scholarly journals Phenolic compounds: current industrial applications, limitations and future challenges

2021 ◽  
Author(s):  
Bianca R. Albuquerque ◽  
Sandrina A. Heleno ◽  
M. Beatriz P. P. Oliveira ◽  
Lillian Barros ◽  
Isabel C. F. R. Ferreira
Keyword(s):  
Phenolic Compounds ◽  
Secondary Metabolites ◽  
Industrial Application ◽  
Chemical Structure ◽  
Industrial Applications ◽  
Future Challenges

Phenolic compounds (PC) are secondary metabolites with interesting bioactivities that have been explored for industrial application. PC bioactivity depends on their chemical structure integrity, so, methods to increase PC stability have been developed.

scholarly journals Metabolites from Macroalgae and Its Applications in the Cosmetic Industry: A Circular Economy Approach

Resources ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 101 ◽  
Author(s):  
Catarina Lourenço-Lopes ◽  
Maria Fraga-Corral ◽  
Cecilia Jimenez-Lopez ◽  
Antia G. Pereira ◽  
Paula Garcia-Oliveira ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Phenolic Compounds ◽  
Secondary Metabolites ◽  
Circular Economy ◽  
Industrial Applications ◽  
Marine Macroalgae ◽  
Gelling Agents ◽  
Industrial Sectors ◽  
Cosmetic Industry ◽  
The World

Marine macroalgae are a suitable source of ingredients due to their huge diversity, availability and nutritional and chemical composition. Their high content in proteins, carbohydrates and vitamins, but also in secondary metabolites such as phenolic compounds, terpenoids or pigments, make them great candidates for industrial applications. The cosmetic industry is one of the biggest in the world and the search for new ingredients is constantly growing as the consumer trend now is going back to those traditional cosmetics with a more natural composition. Moreover, the concept of a circular economy is also gaining importance due to the unsustainable situation of the natural resources. Although macroalgae are already used in cosmetics, especially as thickening and gelling agents, they possess an unexplored potential, not only as excipients and additives but also as a source of new active ingredients. In this context, macroalgae are considered in many cases as resources still underexploited and they could even be obtained from the waste of other industrial sectors and be used for recovering active molecules. Therefore, the aim of this review is to compile information about the different macroalgae metabolites and their possible applications in the cosmetic industry, which could employ circular economy models.

scholarly journals Highlights on Chaetomium morphology, secondary metabolites and biological activates

2020 ◽  
Vol 4 (1) ◽  
pp. 01-05
Author(s):  
Waill Elkhateeb
Keyword(s):  
Secondary Metabolites ◽  
Endophytic Fungi ◽  
Industrial Application ◽  
Therapeutic Agents ◽  
Industrial Applications

Endophytic fungi always attract attention due to their generous production of bioactive and chemically novel compounds that have medical, agriculture, industrial applications. This review focused on Chaetomium as a model of endophytic fungi rich in therapeutic agents that have known medicinal and industrial application. Moreover, understanding the importance of this potent fungus encourage further studies to identify novel metabolites, and at the same time employing already known metabolites to evaluate their activity in order to be used in additional applications.

scholarly journals Ultrasonic-Assisted Extraction and Natural Deep Eutectic Solvents Combination: A Green Strategy to Improve the Recovery of Phenolic Compounds from Lavandula pedunculata subsp. lusitanica (Chaytor) Franco

Antioxidants ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 582
Author(s):  
Inês Mansinhos ◽  
Sandra Gonçalves ◽  
Raquel Rodríguez-Solana ◽  
José Luis Ordóñez-Díaz ◽  
José Manuel Moreno-Rojas ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Deep Eutectic Solvents ◽  
Industrial Applications ◽  
Total Phenolic ◽  
Ultrasound Assisted Extraction ◽  
Phenolic Contents ◽  
Assisted Extraction ◽  
Natural Deep Eutectic Solvents ◽  
Ultrasonic Assisted

The present study aimed at evaluating the effectiveness of different natural deep eutectic solvents (NADES) on the extraction of phenolic compounds from Lavandula pedunculata subsp. lusitanica (Chaytor) Franco, on the antioxidant activity, and acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and tyrosinase (Tyr) inhibitory capacities. Ten different NADES were used in this research and compared with conventional solvents. Ultrasound-assisted extraction (UAE) for 60 min proved to be the best extraction condition, and proline:lactic acid (1:1) and choline chloride:urea (1:2) extracts showed the highest total phenolic contents (56.00 ± 0.77 mgGAE/gdw) and antioxidant activity [64.35 ± 1.74 mgTE/gdw and 72.13 ± 0.97 mgTE/gdw in 2.2-diphenyl-1-picrylhydrazyl (DPPH) and 2.2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) methods, respectively]. These extracts also exhibited enzymes inhibitory capacity particularly against Tyr and AChE. Even so, organic acid-based NADES showed to be the best extractants producing extracts with considerable ability to inhibit enzymes. Twenty-four phenolic compounds were identified by HPLC-HRMS, being rosmarinic acid, ferulic acid and salvianolic acid B the major compounds. The results confirmed that the combination of UAE and NADES provide an excellent alternative to organic solvents for sustainable and green extraction, and have huge potential for use in industrial applications involving the extraction of bioactive compounds from plants.

