Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways

2020 ◽  
Vol 11 (6) ◽  
pp. 5621-5634 ◽  
Author(s):  
Xiaoqi Wu ◽  
Mohammad Al-Amin ◽  
Chao Zhao ◽  
Fengping An ◽  
Yiwei Wang ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
Health Benefits ◽  
Biological Properties ◽  
Polyphenol Compound ◽  
Natural Polyphenol

Catechinic acid (CA), widely present in tea and fruits, has vital biological properties and health benefits.

MPA-capped CdTe quantum dots exposure causes neurotoxic effects in nematode Caenorhabditis elegans by affecting the transporters and receptors of glutamate, serotonin and dopamine at the genetic level, or by increasing ROS, or both

Nanoscale ◽  
2015 ◽  
Vol 7 (48) ◽  
pp. 20460-20473 ◽  
Author(s):  
Tianshu Wu ◽  
Keyu He ◽  
Qinglin Zhan ◽  
Shengjun Ang ◽  
Jiali Ying ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Caenorhabditis Elegans ◽  
Biomedical Applications ◽  
Biological Properties ◽  
Cdte Quantum Dots ◽  
Nematode Caenorhabditis Elegans ◽  
Neurotoxic Effects ◽  
Genetic Level

As quantum dots (QDs) are widely used in biomedical applications, the number of studies focusing on their biological properties is increasing.

In vivo assessment of polydatin, a natural polyphenol compound, on arsenic-induced free radical overproduction, gene expression, and genotoxicity

2017 ◽  
Vol 25 (3) ◽  
pp. 2614-2622 ◽  
Author(s):  
Damla Arslan-Acaroz ◽  
Fahriye Zemheri ◽  
Hasan Huseyin Demirel ◽  
Ismail Kucukkurt ◽  
Sinan Ince ◽  
...  
Keyword(s):  
Gene Expression ◽  
Free Radical ◽  
Polyphenol Compound ◽  
Natural Polyphenol ◽  
In Vivo Assessment

Ginkgo seed extract promotes longevity and stress resistance of Caenorhabditis elegans

2021 ◽  
Author(s):  
Nan Shen ◽  
Wen Zeng ◽  
Feng Leng ◽  
Jinkai Lu ◽  
Zhaogeng Lu ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
Stress Resistance ◽  
Health Benefits ◽  
Seed Extract ◽  
Traditional Food ◽  
Aging And Health ◽  
Health Promoting

Ginkgo seeds are a traditional food in China valued for their nutritional and health benefits. However, little is known about the anti-aging and health-promoting effects of ginkgo seed products. Here,...

scholarly journals In vitro biological properties and health benefits of a novel sulfated polysaccharide isolated from Cymodocea nodosa

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Rihab Ben Abdallah Kolsi ◽  
Bochra Gargouri ◽  
Sameh Sassi ◽  
Donyez Frikha ◽  
Saloua Lassoued ◽  
...  
Keyword(s):  
Health Benefits ◽  
Biological Properties ◽  
Sulfated Polysaccharide ◽  
Cymodocea Nodosa

Recent advances in elucidating the biological properties of Withania somnifera and its potential role in health benefits

2011 ◽  
Vol 11 (1) ◽  
pp. 97-112 ◽  
Author(s):  
Nadia Alam ◽  
Monzur Hossain ◽  
Md. Ibrahim Khalil ◽  
Mohammed Moniruzzaman ◽  
Siti Amrah Sulaiman ◽  
...  
Keyword(s):  
Withania Somnifera ◽  
Potential Role ◽  
Health Benefits ◽  
Biological Properties ◽  
Recent Advances

scholarly journals Ethnobotany, Phytochemical, Pharmacological Potentials of Murraya koenigii, and Its Health Benefits – A Review

2020 ◽  
pp. 29-38
Author(s):  
Priyanka Goyal ◽  
Rohit Chhabra ◽  
Lavanya Vij
Keyword(s):  
Therapeutic Potential ◽  
Health Benefits ◽  
Biological Properties ◽  
Review Article ◽  
Murraya Koenigii ◽  
Potential Health ◽  
Traditional Medicines ◽  
Whole Plant ◽  
Anti Oxidant ◽  
Anti Fungal

