scholarly journals Nucleic acid constructs for the interrogation of multivalent protein interactions

2020 ◽  
Vol 49 (19) ◽  
pp. 6848-6865 ◽  
Author(s):  
Sean B. Yeldell ◽  
Oliver Seitz
Keyword(s):  
Nucleic Acid ◽  
Protein Interactions ◽  
Self Assembly ◽  
Acid Ligand ◽  
Protein Receptors

Sequence-programmed self-assembly provides multivalent nucleic acid–ligand constructs used as tailor-made probes for unravelling and exploiting the mechanisms of multivalency-enhanced interactions on protein receptors.

Partial Purification of a Specific Plasminogen Activator from Porcine Parotid Glands

1974 ◽  
Vol 31 (03) ◽  
pp. 403-414 ◽  
Author(s):  
Terence Cartwright
Keyword(s):  
Nucleic Acid ◽  
Salivary Glands ◽  
Plasminogen Activator ◽  
Protein Interactions ◽  
Partial Purification ◽  
Protein Protein Interactions ◽  
Parotid Glands ◽  
Two Stage ◽  
Preliminary Characterization ◽  
Specific Inhibitors

SummaryA method is described for the extraction with buffers of near physiological pH of a plasminogen activator from porcine salivary glands. Substantial purification of the activator was achieved although this was to some extent complicated by concomitant extraction of nucleic acid from the glands. Preliminary characterization experiments using specific inhibitors suggested that the activator functioned by a similar mechanism to that proposed for urokinase, but with some important kinetic differences in two-stage assay systems. The lack of reactivity of the pig gland enzyme in these systems might be related to the tendency to protein-protein interactions observed with this material.

Self-assembly of nanostructures with multiferroic components using nucleic acid linkers

2016 ◽  
Vol 7 (1) ◽  
pp. 20-26 ◽  
Author(s):  
Ferman A. Chavez ◽  
Gopalan Srinivasan
Keyword(s):  
Nucleic Acid ◽  
Self Assembly ◽  
Image Position

Abstract

Synthesis, Characterization, Investigation of Capacitance and Redox Properties of Self-assembled Phe-Phe with Ferrocene Conjugates

2021 ◽  
Author(s):  
Om Shanker Tiwari
Keyword(s):  
Nucleic Acid ◽  
Electrochemical Properties ◽  
Self Assembly ◽  
Peptide Nucleic Acid ◽  
Redox Properties ◽  
Self Assembled ◽  
Acid Unit

The synthesis, nanostructure self-assembly and electrochemical properties of a series of ferrocene conjugated peptides derived from the dipeptide Phe-Phe, nucleoside and the peptide nucleic acid unit which are covalently attached...

Detection of nucleic acid–protein interactions in plant leaves using fluorescence lifetime imaging microscopy

2017 ◽  
Vol 12 (9) ◽  
pp. 1933-1950 ◽  
Author(s):  
Laurent Camborde ◽  
Alain Jauneau ◽  
Christian Brière ◽  
Laurent Deslandes ◽  
Bernard Dumas ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Fluorescence Lifetime ◽  
Protein Interactions ◽  
Fluorescence Lifetime Imaging Microscopy ◽  
Fluorescence Lifetime Imaging ◽  
Plant Leaves ◽  
Lifetime Imaging ◽  
Acid Protein

ChemInform Abstract: Nucleic Acid Encoding to Program Self-Assembly in Chemical Biology

ChemInform ◽  
2008 ◽  
Vol 39 (41) ◽  
Author(s):  
Zbigniew L. Pianowski ◽  
Nicolas Winssinger
Keyword(s):  
Nucleic Acid ◽  
Self Assembly ◽  
Chemical Biology

Zwitterionic polypeptides bearing carboxybetaine and sulfobetaine: synthesis, self-assembly, and their interactions with proteins

2018 ◽  
Vol 9 (10) ◽  
pp. 1178-1189 ◽  
Author(s):  
Yu-Lin Tsai ◽  
Yu-Chao Tseng ◽  
Yan-Miao Chen ◽  
Tain-Ching Wen ◽  
Jeng-Shiung Jan
Keyword(s):  
Protein Interactions ◽  
Self Assembly

Zwitterionic polypeptides bearing carboxybetaine and sulfobetaine were synthesized and their self-assembly and protein interactions were evaluated.

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