Effect of rhamnolipid biosurfactant on transport and retention of iron oxide nanoparticles in water-saturated quartz sand

2021 ◽  
Author(s):  
Shuchi Liao ◽  
Anushree Ghosh ◽  
Matthew D. Becker ◽  
Linda M. Abriola ◽  
Natalie L. Cápiro ◽  
...  
Keyword(s):  
Mathematical Modeling ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Quartz Sand ◽  
Column Experiments ◽  
Oxide Nanoparticles ◽  
The Stability ◽  
Rhamnolipid Biosurfactant ◽  
Water Saturated

Column experiments and mathematical modeling results demonstrated that rhamnolipid biosurfactant can enhance the stability and mobility of iron oxide nanoparticles in water-saturated quartz sand.

The Effect of Time on the Stability of Iron Oxide Nanoparticles in Environmental Acids

2017 ◽  
Vol 89 (5) ◽  
pp. 416-423 ◽  
Author(s):  
Anna Rabajczyk ◽  
Naouale El Yamani ◽  
Maria Dusinska
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
The Stability

scholarly journals Biocompatible Layers Obtained from Functionalized Iron Oxide Nanoparticles in Suspension

Coatings ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 773 ◽  
Author(s):  
Daniela Predoi ◽  
Simona Liliana Iconaru ◽  
Mihai Valentin Predoi ◽  
Nicolas Buton ◽  
Christelle Megier ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Hydrodynamic Diameter ◽  
Oxide Nanoparticles ◽  
Characterization Methods ◽  
Sem Image ◽  
Stable Suspension ◽  
Cytotoxicity Studies ◽  
Ultrasound Measurements ◽  
The Stability

Iron oxide nanoparticles have been extensively studied for challenges in applicable areas such as medicine, pharmacy, and the environment. The functionalization of iron oxide nanoparticles with dextran opens new prospects for application. Suspension characterization methods such as dynamic light scattering (DLS) and zeta potential (ZP) have allowed us to obtain information regarding the stability and hydrodynamic diameter of these suspended particles. For rigorous characterization of the suspension of dextran-coated iron oxide nanoparticles (D-MNPs), studies have been performed using ultrasound measurements. The results obtained from DLS and ZP studies were compared with those obtained from ultrasound measurements. The obtained results show a good stability of D-MNPs. A comparison between the D-MNP dimension obtained from transmission electron microscopy (TEM), X-ray diffraction (XRD), and DLS studies was also performed. A scanning electron spectroscopy (SEM) image of a surface D-MNP layer obtained from the stable suspension shows that the particles are spherical in shape. The topographies of the elemental maps of the D-MNP layer showed a uniform distribution of the constituent elements. The homogeneity of the layer was also observed. The morphology of the HeLa cells incubated for 24 and 48 h with the D-MNP suspension and D-MNP layers did not change relative to the morphology presented by the control cells. The cytotoxicity studies conducted at different time intervals have shown that a slight decrease in the HeLa cell viability after 48 h of incubation for both samples was observed.

Quince Seed Mucilage Coated Iron Oxide Nanoparticles for Plasmid DNA Delivery

2021 ◽  
Author(s):  
bahar Nikforouz ◽  
alireza allafchian ◽  
Seyed Amir Hossein Jalali ◽  
Hamideh Shakeripour ◽  
Rezvan Mohammadinezhad
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Plasmid Dna ◽  
Low Cost ◽  
Magnetic Hysteresis ◽  
Oxide Nanoparticles ◽  
Ft Ir ◽  
The Stability ◽  
Xrd Patterns ◽  
Seed Mucilage

Abstract This study investigates the potential of iron oxide nanoparticles (Fe3O4) and quince seed mucilage (QSM) as combined genetic carriers to deliver plasmid DNA (pDNA) through the gastrointestinal system. The samples are characterized by XRD, zeta potential, DLS, FT-IR spectroscopy, FE-SEM and VSM. The stability of pDNA loading on the nanocarriers and their release pattern are evaluated in simulated gastrointestinal environments by electrophoresis. The XRD patterns reveal that the nanocarriers could preserve their structure during various synthesis levels. The saturation magnetization (Ms) of the Fe3O4 cores are 56.48 emu/g without any magnetic hysteresis. Not only does the loaded pDNA contents experience a remarkable stability in the simulated gastric environment, but also, they could be released up to 99% when exposed to an alkaline environment similar to the intestinal fluid of fish. The results indicate that the synthesized nanoparticles could be employed as efficient low-cost pDNA carriers.