Murraya koenigii, also widely known as curry leaves and curry patta, is a noticeably significant plant recognized all around the world for its tremendous therapeutic, medicinal worth and characteristic aromatic properties. It is one of the major export commodities originated from east and southern part of India bringing good foreign revenue. This review article is designed to assess and compile all the currently available literature on ethnobotanical aspects and phytochemical, pharmacological potentials of M. koenigii. Morphologically, it is a semi deciduous small shrub or aromatic shrub having slender but strong woody stem with branches covered with grey bark. The whole plant of M. koenigii viz., as stem, leaf, fruits, root and seeds have been accounted to have anti-oxidant, anti-fungal, anti-candidal, anti-bacterial, anti-hypersensitive and various biological properties. It is also additionally used in hormonal therapy in traditional medicines as a dysenteric, blood purifier, diuretic, febrifuge, hair tonic, anti-inflammatory, analgesic, antipyretic and anti-diarrheal. M. koenigii oil is said to have massive impact in the pharmaceuticals and in aromatherapy enterprises as a powerful ingredient. Many researchers have worked on all parts of M. koenigii, from roots, stem, leaves up its bark. This review is an attempt to summarize all the diverse literature available so as to compile a reliable review article on M. koenigii providing detailed information on therapeutic potential, health benefits and pharmacological applications of the plant.

scholarly journals Potential Health Benefits of Origanum heracleoticum Essential Oil: Phytochemical and Biological Variability among Different Calabrian Populations

2018 ◽  
Vol 13 (9) ◽  
pp. 1934578X1801300 ◽  
Author(s):  
Mariangela Marrelli ◽  
Fabrizio Araniti ◽  
Maria Rosa Abenavoli ◽  
Giancarlo Statti ◽  
Filomena Conforti
Keyword(s):  
Essential Oils ◽  
Health Benefits ◽  
Hierarchical Cluster ◽  
Inhibitory Effect ◽  
Biological Properties ◽  
In Vitro Assays ◽  
No Production ◽  
Potential Health ◽  
Phytochemical Content

The potential health benefits of the essential oils of six different populations of Origanum heracleoticum L. from Calabria (Italy) were assessed, together with the evaluation of the influence of the site of collection on their metabolic profile and biological activity. Different terpenoids were identified, being thymol, carvacrol and o-cymene among the most abundant ones. Hierarchical cluster analysis allowed the identification of two main groups, which were discriminated by the altitude of collection. The antioxidant activity was tested by means of two in vitro assays: DPPH and β-carotene bleaching test. Samples EO-4 and EO-3 were the most active in protecting linoleic acid from peroxidation, with IC50 values of 4.00 and 4.68 μg/mL after 30 minutes of incubation. The anti-inflammatory potential was assessed through the evaluation of the capacity to inhibit NO production in lipopolysaccharide (LPS)-induced murine macrophage RAW 264.7 cell line. All essential oils induced a dose-depending inhibitory effect. An excellent activity was demonstrated for sample EO-4, followed by sample EO-3 (IC50 values equal to 32.77 and 49.48 μg/mL, respectively). Observed biological properties were correlated to the phytochemical content of analyzed samples.

Functional Food with some Health Benefits are so Called as Superfood-A Review

2020 ◽  
Vol 16 ◽  
Author(s):  
Ena Gupta ◽  
Pragya Mishra
Keyword(s):  
Functional Foods ◽  
Emotional Health ◽  
Health Benefits ◽  
Biological Properties ◽  
Human Case ◽  
Health Claims ◽  
Potential Health ◽  
Bioactive Ingredients ◽  
Conventional Foods ◽  
New Research

