Protobranching as repulsion-induced attraction: a prototype for geminal stabilization

2020 ◽  
Vol 22 (29) ◽  
pp. 16998-17006
Author(s):  
Justin P. Joyce ◽  
Matthew P. Shores ◽  
Anthony K. Rappè
Keyword(s):  
Complete Understanding ◽  
Exchange Repulsion

The complementarity of overlap-induced exchange repulsion and electron correlative dispersion suggests that each is important to a complete understanding of branched hydrocarbon stability.

Conformation of Ribosomes from Escherichia Coli

1974 ◽  
Vol 32 ◽  
pp. 210-211
Author(s):  
M. Boublik ◽  
W. Hellmann ◽  
F. Jenkins
Keyword(s):  
Binding Sites ◽  
Ribosomal Proteins ◽  
Fluorescent Dyes ◽  
Protein Biosynthesis ◽  
Three Dimensional ◽  
Spatial Arrangement ◽  
Dimensional Structure ◽  
Complete Understanding ◽  
And Function

The present knowledge of the three-dimensional structure of ribosomes is far too limited to enable a complete understanding of the various roles which ribosomes play in protein biosynthesis. The spatial arrangement of proteins and ribonuclec acids in ribosomes can be analysed in many ways. Determination of binding sites for individual proteins on ribonuclec acid and locations of the mutual positions of proteins on the ribosome using labeling with fluorescent dyes, cross-linking reagents, neutron-diffraction or antibodies against ribosomal proteins seem to be most successful approaches. Structure and function of ribosomes can be correlated be depleting the complete ribosomes of some proteins to the functionally inactive core and by subsequent partial reconstitution in order to regain active ribosomal particles.

The Nature of Oxide Surfaces: Topographic and Electronic Structure

1993 ◽  
Vol 51 ◽  
pp. 966-967
Author(s):  
Dawn A. Bonnell ◽  
Yong Liang
Keyword(s):  
Transition Metal Oxides ◽  
Electronic Structures ◽  
Recent Progress ◽  
Spatial Localization ◽  
Level Of Detail ◽  
Scanning Tunneling ◽  
Oxide Surfaces ◽  
Tunneling Microscopy ◽  
Considerable Effort ◽  
Complete Understanding

Recent progress in the application of scanning tunneling microscopy (STM) and tunneling spectroscopy (STS) to oxide surfaces has allowed issues of image formation mechanism and spatial resolution limitations to be addressed. As the STM analyses of oxide surfaces continues, it is becoming clear that the geometric and electronic structures of these surfaces are intrinsically complex. Since STM requires conductivity, the oxides in question are transition metal oxides that accommodate aliovalent dopants or nonstoichiometry to produce mobile carriers. To date, considerable effort has been directed toward probing the structures and reactivities of ZnO polar and nonpolar surfaces, TiO2 (110) and (001) surfaces and the SrTiO3 (001) surface, with a view towards integrating these results with the vast amount of previous surface analysis (LEED and photoemission) to build a more complete understanding of these surfaces. However, the spatial localization of the STM/STS provides a level of detail that leads to conclusions somewhat different from those made earlier.

Meta-Accuracy and Perceived Reciprocity From the Perception-Meta-Perception Social Relations Model

2019 ◽  
Vol 50 (1) ◽  
pp. 24-37
Author(s):  
Ben Porter ◽  
Camilla S. Øverup ◽  
Julie A. Brunson ◽  
Paras D. Mehta
Keyword(s):  
Structural Equation Modeling ◽  
Social Relations ◽  
Latent Variables ◽  
Structural Equation ◽  
Multilevel Structural Equation Modeling ◽  
Equation Modeling ◽  
Complete Understanding ◽  
Social Relations Model ◽  
Flexible Framework ◽  
Multilevel Structural Equation

Abstract. Meta-accuracy and perceptions of reciprocity can be measured by covariances between latent variables in two social relations models examining perception and meta-perception. We propose a single unified model called the Perception-Meta-Perception Social Relations Model (PM-SRM). This model simultaneously estimates all possible parameters to provide a more complete understanding of the relationships between perception and meta-perception. We describe the components of the PM-SRM and present two pedagogical examples with code, openly available on https://osf.io/4ag5m . Using a new package in R (xxM), we estimated the model using multilevel structural equation modeling which provides an approachable and flexible framework for evaluating the PM-SRM. Further, we discuss possible expansions to the PM-SRM which can explore novel and exciting hypotheses.