scholarly journals Silica-Coated Magnetic Iron Oxide Nanoparticles Grafted onto Graphene Oxide for Protein Isolation

Nanomaterials ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 117 ◽  
Author(s):  
Xuan-Hung Pham ◽  
Eunil Hahm ◽  
Hyung-Mo Kim ◽  
Byung Sung Son ◽  
Ahla Jo ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Silica Layer ◽  
Protein Isolation ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Iron Oxide ◽  
The Stability ◽  
Epoxy Groups

In this study, silica-coated magnetic iron oxide nanoparticles (MNPs@SiO2) were covalently conjugated onto graphene oxide (GO/MNP@SiO2) for protein isolation. First, MNPs were precisely coated with a silica layer on the surface by using the reverse microemulsion method, followed by incubation with 3-glycidyloxypropyltrimethoxysilane (GPTS) to produce the GPTS-functionalized MNPs@SiO2 (GPTS-coated MNPs@SiO2) that display epoxy groups on the surface. The silica shell on the MNPs was optimized at 300 µL of Igepal®CO-520, 5 mg of MNP, 100 µL of TEOS, 100 µL of NH4OH and 3% of 3-glycidyloxypropyltrimethoxysilane (GPTS). Simultaneously, polyethyleneimine (PEI) was covalently conjugated to GO to enhance the stability of GO in aqueous solutions and create the reaction sites with epoxy groups on the surface of GPTS-coated MNP@SiO2. The ratio of PEI grafted GO and GPTS-coated MNP@SiO2 (GO/MNP ratio) was investigated to produce GO/MNPs@SiO2 with highly saturated magnetization without aggregation. As a result, the GO/MNP ratio of 5 was the best condition to produce the GO/MNP@SiO2 with 9.53 emu/g of saturation superparamagnetization at a magnetic field of 2.0 (T). Finally, the GO/MNPs@SiO2 were used to separate bovine serum albumin (BSA) to investigate its protein isolation ability. The quantity of BSA adsorbed onto 1 mg of GO/MNP@SiO2 increased sharply over time to reach 628 ± 9.3 µg/mg after 15 min, which was 3.5-fold-higher than that of GPTS-coated MNP@SiO2. This result suggests that the GO/MNP@SiO2 nanostructure can be used for protein isolation.

TARGETING CYCLIN B1 WITH ANTISENSE OLIGONUCLETOTIDES- COATED SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES

2018 ◽  
Vol 6 (10) ◽  
Author(s):  
Hosam Zaghloul ◽  
Doaa A. Shahin ◽  
Ibrahim El- Dosoky ◽  
Mahmoud E. El-awady ◽  
Fardous F. El-Senduny ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Cellular Uptake ◽  
Superparamagnetic Iron Oxide ◽  
Cyclin B1 ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Mcf7 Cells ◽  
M Phase ◽  
The Impact

Antisense oligonucleotides (ASO) represent an attractive trend as specific targeting molecules but sustain poor cellular uptake meanwhile superparamagnetic iron oxide nanoparticles (SPIONs) offer stability of ASO and improved cellular uptake. In the present work we aimed to functionalize SPIONs with ASO targeting the mRNA of Cyclin B1 which represents a potential cancer target and to explore its anticancer activity. For that purpose, four different SPIONs-ASO conjugates, S-M (1–4), were designated depending on the sequence of ASO and constructed by crosslinking carboxylated SPIONs to amino labeled ASO. The impact of S-M (1–4) on the level of Cyclin B1, cell cycle, ROS and viability of the cells were assessed by flowcytometry. The results showed that S-M3 and S-M4 reduced the level of Cyclin B1 by 35 and 36%, respectively. As a consequence to downregulation of Cyclin B1, MCF7 cells were shown to be arrested at G2/M phase (60.7%). S-M (1–4) led to the induction of ROS formation in comparison to the untreated control cells. Furthermore, S-M (1–4) resulted in an increase in dead cells compared to the untreated cells and SPIONs-treated cells. In conclusion, targeting Cyclin B1 with ASO-coated SPIONs may represent a specific biocompatible anticancer strategy.

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