A three-dimensional BODIPY–iron(iii) compound with improved H2O2-response for NIR-II photoacoustic imaging guided chemodynamic/photothermal therapy

2020 ◽  
Vol 56 (46) ◽  
pp. 6281-6284 ◽  
Author(s):  
Changjin Ou ◽  
Yewei Zhang ◽  
Wei Ge ◽  
Liping Zhong ◽  
Yong Huang ◽  
...  

3D boron dipyrromethene (BODIPY)–Fe(iii) coordination polymer nanoparticles with NIR-II absorption were developed as photothermal and chemodynamic agent to effectively kill cancer cells.

2019 ◽  
Vol 12 (03) ◽  
pp. 1930001 ◽  
Author(s):  
Xiaoju Men ◽  
Zhen Yuan

Photoacoustic imaging (PAI) is a hybrid imaging method based on photoacoustic (PA) effects, which is able to capture the structure, function, and molecular information of biological tissues with high resolution. To date, therapeutic techniques under the guidance of PAI have provided new strategies for accurate diagnosis and precise treatment of tumors. In particular, conjugated polymer nanoparticles have been extensively inspected for PA-based cancer theranostics largely due to their superior optical properties such as tunable spectrum and large absorption coefficient and their good biocompatibility, and abundant functional groups. This mini-review mainly focuses on the recent advances toward the development of novel conjugated polymer nanoparticles for PA-based multimodal imaging and cancer photothermal therapy.


2017 ◽  
Vol 5 (9) ◽  
pp. 1772-1778 ◽  
Author(s):  
Xiangjun Chen ◽  
Manjie Zhang ◽  
Shengnan Li ◽  
Lu Li ◽  
Lingyu Zhang ◽  
...  

A facile route was developed to fabricate PPy@MOF for dual-mode magnetic resonance/photoacoustic imaging and synergistic chemo-photothermal therapy.


2017 ◽  
Vol 1 (8) ◽  
pp. 1556-1562 ◽  
Author(s):  
Xiaolei Cai ◽  
Jie Liu ◽  
Weng Heng Liew ◽  
Yukun Duan ◽  
Junlong Geng ◽  
...  

We report organic nanoparticles for efficient photoacoustic imaging and photothermal therapy, based on the small molecule BTPETTQ which has a propeller structure and a donor–acceptor–donor configuration.


2019 ◽  
Vol 7 (24) ◽  
pp. 3856-3864 ◽  
Author(s):  
Mengxue Liu ◽  
Jiulong Zhang ◽  
Xin Li ◽  
Chao Cai ◽  
Xueyan Cao ◽  
...  

A novel targeted theranostic nanoplatform (LAP–Fe3O4@PDA–PEG–PBA) is constructed for magnetic resonance and photoacoustic imaging-guided photothermal therapy of cancer cells overexpressing sialic acid.


Nanoscale ◽  
2019 ◽  
Vol 11 (31) ◽  
pp. 14727-14733 ◽  
Author(s):  
Biqing Bao ◽  
Li Tong ◽  
Yu Xu ◽  
Jingjing Zhang ◽  
Xue Zhai ◽  
...  

Semiconducting polymer nanoparticles encapsulated with polydopamine as both the protection and bioconjugation layer for amplified photoacoustic imaging and photothermal therapy are proposed.


2021 ◽  
Vol 9 (14) ◽  
pp. 3153-3160
Author(s):  
Xin Jin ◽  
Xiaoyi Xing ◽  
Qingyuan Deng ◽  
Weixia Qing ◽  
Zhonghua Liu ◽  
...  

This work presents an efficient method of accessing DPP-SO that not only possess an excellent anti-tumour property but also regulates the photothermal performance of DPP-conjugated polymers by changing the heteroatom in the molecular skeleton.


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