: The possible beneficial properties of functional foods are due to their content in bioactive ingredients, with specific biological properties. A number of processed functional foods are available in the market – probiotic yogurt, calcium and ω-3 fatty acids enriched orange juice and milk. Simultaneously, new research studies confer potential health benefits of various conventional foods (salmon, berries, green tea, vegetables, fruits, nuts, cereals and breads etc) termed as “superfood” which is a marketing term and there is no established medical definition. Following suitable dietary patterns superfood reduces the risk of degerative diseases by promoting physical and emotional health. Scientific evidences suggests that superfood are dense source of antioxidants, minerals, vitamins and other nutrients. There is insufficient research on the exact explanation of term ‘superfood’and its health claims by different companies without any legislation. This buzz word making confusion among consumers, that how much and what quantity should make a food superfood, as no single food may be as nutritious to be stated as superfood. This article introduces further investigation on superfood which was categorized on the basis of their major constituents and potential health benefits. Further there is a need of more reviews, researches, clinical trials and human case studies to investigate or test superfood.

scholarly journals Preparation, Characterization, and Release Kinetics of Chitosan-Coated Nanoliposomes Encapsulating Curcumin in Simulated Environments

Molecules ◽  
2019 ◽  
Vol 24 (10) ◽  
pp. 2023 ◽  
Author(s):  
Mahmoud Hasan ◽  
Kamil Elkhoury ◽  
Cyril J. F. Kahn ◽  
Elmira Arab-Tehrany ◽  
Michel Linder
Keyword(s):  
Release Kinetics ◽  
Physicochemical Characteristics ◽  
Biological Properties ◽  
Lipophilic Compounds ◽  
Simulated Environments ◽  
Natural Polyphenol ◽  
Poorly Soluble ◽  
The Stability ◽  
Kinetics Of ◽  
Low Solubility

Curcumin, a natural polyphenol, has many biological properties, such as anti-inflammatory, antioxidant, and anti-carcinogenic properties, yet, its sensitivity to light, oxygen, and heat, and its low solubility in water renders its preservation and bioavailability challenging. To increase its bioaccessibility, we fabricated nanoliposomes and chitosan-coated nanoliposomes encapsulating curcumin, and we evaluated the systems in terms of their physicochemical characteristics and release profiles in simulated gastrointestinal mediums. Chitosan-coating enhanced the stability of nanoliposomes and slowed the release of curcumin in the simulated gastrointestinal (GI) environment. This study demonstrates that nanoliposomes and chitosan-coated nanoliposomes are promising carriers for poorly soluble lipophilic compounds with low oral bioavailability, such as curcumin.

scholarly journals Counteracting Cisplatin-Induced Testicular Damages by Natural Polyphenol Constituent Honokiol

Antioxidants ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. 723
Author(s):  
Tse-En Wang ◽  
Yu-Hua Lai ◽  
Kai-Chien Yang ◽  
Sung-Jan Lin ◽  
Chih-Lin Chen ◽  
...  
Keyword(s):  
Type I Collagen ◽  
Type I ◽  
Dna Breaks ◽  
Gene Expressions ◽  
Beneficial Effects ◽  
Polyphenol Compound ◽  
Anti Cancer ◽  
Natural Polyphenol

Cisplatin, despite its anti-cancer ability, exhibits severe testicular toxicities when applied systemically. Due to its wide application in cancer treatment, reduction of its damages to normal tissue is an imminent clinical need. Here we evaluated the effects of honokiol, a natural lipophilic polyphenol compound, on cisplatin-induced testicular injury. We showed in-vitro and in-vivo that nanosome-encapsulated honokiol attenuated cisplatin-induced DNA oxidative stress by suppressing intracellular reactive oxygen species production and elevating gene expressions of mitochondrial antioxidation enzymes. Nanosome honokiol also mitigated endoplasmic reticulum stress through down regulation of Bip-ATF4-CHOP signaling pathway. Additionally, this natural polyphenol compound diminished cisplatin-induced DNA breaks and cellular apoptosis. The reduced type I collagen accumulation in the testis likely attributed from inhibition of TGFβ1, αSMA and ER protein TXNDC5 protein expression. The combinatorial beneficial effects better preserve spermatogenic layers and facilitate repopulation of sperm cells. Our study renders opportunity for re-introducing cisplatin to systemic anti-cancer therapy with reduced testicular toxicity and restored fertility.

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