Lactobacillus casei-fermented blueberry pomace augments sIgA production in high-fat diet mice by improving intestinal microbiota

2020 ◽  
Vol 11 (7) ◽  
pp. 6552-6564
Author(s):  
Yuxin Cheng ◽  
Shuxin Tang ◽  
Yuting Huang ◽  
Fuqiang Liang ◽  
Yajing Fang ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
High Fat Diet ◽  
Lactobacillus Casei ◽  
Immunoglobulin A ◽  
Secretory Immunoglobulin A ◽  
High Fat ◽  
Secretory Immunoglobulin

Intestinal secretory immunoglobulin A (sIgA)-improving function of Lactobacillus casei-fermented blueberry pomace (FBP) was investigated in this study.

scholarly journals High-fat diet reduces the level of secretory immunoglobulin A coating of commensal gut microbiota

2019 ◽  
Vol 38 (2) ◽  
pp. 55-64 ◽  
Author(s):  
Teresia Aluoch MUHOMAH ◽  
Naoki NISHINO ◽  
Emiko KATSUMATA ◽  
Wu HAOMING ◽  
Takeshi TSURUTA
Keyword(s):  
Gut Microbiota ◽  
High Fat Diet ◽  
Immunoglobulin A ◽  
Secretory Immunoglobulin A ◽  
High Fat ◽  
Secretory Immunoglobulin

Intestinal microbiota and secretory immunoglobulin A in feces of exclusively breast-fed infants with blood-streaked stools

2012 ◽  
Vol 56 (10) ◽  
pp. 657-663 ◽  
Author(s):  
Hideki Kumagai ◽  
Shun-ichi Maisawa ◽  
Mamoru Tanaka ◽  
Motomichi Takahashi ◽  
Yuhei Takasago ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Immunoglobulin A ◽  
Secretory Immunoglobulin A ◽  
Breast Fed ◽  
Secretory Immunoglobulin

scholarly journals The immune landscape of IgA induction in the gut

2021 ◽  
Author(s):  
Claudia Seikrit ◽  
Oliver Pabst
Keyword(s):  
Protective Immunity ◽  
Immunoglobulin A ◽  
Antibody Responses ◽  
Dark Side ◽  
Secretory Immunoglobulin A ◽  
Antibody Isotype ◽  
Mucosal Antibody ◽  
Key Concepts ◽  
Basic Understanding ◽  
Secretory Immunoglobulin

AbstractAntibodies are key elements of protective immunity. In the mucosal immune system in particular, secretory immunoglobulin A (SIgA), the most abundantly produced antibody isotype, protects against infections, shields the mucosal surface from toxins and environmental factors, and regulates immune homeostasis and a peaceful coexistence with our microbiota. However, the dark side of IgA biology promotes the formation of immune complexes and provokes pathologies, e.g., IgA nephropathy (IgAN). The precise mechanisms of how IgA responses become deregulated and pathogenic in IgAN remain unresolved. Yet, as the field of microbiota research moved into the limelight, our basic understanding of IgA biology has been taking a leap forward. Here, we discuss the structure of IgA, the anatomical and cellular foundation of mucosal antibody responses, and current concepts of how we envision the interaction of SIgA and the microbiota. We center on key concepts in the field while taking account of both historic findings and exciting new observations to provide a comprehensive groundwork for the understanding of IgA biology from the perspective of a mucosal immunologist.

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