Comprehensive phytochemical analysis and sedative-hypnotic activity of two Acanthopanax species leaves

2021 ◽  
Author(s):  
Yunhe Liu ◽  
Zhongyao Wang ◽  
Caixia Wang ◽  
Hanrui Si ◽  
Hui Yu ◽  
...  
Keyword(s):  
Phytochemical Analysis ◽  
Pharmacological Activities ◽  
Acanthopanax Senticosus ◽  
Acanthopanax Sessiliflorus ◽  
Hypnotic Activity ◽  
Acanthopanax Species

Acanthopanax senticosus leaves (SCL) and Acanthopanax sessiliflorus leaves (SFL), which are usually made into functional teas, possess similar pharmacological activities.

scholarly journals A Comparative Metabolomics Analysis Reveals the Tissue-Specific Phenolic Profiling in Two Acanthopanax Species

Molecules ◽  
2018 ◽  
Vol 23 (8) ◽  
pp. 2078 ◽  
Author(s):  
Ke-Xin Wu ◽  
Jia Liu ◽  
Yang Liu ◽  
Xiao-Rui Guo ◽  
Li-Qiang Mu ◽  
...  
Keyword(s):  
High Performance ◽  
Acanthopanax Senticosus ◽  
Liquid Chromatograph ◽  
Active Compounds ◽  
Tissue Specific ◽  
Eleutheroside B ◽  
Specific Accumulation ◽  
Comparative Metabolomics ◽  
Acanthopanax Sessiliflorus ◽  
Acanthopanax Species

Acanthopanax senticosus (Rupr. Maxim.) Harms (ASH) and Acanthopanax sessiliflorus (Rupr. Maxim.) Seem (ASS), are members of the Araliaceae family, and both are used in Asian countries. These herbals have drawn much attention in recent years due to their strong biological activity, with innocuity and little side effects. However, the common and distinct mode of compound profiles between ASH and ASS is still unclear. In this study, a high performance liquid chromatograph-mass spectrometry (HPLC-MS) method was developed to simultaneously quantify the seven major active compounds, including protocatechuate, eleutheroside B, eleutheroside E, isofraxidin, hyperoside, kaempferol and oleanolic acid. Then the targeted metabolomics were conducted to identify 19 phenolic compounds, with tight relation to the above mentioned active compounds, including nine C6C3C6-type, six C6C3-type and four C6C1-type in the two Acanthopanax species studied here. The results showed that the seven active compounds presented a similar trend of changes in different tissues, with more abundant accumulation in roots and stems for both plants. From the view of plant species, the ASH plants possess higher abundance of compounds, especially in the tissues of roots and stems. For phenolics, the 19 phenols detected here could be clearly grouped into five main clusters based on their tissue-specific accumulation patterns. Roots are the tissue for the most abundance of their accumulations. C6C3C6-type compounds are the most widely existing type in both plants. In conclusion, the tissue- and species-specificity in accumulation of seven active compounds and phenolics were revealed in two Acanthopanax species.

Bryophyllum Pinnatum: A Review on Medicinal Benefits and Potent Bioactive Molecules

2020 ◽  
Vol 16 (7) ◽  
pp. 978-992
Author(s):  
Punit Kumar ◽  
Sujata Malik ◽  
Kashyap K. Dubey
Keyword(s):  
Web Of Science ◽  
Folk Medicine ◽  
Bioactive Molecules ◽  
Phytochemical Analysis ◽  
Traditional Herbal Medicine ◽  
Pharmacological Activities ◽  
Online Databases ◽  
Natural Remedies ◽  
Medicinal Properties ◽  
Bryophyllum Pinnatum

