scholarly journals Electrophile dependent mechanisms in the asymmetric trapping of α-lithio-N-(tert-butoxythiocarbonyl)azetidine

2020 ◽  
Vol 56 (81) ◽  
pp. 12174-12177
Author(s):  
Pascal K. Delany ◽  
Claire L. Mortimer ◽  
David M. Hodgson
Keyword(s):  
Low Temperature ◽  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

α-Lithio-N-Botc azetidine, configurationally unstable at low temperature, reacts with fast-trapping electrophiles by dynamic thermodynamic resolution, but with slow-trapping electrophiles by dynamic kinetic resolution.

Development of a Robust and Highly Selective Ru(II)-Catalyzed Dynamic Kinetic Resolution Used to Manufacture AMG 232

2020 ◽  
Vol 24 (6) ◽  
pp. 1164-1174
Author(s):  
Austin G. Smith ◽  
Matthew M. Bio ◽  
John T. Colyer ◽  
Khalid Diker ◽  
Gilles Gorins ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

Catalytic Atroposelective Dynamic Kinetic Resolution of Biaryl Lactones with Activated Isocyanides

2021 ◽  
Author(s):  
Linghui Qian ◽  
Ling-Fei Tao ◽  
Wen-Tao Wang ◽  
Ehtesham Jameel ◽  
Zhang-Hong Luo ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

Efforts towards a Noyori reduction of a 3-fluorpiperidin-4-one with dynamic kinetic resolution

2021 ◽  
pp. 152764
Author(s):  
Jacques Le Paih ◽  
Dane A. Goff ◽  
Rajinder Singh ◽  
Simon J. Shaw
Keyword(s):  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution
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