A H2O2-free electrochemical peptide biosensor based on Au@Pt bimetallic nanorods for highly sensitive sensing of matrix metalloproteinase 2

2020 ◽  
Vol 56 (45) ◽  
pp. 6039-6042 ◽  
Author(s):  
Xiaoxue Xi ◽  
Meiqi Wen ◽  
Shihao Song ◽  
Junlun Zhu ◽  
Wei Wen ◽  
...  

We construct for the first time a H2O2-free electrochemical peptide biosensor based on Au@Pt bimetallic nanorods in neutral substrate solutions for highly sensitive detection of matrix metalloproteinase 2.

2016 ◽  
Vol 52 (57) ◽  
pp. 8838-8841 ◽  
Author(s):  
Yong Liu ◽  
Fangfang Meng ◽  
Longwei He ◽  
Xiaoqiang Yu ◽  
Weiying Lin

In this work, we developed a unique fluorescent probe HVC-6 for highly sensitive detection of RNA in pure water systems and living systems by aggregation–disaggregation of the probe for the first time.


Author(s):  
Hee Jun Shin ◽  
Hae Won Jang ◽  
Gyeongsik Ok

We demonstrate, for the first time, a highly sensitive detection of 4-methylimidazole (4-MeI), a carcinogenic material, by applying an electric field enhancement technique using a terahertz (THz) metamaterial at the THz region. The THz metamaterials were fabricated with a metal array using an electric-field-coupled inductor-capacitor (ELC) resonator structure, and FDTD simulation showed good agreement with experimental results. We measured the THz spectra of the metamaterials to detect 4-MeI concentrations of 0, 1, 2, 5, 10, 15, and 20 mg/L. The resonance frequency of the metamaterial was shifted by approximately 8 GHz and transmittance at the resonance frequency increased to 2 x 10-3 as the concentration was increased, up to 20 mg/L. Our study provides new insight into application of metamaterials to detect carcinogen using a THz technique.


Author(s):  
Xiaojia Jiang ◽  
Mingsong Zang ◽  
Fei Li ◽  
Chunxi Hou ◽  
Quan Luo ◽  
...  

Biological nanopore-based techniques have attracted more and more attention recently in the field of single-molecule detection, because they allow the real-time, sensitive, high-throughput analysis. Herein, we report an engineered biological...


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