Organocatalytic enantioselective allylic alkylation of α-aryl γ-lactones: an approach to densely functionalized quaternary stereocentres

2020 ◽  
Vol 56 (49) ◽  
pp. 6640-6643
Author(s):  
Morgane Mando ◽  
Fabienne Grellepois ◽  
Emmanuel Riguet
Keyword(s):  
Lewis Base ◽  
Allylic Alkylation ◽  
Asymmetric Allylic Alkylation

The asymmetric allylic alkylation of α-aryl γ-lactones involving the activation of Morita–Baylis–Hillman carbonates by an original chiral Lewis base is reported.

Copper/Lewis base cooperatively catalyzed asymmetric allylic alkylation of Morita−Baylis−Hillman carbonates with azomethine ylides

2021 ◽  
Author(s):  
Yimin Hu ◽  
Zhengyang Yan ◽  
Wangyu Shi ◽  
Jianning Liao ◽  
Min Liu ◽  
...  
Keyword(s):  
Lewis Base ◽  
Azomethine Ylides ◽  
Allylic Alkylation ◽  
Asymmetric Allylic Alkylation ◽  
Cooperative Catalysis

In this paper, an asymmetric allylic alkylation of easily available azomethine ylides with Morita−Baylis−Hillman (MBH) Carbonates through a copper (I) / Lewis base cooperative catalysis strategy has been realized. The...

ChemInform Abstract: Lewis Base Assisted Broensted Base Catalysis: Direct Asymmetric Allylic Alkylation of Indenes.

ChemInform ◽  
2012 ◽  
Vol 43 (19) ◽  
pp. no-no
Author(s):  
Hai-Lei Chui ◽  
Xun-Hao Sun ◽  
Lin Jiang ◽  
Lin Dong ◽  
Yin-Chun Chen
Keyword(s):  
Lewis Base ◽  
Base Catalysis ◽  
Allylic Alkylation ◽  
Asymmetric Allylic Alkylation

Lewis Base Assisted Brønsted Base Catalysis: Direct Asymmetric Allylic Alkylation of Indenes

2011 ◽  
Vol 2011 (36) ◽  
pp. 7366-7371 ◽  
Author(s):  
Hai-Lei Cui ◽  
Xun-Hao Sun ◽  
Lin Jiang ◽  
Lin Dong ◽  
Ying-Chun Chen
Keyword(s):  
Lewis Base ◽  
Base Catalysis ◽  
Allylic Alkylation ◽  
Asymmetric Allylic Alkylation ◽  
Brønsted Base

Novel Chiral Ligands for Palladium-catalyzed Asymmetric Allylic Alkylation/ Asymmetric Tsuji-Trost Reaction: A Review

2019 ◽  
Vol 23 (11) ◽  
pp. 1168-1213 ◽  
Author(s):  
Samar Noreen ◽  
Ameer Fawad Zahoor ◽  
Sajjad Ahmad ◽  
Irum Shahzadi ◽  
Ali Irfan ◽  
...  
Keyword(s):  
Asymmetric Catalysis ◽  
Enantioselective Synthesis ◽  
Chiral Ligands ◽  
Allylic Alkylation ◽  
Research Groups ◽  
Asymmetric Allylic Alkylation ◽  
Catalytic Potential ◽  
Long Time ◽  
Palladium Catalyzed ◽  
Alkylation Reactions

Background: Asymmetric catalysis holds a prestigious role in organic syntheses since a long time and chiral inductors such as ligands have been used to achieve the utmost desired results at this pitch. The asymmetric version of Tsuji-Trost allylation has played a crucial role in enantioselective synthesis. Various chiral ligands have been known for Pdcatalyzed Asymmetric Allylic Alkylation (AAA) reactions and exhibited excellent catalytic potential. The use of chiral ligands as asymmetric inductors has widened the scope of Tsuji-Trost allylic alkylation reactions. Conclusion: Therefore, in this review article, a variety of chiral inductors or ligands have been focused for palladium catalyzed asymmetric allylic alkylation (Tsuji-Trost allylation) and in this regard, recently reported literature (2013-2017) has been described. The use of ligands causes the induction of enantiodiscrimination to the allylated products, therefore, the syntheses of various kinds of ligands have been targeted by many research groups to employ in Pd-catalyzed AAA reactions.

Cytisine as a scaffold for ortho-diphenylphosphinobenzenecarboxamide ligands for Pd-catalyzed asymmetric allylic alkylation

2015 ◽  
Vol 778 ◽  
pp. 10-20 ◽  
Author(s):  
Irena Philipova ◽  
Georgi Stavrakov ◽  
Nikolay Vassilev ◽  
Rositsa Nikolova ◽  
Boris Shivachev ◽  
...  
Keyword(s):  
Allylic Alkylation ◽  
Asymmetric Allylic Alkylation
Sign in / Sign up

Export Citation Format

Share Document