Background: Since its inception, people are using herbal extracts as natural remedies for the treatment of various diseases. Bryophyllum pinnatum, also known as the air plant, is a well-recognized herb used in folk medicine. It is native to Madagascar and further planted in tropical and subtropical areas around the world. It is known for the profusion of miniature plantlets which arise from the margins of phylloclade. Objective: The aim of this review is to provide the information regarding local and traditional uses, pharmacological activities and different phytochemicals reported from leaves extracts of Bryophyllum pinnatum. Methods: This review article contains a detailed survey of the literature about Bryophyllum pinnatum available in different online databases, such as; PubMed, Web of Science, Science Direct, Elsevier, and Google Scholar, etc. In this review, authors have focused on ethnopharmacological importance and phytochemicals present in Bryophyllum pinnatum and their structure. The structures of the phytochemical were prepared by the ChemDraw tool. Results: This plant is used as a traditional herbal medicine around the globe due to medicinal properties like; anthelmintic, immunosuppressive, hepatoprotective, antinociceptive, anti-inflammatory, antidiabetic, nephroprotective, antioxidant, antimicrobial, analgesic, anticonvulsant and antipyretic. Phytochemical analysis revealed the presence of many bioactive compounds like; alkaloids, flavonoids, triterpenes, steroids, glycosides, bufadienolides, lipids, and organic acids, etc. which are associated with different medicinal properties. Conclusion: Bryophyllum pinnatum possesses diverse pharmacological importance and remarkable medicinal properties. Investigators have reported a large number of phytochemicals exhibiting different medicinal properties and correlation of medicinal properties.

scholarly journals Ethno-medicinal, phytochemistry, and pharmacological importance of Hunteria umbellate (K. Schum.) Hallier f. (Apocynaceae): a useful medicinal plant of sub-Saharan Africa

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Olumide Samuel Fadahunsi ◽  
Peter Ifeoluwa Adegbola ◽  
Olubukola Sinbad Olorunnisola ◽  
Temitayo Idris Subair ◽  
David Oluwasegun Adepoju ◽  
...  
Keyword(s):  
Tropical Rainforest ◽  
Biological Activities ◽  
Folk Medicine ◽  
Sub Saharan Africa ◽  
Phytochemical Analysis ◽  
Menstrual Pain ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Intestinal Worms ◽  
Sub Saharan

Abstract Background Hunteria umbellate (K. Schum.) Hallier f. (Apocynaceae) is a tropical rainforest tree commonly found in sub-Saharan region of Africa. It is a useful and very popular plant among the locals due to the outstanding anti-diabetic activity of the seeds. Methods A comprehensive literature search on articles published on phytochemical analysis and various pharmacological activities of Hunteria umbellate was carried out using search engines such as Google Scholar, PubMed and Science Direct. Results In this review, it was deduced that H. umbellate is employed in folk medicine as an elixir for obesity, fever, leprosy sores, menstrual pain, infertility, yaws, intestinal worms, abdominal discomfort and stomach ache. Due to their durability and immunity against termites, the stems are coveted and desired as timbers in the construction of houses, while the bark has been reportedly exported to Europe for medicinal uses. Pharmacological activities such as fertility enhancing, aphrodisiac, hypoglycemic, anti-inflammatory, has been ascribed to the different morphological organs of H. umbellate. Moreover, compounds belonging to important classes of secondary metabolites with biological activities such as triterpenoids, flavonoids, tannins, alkaloids, quinic acids have been identified and characterized from the plant. Conclusion From this review, it can be inferred that, numerous and bioactive principles with known biological usefulness are present in the extracts of H. umbellate and might be responsible for the observed biological and pharmacological activities.

scholarly journals The bioactive ingredients and therapeutic effects of Marrubium vulgare - A review

2021 ◽  
Vol 1 (2) ◽  
pp. 09-021
Author(s):  
Ali Esmail Al-Snafi ◽  
Hussein Ali Al-Saedy ◽  
Tayseer Ali Talab ◽  
Wajdi Jabbar Majid ◽  
Gaber El-Saber Batiha ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Night Blindness ◽  
Biological Effects ◽  
Phytochemical Analysis ◽  
Therapeutic Effects ◽  
Pulmonary Infections ◽  
Pharmacological Activities ◽  
Marrubium Vulgare ◽  
Bioactive Ingredients ◽  
Loss Of Appetite

Marrubium vulgare (Family: Lamiaceae) was used traditionally in the treatment of dyspeptic complains, pulmonary infections, cough, rheumatoid arthritis, night blindness, loss of appetite, as cholagogue, purgative, diuretic, bitter tonic, carminative and appetizer. The phytochemical analysis revealed that the plant contained alkaloids, sterols, steroids, terpenoids (diterpene), saponins, flavonoid, catecholic tannins, anthocyans, phenolic compounds and many other bioactive ingredients. The pharmacological investigations showed that the plant exerted anti-inflammatory, antiedematogenic, analgesic, antioxidant, antimicrobial, antidiabetic, cardiovascular hypolipidemic, antispasmodic and many other biological effects. This review discussed the bioactive contents and pharmacological activities of Marrubium vulgare.

