◽  
pp. 1991-2002
Author(s):  
Junchao Luo ◽  
Yin Zhang ◽  
Senbo Zhu ◽  
Yu Tong ◽  
Lichen Ji ◽  
...  
Keyword(s):  
Metal Oxide ◽  
Metal Oxide Nanoparticles ◽  
Biological Response ◽  
Cell Uptake ◽  
Oxide Nanoparticles ◽  
Therapeutic Effects ◽  
Superoxide Anions ◽  
Metal Metal ◽  
Cartilage Wear

AbstractThe current understanding of osteoarthritis is developing from a mechanical disease caused by cartilage wear to a complex biological response involving inflammation, oxidative stress and other aspects. Nanoparticles are widely used in drug delivery due to its good stability in vivo and cell uptake efficiency. In addition to the above advantages, metal/metal oxide NPs, such as cerium oxide and manganese dioxide, can also simulate the activity of antioxidant enzymes and catalyze the degradation of superoxide anions and hydrogen peroxide. Degrading of metal/metal oxide nanoparticles releases metal ions, which may slow down the progression of osteoarthritis by inhibiting inflammation, promoting cartilage repair and inhibiting cartilage ossification. In present review, we focused on recent research works concerning osteoarthritis treating with metal/metal oxide nanoparticles, and introduced some potential nanoparticles that may have therapeutic effects.

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