Clay-catalyzed ozonation of endocrine-disrupting compounds in solvent-free media – to better understand soil catalytic capacity

2020 ◽  
Vol 49 (46) ◽  
pp. 16693-16706
Author(s):  
Farida Boudissa ◽  
Meriem Zekkari ◽  
Vasilica-Alisa Arus ◽  
Rachida Ouargli-Saker ◽  
Bouazizi Nabil ◽  
...  
Keyword(s):  
Endocrine Disrupting Compounds ◽  
Surface Interaction ◽  
Solvent Free ◽  
Endocrine Disrupting ◽  
Hydrophilic Character ◽  
Free Media ◽  
Original Approach ◽  
Clay Catalysts ◽  
Catalytic Capacity

An original approach never followed so far allowed correlating the basicity and hydrophilic character of clay catalysts with surface interaction with 17α-Ethinylestradiol (EE2) during ozonation in water.

Nanofiltration of endocrine disrupting compounds

2003 ◽  
Vol 3 (5-6) ◽  
pp. 321-327 ◽  
Author(s):  
M. Gallenkemper ◽  
T. Wintgens ◽  
T. Melin
Keyword(s):  
Wastewater Treatment ◽  
Municipal Wastewater ◽  
Wastewater Treatment Plants ◽  
Endocrine Disrupting Compounds ◽  
Municipal Wastewater Treatment ◽  
Water And Wastewater Treatment ◽  
Wide Range ◽  
Endocrine Disrupting ◽  
Municipal Wastewater Treatment Plants ◽  
Set Up

Endocrine disrupting compounds can affect the hormone system in organisms. A wide range of endocrine disrupters were found in sewage and effluents of municipal wastewater treatment plants. Toxicological evaluations indicate that conventional wastewater treatment plants are not able to remove these substances sufficiently before disposing effluent into the environment. Membrane technology, which is proving to be an effective barrier to these substances, is the subject of this research. Nanofiltration provides high quality permeates in water and wastewater treatment. Eleven different nanofiltration membranes were tested in the laboratory set-up. The observed retention for nonylphenol (NP) and bisphenol A (BPA) ranged between 70% and 100%. The contact angle is an indicator for the hydrophobicity of a membrane, whose influence on the permeability and retention of NP was evident. The retention of BPA was found to be inversely proportional to the membrane permeability.

scholarly journals Design of a New Gemini Lipoaminoacid with Immobilized Lipases Based on an Eco-Friendly Biosynthetic Process

Catalysts ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 164
Author(s):  
Patrícia M. Carvalho ◽  
Rita C. Guedes ◽  
Maria R. Bronze ◽  
Célia M. C. Faustino ◽  
Maria H. L. Ribeiro
Keyword(s):  
High Performance ◽  
Transfection Efficiency ◽  
Sol Gel ◽  
Reaction Rates ◽  
Solvent Free ◽  
Bioactive Molecules ◽  
Thermomyces Lanuginosus ◽  
Chemical Production ◽  
Immobilized Lipases ◽  
Free Media

Lipoaminoacids (LAA) are an important group of biosurfactants, formed by a polar hydrophilic part (amino acid) and a hydrophobic tail (lipid). The gemini LAA structures allow the formation of a supramolecular complex with bioactive molecules, like DNA, which provides them with good transfection efficiency. Since lipases are naturally involved in lipid and protein metabolism, they are an alternative to the chemical production of LAA, offering an eco-friendly biosynthetic process option. This work aimed to design the production of novel cystine derived gemini through a bioconversion system using immobilized lipases. Three lipases were used: porcine pancreatic lipase (PPL); lipase from Thermomyces lanuginosus (TLL); and lipase from Rizhomucor miehei (RML). PPL was immobilized in sol-gel lenses. L-cystine dihydrochloride and dodecylamine were used as substrates for the bioreaction. The production of LAA was evaluated by thin layer chromatography (TLC), and colorimetric reaction with eosin. The identification and quantification was carried out by High Performance Liquid Chromatographer-Mass Spectrometry (HPLC-MS/MS). The optimization of media design included co-solvent (methanol, dimethylsulfoxide), biphasic (n-hexane and 2-propanol) or solvent-free media, in order to improve the biocatalytic reaction rates and yields. Moreover, a new medium was tested where dodecylamine was melted and added to the cystine and to the biocatalyst, building a system of mainly undissolved substrates, leading to 5 mg/mL of LAA. Most of the volume turned into foam, which indicated the production of the biosurfactant. For the first time, the gemini derived cystine lipoaminoacid was produced, identified, and quantified in both co-solvent and solvent-free media, with the lipases PPL, RML, and TLL.

