scholarly journals Recent advances in iron-complexes as drug candidates for cancer therapy: reactivity, mechanism of action and metabolites

2020 ◽  
Vol 49 (33) ◽  
pp. 11451-11466
Author(s):  
Mathilde Bouché ◽  
Cécilia Hognon ◽  
Stéphanie Grandemange ◽  
Antonio Monari ◽  
Philippe C. Gros
Keyword(s):  
Cancer Therapy ◽  
Mechanism Of Action ◽  
Cellular Localization ◽  
Iron Homeostasis ◽  
Iron Complexes ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Drug Candidates ◽  
Structure Activity ◽  
Recent Advances

In this perspective, we discuss iron-complexes as drug candidates, and emphasize breakthroughs in the comprehension of their structure–activity relationship, metabolization pathways, sub-cellular localization and influence on iron homeostasis.

scholarly journals Progress on lamellarins

MedChemComm ◽  
2011 ◽  
Vol 2 (8) ◽  
pp. 689-697 ◽  
Author(s):  
Daniel Pla ◽  
Fernando Albericio ◽  
Mercedes Álvarez
Keyword(s):  
Mechanism Of Action ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity

The latest developments towards the synthesis of lamellarins, their structure–activity relationship and advances in the mechanism of action are described.

scholarly journals Cellular Localization of Dieldrin and Structure–Activity Relationship of Dieldrin Analogues in Dopaminergic Cells

2013 ◽  
Vol 26 (7) ◽  
pp. 1043-1054 ◽  
Author(s):  
Erin M. G. Allen ◽  
Virginia R. Florang ◽  
Laurie L. Davenport ◽  
Yunden Jinsmaa ◽  
Jonathan A. Doorn
Keyword(s):  
Cellular Localization ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Dopaminergic Cells ◽  
Structure Activity ◽  
Relationship Of

Antioxidant properties of phenolic Schiff bases: structure–activity relationship and mechanism of action

2013 ◽  
Vol 27 (11) ◽  
pp. 951-964 ◽  
Author(s):  
El Hassane Anouar ◽  
Salwa Raweh ◽  
Imene Bayach ◽  
Muhammad Taha ◽  
Mohd Syukri Baharudin ◽  
...  
Keyword(s):  
Schiff Bases ◽  
Mechanism Of Action ◽  
Antioxidant Properties ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity

scholarly journals Structure−Activity Relationship and Mechanism of Action Studies of Manzamine Analogues for the Control of Neuroinflammation and Cerebral Infections

2010 ◽  
Vol 53 (1) ◽  
pp. 61-76 ◽  
Author(s):  
Jiangnan Peng ◽  
Sucheta Kudrimoti ◽  
Sivaprakasam Prasanna ◽  
Srinivas Odde ◽  
Robert J. Doerksen ◽  
...  
Keyword(s):  
Mechanism Of Action ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Cerebral Infections
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