Metal–organic complex-based chemodynamic therapy agents for cancer therapy

2020 ◽  
Vol 56 (60) ◽  
pp. 8332-8341
Author(s):  
Eunbin Hwang ◽  
Hyo Sung Jung

This feature article summarizes the recent progress in the study of chemodynamic therapy agents based on metal–organic complexes.

2018 ◽  
Vol 6 (3) ◽  
pp. 805-810 ◽  
Author(s):  
Dafeng Yan ◽  
Chung-Li Dong ◽  
Yu-Cheng Huang ◽  
Yuqin Zou ◽  
Chao Xie ◽  
...  

For the first time, we have successfully generated coordinatively unsaturated metal sites in phytic acid–Co2+ based metal–organic complexes by engineering the coordination geometry with room-temperature plasma technology.


CrystEngComm ◽  
2021 ◽  
Author(s):  
Yanru Wang ◽  
A-Ni Wang ◽  
Jie Pan ◽  
Zhenzhen Xue ◽  
Jinhua Li ◽  
...  

Metal–organic complexes (MOCs) derived porous carbon have attracted a great deal of attention in terms of easy functionalization with metal/metal oxides or other heteroatoms and hierarchical porosity. Herein, four g-C3N4/TiO2/CNOT...


2020 ◽  
Vol 8 (32) ◽  
pp. 7189-7196 ◽  
Author(s):  
Zelei Jiang ◽  
Tong Wang ◽  
Shuai Yuan ◽  
Mengfan Wang ◽  
Wei Qi ◽  
...  

Tumor-sensitive bioMOC-Zn(Cys) was developed using an endogenous Zn2+ ion and l-cystine for the delivery of anti-cancer drug DOX. In vivo application of DOX@bioMOC-Zn(Cys) shows the increased inhibition of tumor growth and prevented side effects.


1997 ◽  
Vol 77 (4) ◽  
pp. 613-619 ◽  
Author(s):  
G. S. R. Krishnamurti ◽  
P. M. Huang ◽  
L. M. Kozak ◽  
H. P. W. Rostad ◽  
K. C. J. Van Rees

The distribution of Cd with depth, its particulate-bound speciation and availability index were studied in nine typical soil profiles of Saskatchewan, Canada. In the Ap horizons, Cd was predominantly in the metal-organic complex-bound form, accounting for about 38.8%, on average, of the total Cd present in the soils. The carbonate-bound Cd and the metal-organic complex-bound Cd accounted for 33.5 and 12.9%, respectively, on average, of the total Cd present in the B horizons. In the Ck horizons, Cd was predominantly in the carbonate-bound form, accounting for about 70.9%, on average, of the total Cd present in the soils. The M NH4Cl-extractable Cd of the soils, which is a measure of availability index of soil Cd, generally decreased with depth. Statistical treatment of the M NH4Cl-extractable Cd with different particulate-bound Cd species of various horizons in the soil profiles showed its highest correlation (P = 2.0 × 10−9, n = 42) with the amount of the metal-organic complex-bound Cd species, indicating the importance of the metal-organic complex-bound Cd species in Cd availability to the plants. Key words: Cadmium, soil profile, speciation, availability index, metal-organic complexes


2021 ◽  
Author(s):  
Yurong Liu ◽  
Wenzheng Lu ◽  
Xizhe Cheng ◽  
Jianfang Wang ◽  
Wai-Yeung Raymond Wong

2D metal-organic complex nanosheets with the merits of high stability and structure tunability are an emerging topic in recent years. To extend the promising ultrathin architectures, a new Co(II) complex...


2017 ◽  
Vol 64 (11) ◽  
pp. 4628-4635 ◽  
Author(s):  
Anu ◽  
Archana Sharma ◽  
Md. Shahzad Khan ◽  
Anurag Srivastava ◽  
Mushahid Husain ◽  
...  

2021 ◽  
Author(s):  
zohreh razmara ◽  
Fereshteh Shiri ◽  
Pouya Karimi ◽  
Marek Necas

Abstract A novel metal-organic complex formulated as [Cd (phen)(dipic) (H2O)2]. 3 H2O (phen = 1, 10-phenanthroline; dipic2−= pyridine-2,6-dicarboxylate) has been hydrothermally synthesized at 150°C for 48h. The structure of Cd complex was characterized by elemental analysis, Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), differential thermal analysis (DTA), and single-crystal X-ray diffraction (SC-XRD). The crystal system of Cd complex is monoclinic with space group C 2/c. The pentagonal bipyramid (seven coordinate) around Cd2+ center filled by two terminal water ligands, one 1,10-phenanthroline, and one pyridine-2,6-dicarboxylate anion. Extensive O–H···O hydrogen bonding interactions involving all coordinated water molecules, dipicolinate oxygens, and crystallization water molecules further stabilize the complex units by linking them to form three-dimensional polymeric networks. Indeed, quantum mechanical studies were performed to understand effective factors on stability of the Cd(II) complex.


2018 ◽  
Vol 42 (11) ◽  
pp. 575-578 ◽  
Author(s):  
Di Cheng ◽  
Ya-Ping Zhang ◽  
Ke Wang ◽  
Xiang-Ru Meng ◽  
Xiao-Fei Li

The metal–organic complex {[Zn(immb)(suc)]·H2O}n [immb = 2-[(1H-imidazol-1-yl)methyl]-6-methyl-1H-benzimidazole, H2suc = succinic acid] has been prepared and its crystal structure determined. Its fluorescence and thermogravimetric data have also been obtained.


2020 ◽  
Vol 107 ◽  
pp. 110068
Author(s):  
K.B Manjunatha ◽  
Dileep Ramakrishna ◽  
B.J. Rudresha ◽  
Albin Antony ◽  
P. Poornesh

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