Physiological Effect of Lichen Secondary Metabolites on the Lichen Parasite Marchandiomyces Corallinus

1999 ◽  
Vol 31 (3) ◽  
pp. 307-314 ◽  
Author(s):  
A. P. Torzilli ◽  
P. A. Mikelson ◽  
J. D. Lawrey
Keyword(s):  
Catalytic Activity ◽  
Phenolic Compounds ◽  
Secondary Metabolites ◽  
Host Preference ◽  
Secondary Compounds ◽  
Physiological Effect ◽  
Physiological Adaptation ◽  
Secondary Chemistry ◽  
Physiological Basis ◽  
Lichenicolous Fungi

AbstractIt has been suggested that the host specificity exhibited by some lichenicolous fungi depends on their ability to tolerate the secondary chemistry of potential host lichens. For example, the lichen parasite Marchandiomyces corallinus is able to degrade the tissues of the lichen Flavoparmelia baltimorensis irrespective of the presence or absence of endogenous phenolic compounds. In contrast, the degradation of tissues from the lichen Lasallia papulosa is suppressed when endogenous phenolics are not removed. We have investigated the physiological basis of this inhibition in order to understand more about how lichen chemistry infiuences host preference in lichenicolous fungi. Results showed that the secondary compounds from L. papulosa inhibit the overall growth of M. corallimis, but not the catalytic activity of its tissue-degrading polysaccharidases. This effect is different from that shown by another lichen parasite, Nectria parmeliae, where lichen compounds specifically inhibited polysaccharidase activity. Compared with the compounds of L. papulosa, the endogenous phenolics of F. baltimorensis inhibited the growth of M. corallimis substantially less and exhibited little or no inhibition of polysaccharidases. For M. corallimis, host preference appears to be associated with physiological adaptation to the chemistry of F. baltimorensis.

scholarly journals Sephadex® LH-20, Isolation, and Purification of Flavonoids from Plant Species: A Comprehensive Review

Molecules ◽  
2020 ◽  
Vol 25 (18) ◽  
pp. 4146
Author(s):  
Javad Mottaghipisheh ◽  
Marcello Iriti
Keyword(s):  
Phenolic Compounds ◽  
Secondary Metabolites ◽  
Plant Species ◽  
Health Benefits ◽  
Significant Information ◽  
Comprehensive Review ◽  
Isolation And Purification ◽  
Phytochemical Investigation ◽  
Plant Families ◽  
Pure Methanol

Flavonoids are considered one of the most diverse phenolic compounds possessing several valuable health benefits. The present study aimed at gathering all correlated reports, in which Sephadex® LH-20 (SLH) has been utilized as the final step to isolate or purify of flavonoid derivatives among all plant families. Overall, 189 flavonoids have been documented, while the majority were identified from the Asteraceae, Moraceae, and Poaceae families. Application of SLH has led to isolate 79 flavonols, 63 flavones, and 18 flavanones. Homoisoflavanoids, and proanthocyanidins have only been isolated from the Asparagaceae and Lauraceae families, respectively, while the Asteraceae was the richest in flavones possessing 22 derivatives. Six flavones, four flavonols, three homoisoflavonoids, one flavanone, a flavanol, and an isoflavanol have been isolated as the new secondary metabolites. This technique has been able to isolate quercetin from 19 plant species, along with its 31 derivatives. Pure methanol and in combination with water, chloroform, and dichloromethane have generally been used as eluents. This comprehensive review provides significant information regarding to remarkably use of SLH in isolation and purification of flavonoids from all the plant families; thus, it might be considered an appreciable guideline for further phytochemical investigation of these compounds.

scholarly journals Bioactive Compounds from Brassicaceae: a Beneficial Contribution in our Everyday Diet

2011 ◽  
Vol 68 (2) ◽  
Author(s):  
Renato IORI ◽  
Gina R. DE NICOLA ◽  
Manuela BAGATTA ◽  
Eleonora PAGNOTTA
Keyword(s):  
Secondary Metabolites ◽  
Dietary Intake ◽  
Bioactive Compounds ◽  
Chemical Structure ◽  
Side Chain ◽  
Variable Part ◽  
Naturally Occurring ◽  
Interesting Class

