Stabilization and delivery of bioavailable nanosized iron by fish sperm DNA

2020 ◽  
Vol 11 (7) ◽  
pp. 6240-6250
Author(s):  
Shiyang Li ◽  
Jiayou Zhang ◽  
Yu Miao ◽  
Wei Guo ◽  
Guangxin Feng ◽  
...  

Nanosized iron is a promising candidate as an iron fortificant due to its good solubility and bioavailability.

2021 ◽  
pp. 088532822110504
Author(s):  
Faiza Sajjad ◽  
Yiping Han ◽  
Leilei Bao ◽  
Yijia Yan ◽  
Donal O shea ◽  
...  

Photodynamic therapy (PDT) is a promising new treatment for cancer; however, the hydrophobic interactions and poor solubility in water of photosensitizers limit the use in clinic. Nanoparticles especially carbon dots have attracted the attention of the world’s scientists because of their unique properties such as good solubility and biocompatibility. In this paper, we integrated carbon dots with different porphyrins to improve the properties of porphyrins and evaluated their efficacy as PDT drugs. The spectroscopic characteristics of porphyrins nano-conjugates were studied. Singlet oxygen generation rate and the light- and dark-induced toxicity of the conjugates were studied. Our results showed that the covalent interaction between CDs and porphyrins has improved the biocompatibility. The synthesized conjugates also inherit the pH sensitivity of the carbon dots, while the conjugation also decreases the hemolysis ratio making them a promising candidate for PDT. The incorporation of carbon dots into porphyrins improved their biocompatibility by reducing toxicity.


2008 ◽  
Vol 1094 ◽  
Author(s):  
Micha Jost ◽  
Petia Atanasova ◽  
Peter Gerstel ◽  
Wilfried Sigle ◽  
Peter A. van Aken ◽  
...  

AbstractIn this paper, a new and simple method for the synthesis of ZnO nanowires under very mild conditions is presented. The nanowire preparation is based on mineralization from alkaline aqueous zinc nitrate solution in the presence of fish sperm DNA as a structure-directing agent. The morphological features of the obtained structures were investigated by scanning electron microscopy (SEM) and transmission electron microscopy (TEM), while the structural characterization of ZnO was done by X-ray diffraction.


2012 ◽  
Vol 9 (3) ◽  
pp. 1587-1598 ◽  
Author(s):  
R. Hajian ◽  
E. Ekhlasi ◽  
R. Daneshvar

The interactions between epirubicin (EPR) and double stranded DNA (ds-DNA) have been studied by UV-Vis spectrophotometry, cyclic voltammetry, fluorescence spectroscopy and viscometery. The apparent binding constant of epirubicin with DNA was found to be 3.8 × 105mol-1L and was studied at different temperatures. It indicated that the former method could be successfully applied to the determination of epirubicin. Also, the voltammetric behavior of EPR was investigated at glassy carbon electrode using cyclic voltammetry. Thermodynamic parameters including ∆H0, ∆G0and ∆S0were determined as -5.7×104, -3.13×104J mol-1and -87.96 J mol-1K-1 respectively. One indication of the strong interaction between DNA and EP was increasing of viscosity. The diffusion coefficients of EP in the absence (D0)fand presence of ds-DNA (D0)bwas calculated as 5.04×10-6and 1.13×10-6 Cm2s-1respectively. According to the thermodynamic parameters, the main binding force could be judged. The experimental results revealed that EPR and ds-DNA had strong interactions. The mechanism of quenching belonged to static quenching and the main sort of binding force was intercalation.


Catalysts ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 552 ◽  
Author(s):  
M. Mart ◽  
W. Tylus ◽  
A. Trzeciak

Pd/DNA catalysts were prepared in a mixed H2O/EtOH solvent using palladium precursors, Pd(OAc)2 and PdCl2, in different dosages and salmon fish sperm DNA. As prepared, the Pd/DNA contained Pd(II) and Pd(0) nanoparticles of various sizes and morphologies, depending on the preparation method. Pd/DNA efficiently catalyzed the Suzuki–Miyaura cross-coupling of various aryl bromides with phenylboronic acids. The catalyst was recovered by simple phase separation and then reused in seven consecutive cycles with a high activity.


Luminescence ◽  
2016 ◽  
Vol 32 (4) ◽  
pp. 674-679 ◽  
Author(s):  
Yangfang Kuang ◽  
Sheng Liang ◽  
Fangfang Ma ◽  
Shu Chen ◽  
Yunfei Long ◽  
...  

Author(s):  
Chung-kook Lee ◽  
Yolande Berta ◽  
Robert F. Speyer

Barium hexaferrite (BaFe12O19) is a promising candidate for high density magnetic recording media due to its superior magnetic properties. For particulate recording media, nano-sized single crystalline powders with a narrow size distribution are a primary application requirement. The glass-crystallization method is preferred because of the controllability of crystallization kinetics, hence, particle size and size distribution. A disadvantage of this method is the need to melt raw materials at high temperatures with non-reactive crucibles, e.g. platinum. However, in this work, we have shown that crystal growth of barium hexaferrite occurred during low temperature heat treatment of raw batches.


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