A new 1 : 1 cocrystal of lamotrigine and 1,2,3,6-hydrophthalimide: discovery, characterization, and construction of ternary phase diagrams

CrystEngComm ◽  
2020 ◽  
Vol 22 (15) ◽  
pp. 2681-2688
Author(s):  
Wenjie Kuang ◽  
Shaochang Ji ◽  
Yufeng Wei ◽  
Jinyan Zhang ◽  
Ping Lan
Keyword(s):  
Phase Diagram ◽  
Phase Diagrams ◽  
Ternary Phase ◽  
Ternary Phase Diagram ◽  
Ternary Phase Diagrams

A 1 : 1 cocrystal of lamotrigine (LAM) with 1,2,3,6-tetrahydrophthalimide (HPHT) was first successfully synthesized. The ternary phase diagram of the cocrystal was constructed, and its stability and dissolution were determined.

Calculation of phase diagrams and thermodynamic properties of 14 additive and reciprocal ternary systems containing Li2CO3, Na2CO3, K2CO3, Li2SO4, Na2SO4, K2SO4, LiOH, NaOH, and KOH

1984 ◽  
Vol 62 (3) ◽  
pp. 457-474 ◽  
Author(s):  
A. D. Pelton ◽  
C. W. Bale ◽  
P. L. Lin
Keyword(s):  
Phase Diagram ◽  
Thermodynamic Properties ◽  
Molten Salt ◽  
Phase Diagrams ◽  
Binary Systems ◽  
Ternary Phase ◽  
Ternary Phase Diagram ◽  
Ternary Systems ◽  
Maximum Error ◽  
Critical Assessment

Phase diagrams and thermodynamic properties of five additive molten salt ternary systems and nine reciprocal molten salt ternary systems containing the ions Li+, Na+, [Formula: see text], OH− are calculated from the thermodynamic properties of their binary subsystems which were obtained previously by a critical assessment of the thermodynamic data and the phase diagrams in these binary systems. Thermodynamic properties of ternary liquid phases are estimated from the binary properties by means of the Conformal Ionic Solution Theory. The ternary phase diagrams are then calculated from these thermodynamic properties by means of computer programs designed for the purpose. It is found that a ternary phase diagram can generally be calculated in this way with a maximum error about twice that of the maximum error in the binary phase diagrams upon which the calculations are based. If, in addition, some reliable ternary phase diagram measurements are available, these can be used to obtain small ternary correction terms. In this way, ternary phase diagram measurements can be smoothed and the isotherms drawn in a thermodynamically correct way. The thermodynamic approach permits experimental data to be critically assessed in the light of thermodynamic principles and accepted solution models. A critical assessment of error limits on all the calculated ternary diagrams is made, and suggestions as to which composition regions merit further experimental study are given.

scholarly journals Production, characterization and application of ternary phase diagrams for the purification of biodiesel produced from tropical almond seed oil

2021 ◽  
Vol 39 (4) ◽  
pp. 1066-1075
Author(s):  
K.K. Adama ◽  
U.P. Onochie ◽  
E. Gbeinzi
Keyword(s):  
Phase Diagrams ◽  
Ternary Phase ◽  
Seed Oil ◽  
Ternary Phase Diagram ◽  
Solubility Curve ◽  
Separation And Purification ◽  
Components Separation ◽  
Ternary Phase Diagrams ◽  
C 30 ◽  
Gas Chromatographic Method

This study presents the application of ternary phase diagrams to tropical almond biodiesel components separation and purification at two temperatures. The seed oil was extracted mechanically and alkaline transesterified to produce biodiesel. The oil and biodiesel were characterized using standard methods. Tie lines and binodal solubility curve data were determined using modified cloud point titration procedures. Gas chromatographic method was employed in the analysis of the phase compositions. The mixture of biodiesel, methanol and glycerol were investigated at 20 °C, 30 °C and withdrawal times of 2 to 32 minutes at 2 minutes intervals. Distribution coefficient, K and solvent selectivity, S analysis were performed. Results obtained showed that S > 1 indicating the ability of methanol to promote phase separation and purification. K < 1 implying that there was lower quantities of methanol solubilized in the biodiesel phase. The ternary phase diagrams provided the means of predicting the components distribution. Keywords: Production, Characterization, Tropical Almond Biodiesel, Purification, Ternary Phase Diagram

scholarly journals Liquid Regions of Lanthanum-Bearing Aluminosilicates

Materials ◽  
2020 ◽  
Vol 13 (2) ◽  
pp. 450
Author(s):  
Yandong Li ◽  
Tongsheng Zhang ◽  
Yefeng Feng ◽  
Chengjun Liu ◽  
Maofa Jiang
Keyword(s):  
Phase Diagram ◽  
Solid Oxide Fuel Cells ◽  
Phase Diagrams ◽  
Binary Systems ◽  
Ternary Phase ◽  
Ternary Phase Diagram ◽  
Energy Dispersive Spectrometer ◽  
Liquid Region ◽  
X Ray Diffraction ◽  
Calculated Liquid