scholarly journals A STUDY ON THE STANDARDIZATION PARAMETERS OF BAUHINIA VARIEGATA

2017 ◽  
Vol 10 (4) ◽  
pp. 133 ◽  
Author(s):  
Pragati Khare ◽  
Kamal Kishore ◽  
Dinesh Kumar Sharma
Keyword(s):  
Herbal Medicines ◽  
Phytochemical Analysis ◽  
Pharmacological Properties ◽  
Lower Epidermis ◽  
Pharmacological Activities ◽  
Fluorescence Studies ◽  
The Family ◽  
Microscopic Studies ◽  
Leaf Powder ◽  
Bauhinia Variegata

Objective: In today’s scenario, the herbal medicines are much efficient for the treatment of various disorders as they have minimal side effects incomparison to the allopathic medicines. Bauhinia variegata L. (Mountain Ebony), commonly called Kachnar, belongs to the family Leguminosae.It is a medium-sized tree, mostly found at an altitude of 1300 m in the Himalayas. The objectives of the present study are to investigate variouspharmacognostic, phytochemical analysis, and pharmacological properties of B. variegata.Methods: The powdered drug was used for estimating the loss on drying, ash values, fluorescence studies, chemical tests, and extractive values.Macroscopic and microscopic studies were also performed.Results: The leaf microscopy revealed the presence of upper and lower epidermis, palisade tissue, well-developed vascular bundle. The fluorescencecharacteristics of leaf powder were studied both in visible light and ultraviolet light (254 nm and 365 nm) after treatment with various reagents.Kachnar is composed of carbohydrates, tannins, alkaloids, flavonoids, amino acid. It was reported that the total ash value was 8.15%. The acidinsoluble ash value was 5.5%.Conclusion: The main pharmacological activities of B. variegata are anthelmintic, antiulcer, antitumor, antimicrobial, antidiabetic, anti-inflammatory, antigoitrogenic, and hepatoprotective. The present investigation provides the information on its pharmacognostic, phytochemical analysis, andpharmacological properties.Keywords: Flavonoids, Kachnar, Alkaloids, Antioxidant, Leguminosae.

scholarly journals URARIA PICTA (JACQ.): A REVIEW ON ETHNOMEDICAL USES, PHYTOCHEMISTRY, AND BIOLOGICAL ACTIVITIES

2021 ◽  
pp. 40-44
Author(s):  
JAYKUMAR MANE ◽  
DHEERAJ NAGORE ◽  
SOHAN CHITLANGE
Keyword(s):  
Biological Activities ◽  
Future Research ◽  
Phytochemical Analysis ◽  
Pharmacological Activities ◽  
Technological Potential ◽  
Depth Study ◽  
Toxicological Research ◽  
Commercial Research

The aim of this systematic review is to provide an in-depth study of ethnological uses, phyto-chemistry, pharmacological activities, and toxicological research in Uraria picta (Jacq.), to identify remaining gaps, and to provide a basis for future research. By searching for the words “U. picta” and “Prishnaparni” in electronic databases such as SciFinder, Web of Science, PubMed, and Google Scholar, information on common uses, phytochemistry, and pharmacological activities was systematically collected. Phytochemical analysis of U. picta shows various components such as alkaloids, flavonoids, steroids, terpenoids, phenols, and saponins. The extracts and their isolated components showed numerous in vitro and in vivo pharmacological effects, including urinary tract diseases, tumors, edema, smoking, and dyspnea. On the other hand, searches of patent databases found almost seven applications, highlighting the differences between a large number of published scientific articles and non-existent patent applications. This event demonstrates the technological potential of undiscovered species. Ethnographic research shows that U. picta, an important Asian medicinal plant, is used to treat many diseases. In this review, the ethnobotanical, phytochemical, pharmacological, and ethnological properties of various morphological parts of the U. picta plant are highlighted. Future research has provided information for commercial research and has shown that this herb has tremendous potential for pharmaceutical and nutritional applications.

scholarly journals Phytochemical screening and biological assays of ethanolic leaf extract of Senna rugosa