Meïr Goldschmidt and the main currents in 19th-century Judaism

2001 ◽  
Vol 22 (1) ◽  
pp. 7-45 ◽  
Author(s):  
Kenneth Ober
Keyword(s):  
Nineteenth Century ◽  
19Th Century ◽  
Public Image ◽  
Complete Understanding ◽  
Literary Works ◽  
European Languages ◽  
Jewish Heritage ◽  
The Arts ◽  
Phenomenal Knowledge

Although the noted nineteenth-century Danish-Jewish writer Meïr Goldschmidt (1819–1887) made his entry into literature with a novel on Jewish themes, his later novels treated non-Jewish subjects, and his Jewish heritage appeared progressively to recede into the background of his public image. Literary historians have paid little attention to his complex perception of his own Jewishness and have made no effort to discover the immense significance he himself felt that Judaism had for his life and for his literary works. Moreover, no previous study has comprehensively treated Goldschmidt’s far-reaching network of interrelationships with an astonishing number of other major Jewish cultural figures of nineteenth-century Europe. During his restless travels crisscrossing Europe, which were facilitated by his phenomenal knowledge of the major European languages, he habitually sought out and associated with the leading Jewish figures in literature, the arts, journalism, and religion, but this fact and the resulting mutually influential connections he formed have been overlooked and ignored. This is the first focused and documented study of the Jewish aspect of Goldschmidt’s life, so vitally important to Goldschmidt himself and so indispensable to a complete understanding of his place in Danish and in world literatures.

Fin Level Defect Isolation Inside a FinFET Using Electron Beam Alteration of Current Flow

2017 ◽  
Author(s):  
H.J. Ryu ◽  
A.B. Shah ◽  
Y. Wang ◽  
W.-H. Chuang ◽  
T. Tong
Keyword(s):  
Electron Microscopy ◽  
Electron Beam ◽  
Focused Ion Beam ◽  
Current Flow ◽  
Ion Beam ◽  
The Body ◽  
Complete Understanding ◽  
Root Cause ◽  
Transmission Electron ◽  
Defect Isolation

Abstract When failure analysis is performed on a circuit composed of FinFETs, the degree of defect isolation, in some cases, requires isolation to the fin level inside the problematic FinFET for complete understanding of root cause. This work shows successful application of electron beam alteration of current flow combined with nanoprobing for precise isolation of a defect down to fin level. To understand the mechanism of the leakage, transmission electron microscopy (TEM) slice was made along the leaky drain contact (perpendicular to fin direction) by focused ion beam thinning and lift-out. TEM image shows contact and fin. Stacking fault was found in the body of the silicon fin highlighted by the technique described in this paper.

Interdisciplinary Client Care with the Neuman Systems Model

1998 ◽  
Vol 6 (3) ◽  
pp. 310-319
Author(s):  
Kevin M. Marett ◽  
Rae Jeanne Memmott ◽  
W. Eugene Gibbons ◽  
Randy L. Bott ◽  
Lee Duke
Keyword(s):  
Interdisciplinary Team ◽  
Common Language ◽  
Complete Understanding ◽  
Content Areas ◽  
Five Dimensions ◽  
Neuman Systems Model ◽  
Systems Model ◽  
Client Care ◽  
Neuman Systems ◽  
Client System

This article describes how the Neuman Systems Model (NSM) can be used in a two-step process to provide both the form and the function for interdisciplinary client care. The NSM proposes five dimensions of human experience as being necessary for a complete understanding of a client system. This article takes these five content areas—psychological, physiological, spiritual, developmental, and sociocultural—and extrapolates them to their respective disciplines (e.g. nursing, social work, religion, psychology, etc.) to create a comprehensive interdisciplinary model for client care. The NSM also provides a common language and conceptual paradigm, congruent with allied disciplines. A demonstration project incorporating the NSM in the formation and functioning of an interdisciplinary team is described.

Citizens, Elites, and Social Media Methodological Challenges and Opportunities in the Study of Persuasion and Mobilization

2019 ◽  
pp. 1036-1058
Author(s):  
Philip Habel ◽  
Yannis Theocharis
Keyword(s):  
Social Media ◽  
Big Data ◽  
Supply And Demand ◽  
Political Process ◽  
The Political ◽  
The Novel ◽  
Complete Understanding ◽  
Social Media Data ◽  
Challenges And Opportunities ◽  
Media Data

In the last decade, big data, and social media in particular, have seen increased popularity among citizens, organizations, politicians, and other elites—which in turn has created new and promising avenues for scholars studying long-standing questions of communication flows and influence. Studies of social media play a prominent role in our evolving understanding of the supply and demand sides of the political process, including the novel strategies adopted by elites to persuade and mobilize publics, as well as the ways in which citizens react, interact with elites and others, and utilize platforms to persuade audiences. While recognizing some challenges, this chapter speaks to the myriad of opportunities that social media data afford for evaluating questions of mobilization and persuasion, ultimately bringing us closer to a more complete understanding Lasswell’s (1948) famous maxim: “who, says what, in which channel, to whom, [and] with what effect.”

