Combating metastasis of breast cancer cells with a carboplatin analogue containing an all-trans retinoic acid ligand

2020 ◽  
Vol 49 (16) ◽  
pp. 5039-5043
Author(s):  
Yi Dai ◽  
Hai Huang ◽  
Yang Zhu ◽  
Junjie Cheng ◽  
Ai-Zong Shen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Retinoic Acid ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Tumor Metastasis ◽  
Click Reaction ◽  
Dual Function ◽  
Acid Ligand ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid

Pt-ATRA, a carboplatin analogue containing an all-trans retinoic acid (ATRA) derivative ligand, was synthesized via a click reaction. Pt-ATRA demonstrates dual function by inducing cell apoptosis and inhibiting tumor metastasis.

scholarly journals MicroRNA networks regulated by all-trans retinoic acid and Lapatinib control the growth, survival and motility of breast cancer cells

Oncotarget ◽  
2015 ◽  
Vol 6 (15) ◽  
pp. 13176-13200 ◽  
Author(s):  
James Neil Fisher ◽  
Mineko Terao ◽  
Maddalena Fratelli ◽  
Mami Kurosaki ◽  
Gabriela Paroni ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Retinoic Acid ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid ◽  
Microrna Networks
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