scholarly journals Effects of the Hedgehog signalling inhibitor itraconazole on developing rat ovaries

2021 ◽  
Author(s):  
Hanna Katarina Lilith Johansson ◽  
Camilla Taxvig ◽  
Gustav Peder Mohr Olsen ◽  
Terje Svingen
Keyword(s):  
Endocrine Disrupting Chemicals ◽  
Endocrine Disrupting Compounds ◽  
Perinatal Period ◽  
Endocrine Function ◽  
Ovary Development ◽  
Knock Out ◽  
Female Reproductive Health ◽  
Endocrine Disrupting ◽  
Hh Signaling ◽  
Knock Out Mice

Abstract Early ovary development is considered to be largely hormone independent, yet there are associations between fetal exposure to endocrine disrupting chemicals and reproductive disorders in women. This can potentially be explained by perturbations to establishment of ovarian endocrine function rather than interference with an already established hormone system. In this study we explore if Hedgehog (HH) signaling, a central pathway for correct ovary development, can be disrupted by exposure to HH-disrupting chemicals, using the antifungal itraconazole as model compound. In the mouse Leydig cell line TM3, used as a proxy for ovarian theca cells, itraconazole exposure had a suppressing effect on genes downstream of HH signaling, such as Gli1. Exposing explanted rat ovaries (gestational day 22 or postnatal day 3) to 30 µM itraconazole for 72 h induced significant suppression of genes in the HH signaling pathway with altered Ihh, Gli1, Ptch1, and Smo expression similar to those previously observed in Ihh/Dhh knock-out mice. Exposing rat dams to 50 mg/kg bw/day in the perinatal period did not induce observable changes in the offspring’s ovaries. Overall, our results suggest that HH signal disruptors may affect ovary development with potential long-term consequences for female reproductive health. However, potent HH inhibitors would likely cause severe teratogenic effects at doses lower than those causing ovarian dysgenesis, so the concern with respect to reproductive disorder is for the presence of HH disruptors at low concentration in combination with other ovary or endocrine disrupting compounds.

scholarly journals Preparation of Al/Fe-PILC clay catalysts from concentrated precursors: enhanced hydrolysis of pillaring metals and intercalation

RSC Advances ◽  
2020 ◽  
Vol 10 (66) ◽  
pp. 40450-40460
Author(s):  
Carlos Andrés Vallejo ◽  
Luis Alejandro Galeano ◽  
Raquel Trujillano ◽  
Miguel Ángel Vicente ◽  
Antonio Gil
Keyword(s):  
Solvent Free ◽  
Peroxide Oxidation ◽  
Highly Active ◽  
Wet Peroxide Oxidation ◽  
Catalytic Wet Peroxide Oxidation ◽  
Hydrolysis Of ◽  
Clay Catalysts

Significantly intensified preparation of Al/Fe-hydrolysed-pillaring solutions and solvent-free intercalation of bentonites yielding Al/Fe-PILCs highly active in catalytic wet peroxide oxidation.

Automatic flow-through system for exploration of the human bioaccessibility of endocrine disrupting compounds from microplastics

The Analyst ◽  
2021 ◽  
Author(s):  
Manuel Miro ◽  
Alexandra Sixto ◽  
Bilal El-Morabit ◽  
María José Trujillo-Rodríguez ◽  
Enrique Javier Carrasco-Correa
Keyword(s):  
Endocrine Disrupting Compounds ◽  
Gi Tract ◽  
Endocrine Disrupting ◽  
Flow Through

This article reports on the first attempt towards investigating the leaching rates in the human gastrointestinal (GI) tract of plastic-borne contaminants that can be ingested accidentally using physiologically relevant body...

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