The Al2O3-SiO2, La2O3-Al2O3, and La2O3-SiO2 binary phase diagrams were estimated by Redlich–Kister expression. La4.67Si3O13 (=La4.67(SiO4)3O) was introduced to improve the existing phase diagrams. The Al2O3-SiO2-La2O3 ternary phase diagram extrapolated by Kohler method was optimized. Then, the liquidus of Al2O3-SiO2-La2O3 system at 1600 °C was compared with Al2O3-SiO2-RE2O3 (RE = Rare Earth Elements) systems and experimental results in other literature. The high temperature experiments were conducted in the tube furnace at 1500 °C. Then the field emission scanning electron microscope (FE-SEM), energy dispersive spectrometer (EDS), and X-ray diffraction (XRD) were employed to verify the calculated liquid region and precipitates phase at 1500 °C. Moreover, the liquidus of binary systems were compared with FactSage results and experiments. The optimized ternary phase diagram shows the relatively reliable region of liquid phase, and it is significant to the seal glass of solid oxide fuel cells and other fields being related to RE containing silicates.

Liquidus Temperature Calculation in Sn-Bi-Cd System by ESTPHAD Method

2014 ◽  
Vol 790-791 ◽  
pp. 265-270
Author(s):  
Eszter Tatárka ◽  
Tamás Mende ◽  
András Roósz
Keyword(s):  
Phase Diagram ◽  
Phase Diagrams ◽  
Iteration Method ◽  
Liquidus Temperature ◽  
Binary Systems ◽  
Ternary Phase ◽  
Ternary Phase Diagram ◽  
Eutectic Point ◽  
Temperature Calculation ◽  
Binary Phase Diagrams

This paper includes the binary and ternary liquidus temperature calculations of Sn-Bi-Cd system. The calculation was performed in cases of the surfaces of Sn, Bi and Cd phases too. First of all the liquidus curves were calculated in the binary systems (Bi phase in Bi-Cd and Bi-Sn systems, Sn phase in Sn-Cd and Sn-Bi systems, Cd phase in Cd-Sn and Cd-Bi systems). By using the calculated coefficients of the binary phase diagrams and the data from the digitalized ternary phase diagram, the liquidus temperature of Sn, Bi and the Cd phases were calculated. Finally the eutectic point of the binary liquidus curves and the eutectic valley of the Sn and the Bi surfaces were calculated by means of an iteration method.

Using phase boundary mapping to resolve discrepancies in the Mg2Si–Mg2Sn miscibility gap

2021 ◽  
Author(s):  
Rachel Orenstein ◽  
James P. Male ◽  
Michael Toriyama ◽  
Shashwat Anand ◽  
G. Jeffrey Snyder
Keyword(s):  
Phase Diagram ◽  
Phase Boundary ◽  
Ternary Phase ◽  
Ternary Phase Diagram ◽  
Miscibility Gap ◽  
Boundary Mapping

A new understanding of the MgSi–MgSn miscibility gap is reached through phase boundary mapping the Mg–Si–Sn ternary phase diagram.

scholarly journals Part II. Model for the Protective Coating Formation During Hot Dip Galvanizing/ Część II. Model Formowania Powłoki Ochronnej Podczas Cynkowania Ogniowego

2014 ◽  
Vol 59 (4) ◽  
pp. 1393-1404 ◽  
Author(s):  
W. Wołczynski ◽  
Z. Pogoda ◽  
G. Garzeł ◽  
B. Kucharska ◽  
A. Sypien ◽  
...  
Keyword(s):  
Phase Diagram ◽  
Mass Balance ◽  
Protective Coating ◽  
Mathematical Description ◽  
Ternary Phase ◽  
Ternary Phase Diagram ◽  
Solute Redistribution ◽  
Zinc Bath ◽  
Flux System ◽  
Coating Formation

Abstract A mathematical description for the (Zn) - coating formation with the presence of flux in the zinc bath is presented. This description includes the progressive vanishing of the products of the flux disintegration. A function which expresses the flux vanishing is formulated. The solidification of some phase sub-layers in the (Zn) - coating is considered with the use of a hypothetical pseudo-ternary phase diagram Fe-Zn-flux. Some relationships are formulated to define the varying Zn - solute redistribution as observed across the sub-layers. The relationships are based on the mass balance analyzed for the coating / bath / flux system. An amount of the growing phase in a given sub-layers is also defined mathematically.

Formation of Salicylic Acid/4,4′-Dipyridyl Cocrystals Based on the Ternary Phase Diagram

2015 ◽  
Vol 38 (6) ◽  
pp. 1073-1080 ◽  
Author(s):  
Kyeong-Sill Lee ◽  
Kwang-Joo Kim ◽  
Joachim Ulrich
Keyword(s):  
Phase Diagram ◽  
Salicylic Acid ◽  
Ternary Phase ◽  
Ternary Phase Diagram

The use of acoustic spectroscopy in the characterisation of ternary phase diagrams

2013 ◽  
Vol 441 (1-2) ◽  
pp. 603-610 ◽  
Author(s):  
Giulia Bonacucina ◽  
Marco Cespi ◽  
Giovanna Mencarelli ◽  
Luca Casettari ◽  
Giovanni F. Palmieri
Keyword(s):  
Phase Diagrams ◽  
Ternary Phase ◽  
Ternary Phase Diagrams ◽  
Acoustic Spectroscopy
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