Rodriguésia ◽  
2020 ◽  
Vol 71 ◽  
Author(s):  
Letícia Figueiredo Cunha ◽  
Camila Marques Costa ◽  
Poliana Ribeiro Barroso ◽  
Kelly Cristina Kato ◽  
Fabrício de Oliveira ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Leaf Extract ◽  
Antimicrobial Activities ◽  
Antitumoral Activity ◽  
Phytochemical Analysis ◽  
Pharmacological Activities ◽  
Biological Assays ◽  
Popular Medicine ◽  
Candida Famata ◽  
Ethanolic Leaf Extract

Abstract Senna rugosa (Fabaceae) is a common specie of the Brazilian territory, especially in the Cerrado biome. It is widely used in the popular medicine although not yet adequately investigated as to its phytoconstituents and pharmacological activities. In this study, the preliminary phytochemical analysis of ethanolic leaf extract of S. rugosa was performed and its cytotoxicity, antitumoral and antimicrobial activities (antibacterial, antifungal, anti-Trypanosoma and anti-Leishmania) were evaluated. The crude extract was analyzed in HPLC-DAD and fractions were also characterized using GC-MS and ESI-MS techniques. Results indicate phenolic compounds majority presence, including flavonol, anthraquinone and anthrones derivatives. Relative antimicrobial activities were detected against Staphylococcus aureus, Pseudomonas aeruginosa, Candida famata, Candida krusei and Candida tropicalis. As well as, a weak anti-trypanosomatids activity against M2269 strain and BH46 strain of Leishmania sp. A relative antitumoral activity was also identified but in counterpoint were also observed a toxicity in fibroblast cells (L929). Phytochemically, results provide evidence that phenolic compounds in S. rugosa leaves might be the responsible for its antimicrobial activity and cell toxicity inferred in our research.

scholarly journals Secondary metabolites in plants: main classes, phytochemical analysis and pharmacological activities

Bionatura ◽  
2019 ◽  
Vol 4 (4) ◽  
pp. 1000-1009
Author(s):  
Irina Francesca González Mera ◽  
Daniela Estefanía González Falconí ◽  
Vivian Morera Córdova
Keyword(s):  
Secondary Metabolites ◽  
Secondary Metabolism ◽  
Chemical Compounds ◽  
Biological Properties ◽  
Phytochemical Analysis ◽  
Phytochemical Screening ◽  
Biological Functions ◽  
Pharmacological Activities

Plants are an essential source of chemical compounds with different biological properties that man can use to his advantage. These substances are mainly produced as a result of chemical conversions of secondary metabolism. This article reviews the main classes of secondary metabolites that synthesize plants as well as their characteristics and their biological functions. Examples are provided for each of the classes. Emphasis is placed on the methods of extracting secondary metabolites and phytochemical screening, as well as on the main pharmacological activities described for the MS.

A comprehensive review on the ethnobotany, phytochemistry, pharmacology, and toxicology of Mentha aquatic L (water mint) as a wild shallow vegetable

2021 ◽  
Vol 27 ◽  
Author(s):  
Farzaneh Asadollah-Pour ◽  
Asieh Jokar ◽  
Ebrahim Nasiri ◽  
Mohammad Azadbakht ◽  
Zohreh Bari ◽  
...  
Keyword(s):  
Intestinal Parasites ◽  
Phytochemical Analysis ◽  
Pharmacological Activities ◽  
Future Studies ◽  
Mentha Aquatica ◽  
Food Industries ◽  
Perennial Plant ◽  
Anti Oxidant ◽  
Intestinal Worms ◽  
Pharmacology And Toxicology

: Mentha spp. are aromatic plants and have been used in the medical, cosmetics, and food industries. These plants have been used as a traditional herbal medicine for various types of diseases. Mentha aquatica L. (water mint) is a perennial plant used as a wild vegetable and a culinary herb. As its name suggests, it grows in the shallow margins and channels of streams, rivers, wet meadows, etc. It has been used as a tonic plant, sedative, and soothing for intestinal parasites, constipation, diarrhea, stomach troubles, biliousness, liver diseases, impotence, low or high blood pressure, expelling intestinal worms in children, enhancing longevity. Researchers from all over the world have studied the chemical composition and pharmacological activities of this plant, such as its anti-microbial, anti-inflammatory, anti-oxidant activities. In addition, the neurochemical properties, larvicidal activity and phytochemical analysis of the plant have also been reported. However, there is no review article available that gathers all the information and provides insights for future studies on M. aquatica. Against this backdrop, the present research is conducted to categorize the published studies and to offer more suggestions to researchers for future studies.

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