Dietary intake of Brassicaceae (Crucifers) provides not only nutrients, but also a highly interesting class of secondary metabolites beneficial to health, known as glucosinolates (GLs). These compounds possess a -D-glucopyranosyl unit connected to a O-sulfated anomeric Z-thiohydroximate function, and a side chain R which is the only variable part of the chemical structure. Up to now, more than 120 naturally-occurring GLs have been carachterized

scholarly journals Industrial Automation using Zigbee Communication Protocol

2019 ◽  
Vol 8 (3) ◽  
pp. 7240-7243
Keyword(s):  
Wireless Communication ◽  
Ieee 802.11 ◽  
Industrial Application ◽  
Lower Cost ◽  
Communication Protocol ◽  
Industrial Applications ◽  
Video Content ◽  
Industrial Automation ◽  
Future Work ◽  
Wired Communication

If we compare wireless communication over wired communication, wireless communication offer more advantages when compared to wired communication such as lower cost, fast deployment, higher flexibility & scalability and mobile nature of system communicated wirelessly. In Industrial automation, industrial communication has very challenging requirements like packet deadline, low transmission jitter, etc. In some places wired communication is only accepted and it cannot be replaced by wireless communication. Industrial applications also run more flexible requirements applications such as email, Video content or any other application. Those services are known as Best Effort (BE) services. In order to do both the industrial application and BE services we have proposed Zigbee communication together with the IEEE 802.11 standard in this article along with comparison between the two standards using physical layer solutions. This Zigbee communication is performed using a industrial automation design and it leads to less power consumption. Result and analysis in terms of real time services is left as a future work in this paper. It is proposed that through Zigbee solution it is possible to obtain better result in certain cases than those achieved using IEEE 802.11 standards.

scholarly journals Secondary metabolites of a marine-derived Penicillium ochrochloron

2021 ◽  
Vol 13 (3) ◽  
pp. 11020
Author(s):  
Peter M. EZE ◽  
Ying GAO ◽  
Yang LIU ◽  
Lasse Van GEELEN ◽  
Chika P. EJIKEUGWU ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Secondary Metabolites ◽  
Biological Properties ◽  
Industrial Applications ◽  
Biologically Active ◽  
Fungal Isolation ◽  
The North ◽  
Wide Range ◽  
Extremophilic Fungi ◽  
Fungal Secondary Metabolites

Extremophilic fungi have received considerable attention recently as new promising sources of biologically active compounds with potential pharmaceutical applications. This study investigated the secondary metabolites of a marine-derived Penicillium ochrochloron isolated from underwater sea sand collected from the North Sea in St. Peter-Ording, Germany. Standard techniques were used for fungal isolation, taxonomic identification, fermentation, extraction, and isolation of fungal secondary metabolites. Chromatographic separation and spectroscopic analyses of the fungal secondary metabolites yielded eight compounds: talumarin A (1), aspergillumarin A (2), andrastin A (3), clavatol (4), 3-acetylphenol (5), methyl 2,5-dihydro-4-hydroxy-5-oxo-3-phenyl-2-furanpropanoate (6), emodin (7) and 2-chloroemodin (8). After co-cultivation with Bacillus subtilis, the fungus was induced to express (-)-striatisporolide A (9). Compound 1 was evaluated for antibacterial activity against Staphylococcus aureus, Acinetobacter baumannii, Mycobacterium smegmatis, and M. tuberculosis, as well as cytotoxicity against THP-1 cells. The compound, however, was not cytotoxic to THP-1 cells and had no antibacterial activity against the microorganisms tested. The compounds isolated from P. ochrochloron in this study are well-known compounds with a wide range of beneficial biological properties that can be explored for pharmaceutical, agricultural, or industrial applications. This study highlights the bioprospecting potential of marine fungi and confirms co-cultivation as a useful strategy for the discovery of new natural products.

Omphaloprenol A: A new bioactive polyisoprenepolyol isolated from the mycelium of poisonous mushroom Omphalotus japonicus

2021 ◽  
Author(s):  
Satoki Aoki ◽  
Takako Aboshi ◽  
Takumu Onodera ◽  
Ken-ichi Kimura ◽  
Daisuke Arai ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Secondary Metabolites ◽  
Bioactive Compounds ◽  
Chemical Structure ◽  
Lettuce Seeds ◽  
Illudin S ◽  
Poisonous Mushroom ◽  
Growth Promoting

Abstract Mushrooms of the Omphalotus genus are known to be rich in secondary metabolites. In the quest for new bioactive compounds, we analyzed the compounds isolated from the mycelium of the poisonous mushroom Omphalotus japonicus. As a result, a new polyisoprenepolyol, which was named omphaloprenol A, was identified, along with known substances such as hypsiziprenol A10 and A11, illudin S, and ergosterol. The chemical structure of omphaloprenol A was elucidated by nuclear magnetic resonance and infrared spectroscopies and mass spectrometry, and its bioactivity was investigated. Omphaloprenol A showed growth promoting activity against the root of lettuce seeds and cytotoxicity against HL60 cells. To the best of our knowledge, this is the first report on the isolation of a polyisoprenepolyol compound from Omphalotaceae mushrooms.

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