scholarly journals Food-Based Dietary Guidelines for Seafood Do Not Translate into Increased Long-Chain Omega-3 Levels in the Diet for U.S. Consumers

Foods ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 1816
Author(s):  
Michael F. Tlusty
Keyword(s):  
United States ◽  
Fatty Acids ◽  
National Level ◽  
The United States ◽  
Dietary Guidelines ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Complete Understanding ◽  
The U.S ◽  
Long Chain

Humans under-consume fish, especially species high in long-chain omega-3 fatty acids. Food-based dietary guidelines are one means for nations to encourage the consumption of healthy, nutritious food. Here, associations between dietary omega-3 consumption and food-based dietary guidelines, gross domestic product, the ranked price of fish, and the proportions of marine fish available at a national level were assessed. Minor associations were found between consumption and variables, except for food-based dietary guidelines, where calling out seafood in FBDGs did not associate with greater consumption. This relationship was explored for consumers in the United States, and it was observed that the predominant seafood they ate, shrimp, resulted in little benefit for dietary omega-3 consumption. Seafood is listed under the protein category in the U.S. Dietary Guidelines, and aggregating seafood under this category may limit a more complete understanding of its nutrient benefits beyond protein.

scholarly journals EnvIRONmental Aspects in Myelodysplastic Syndrome

2021 ◽  
Vol 22 (10) ◽  
pp. 5202
Author(s):  
Verena Petzer ◽  
Igor Theurl ◽  
Günter Weiss ◽  
Dominik Wolf
Keyword(s):  
Myelodysplastic Syndrome ◽  
Iron Overload ◽  
Iron Homeostasis ◽  
Clonal Evolution ◽  
Red Blood Cell Transfusion ◽  
Bone Marrow Niche ◽  
Environmental Aspects ◽  
Complete Understanding ◽  
Mediated Effects ◽  
Important Player

Systemic iron overload is multifactorial in patients suffering from myelodysplastic syndrome (MDS). Disease-immanent ineffective erythropoiesis together with chronic red blood cell transfusion represent the main underlying reasons. However, like the genetic heterogeneity of MDS, iron homeostasis is also diverse in different MDS subtypes and can no longer be generalized. While a certain amount of iron and reactive oxygen species (ROS) are indispensable for proper hematological output, both are harmful if present in excess. Consequently, iron overload has been increasingly recognized as an important player in MDS, which is worth paying attention to. This review focuses on iron- and ROS-mediated effects in the bone marrow niche, their implications for hematopoiesis and their yet unclear involvement in clonal evolution. Moreover, we provide recent insights into hepcidin regulation in MDS and its interaction between erythropoiesis and inflammation. Based on Tet methylcytosine dioxygenase 2 (TET2), representing one of the most frequently mutated genes in MDS, leading to disturbances in both iron homeostasis and hematopoiesis, we highlight that different genetic alteration may have different implications and that a comprehensive workup is needed for a complete understanding and development of future therapies.

scholarly journals Understanding the Relationship between Religiosity and Marital Commitment to Marital Stability: An Investigation on Indonesian Female Journalists

Religions ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 242
Author(s):  
Rena Latifa ◽  
Salsabila Salsabila ◽  
Heri Yulianto
Keyword(s):  
Marital Stability ◽  
P Value ◽  
Sampling Techniques ◽  
Complete Understanding ◽  
Marital Commitment ◽  
Female Journalists ◽  
Confirmatory Factor ◽  
Married Female ◽  
The Relationship ◽  
Variance Explained

The complete understanding of marital stability is hindered by limitations of theory and method, especially investigation on female journalists. The purpose of the current study was to test the effect of religiosity and marital commitment on the marital stability, by assessing Indonesian female journalists. This research used a quantitative approach with multiple regression analysis methods. The sample of this study involved 200 married female journalists residing in Jakarta and were taken using non-probability sampling techniques, specifically purposive sampling. The measurements used in this study were adaptations of the (1) Marital Stability Scale; (2) Centrality of Religiosity Scale (CRS-15); and (3) Inventory of Marital Commitments. Confirmatory factor analysis (CFA) was used to test the validity of each scale. The results of the F-test showed a p-value = 0.000 (significant), and a total variance explained (R2 value) of 0.224. This finding indicated that religiosity and marital commitment have a significant effect on marital stability (sig < 0.05). The direction of the coefficient regression of the religiosity variable and marital commitment is positive, indicating that the higher the religiosity and marital commitment, the higher the marital stability.

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