Dehydroamino acid chemical biology: an example of functional group interconversion on proteins

Lyn H. Jones

doi:10.1039/d0cb00174k

Dehydroamino acid chemical biology: an example of functional group interconversion on proteins

RSC Chemical Biology ◽

10.1039/d0cb00174k ◽

2020 ◽

Vol 1 (5) ◽

pp. 298-304

Author(s):

Lyn H. Jones

Keyword(s):

Chemical Biology ◽

Functional Group ◽

New Concepts ◽

Dehydroamino Acid

The chemical biology of dehydroalanine and dehydrobutyrine in proteins is summarized and new concepts are presented.

Download Full-text

Cluster Preface: Metathesis Reactions beyond Olefins

Synlett ◽

10.1055/s-0039-1690296 ◽

2019 ◽

Vol 30 (17) ◽

pp. 1952-1953

Author(s):

Bill Morandi

Keyword(s):

Organic Chemistry ◽

Research Program ◽

Research Group ◽

Chemical Biology ◽

Materials Science ◽

Building Blocks ◽

Associate Professor ◽

Independent Research ◽

Max Planck ◽

New Concepts

studied at the ETH Zurich from 2003–2012, earning a B.Sc. in biology, an M.Sc. in chemical biology and a Ph.D. in organic chemistry working with Prof. Erick M. Carreira. After a postdoc with Prof. Robert H. Grubbs at CalTech, he led an independent Max Planck Research Group from 2014–2018 at the Max-Planck-Institut für Kohlenforschung, Germany. Since July 2018, he is a tenured Associate Professor at the ETH Zurich where he holds a chair in synthetic organic chemistry. His independent research program targets the development of new concepts in catalysis, with a particular emphasis on employing inexpensive and sustainable catalysts to transform broadly available feedstocks, such as polyols and hydrocarbons, into valuable building blocks for applications in medicine and materials science.

Download Full-text

Novel Approaches to Low-Voltage Scanning Electron Microscopy

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100180586 ◽

1990 ◽

Vol 48 (1) ◽

pp. 366-367

Author(s):

Arthur V. Jones

Keyword(s):

Electron Microscopy ◽

Scanning Electron Microscopy ◽

Low Voltage ◽

Electron Optics ◽

Current Interest ◽

New Concepts ◽

Opportune Time ◽

Novel Approaches ◽

Voltage Scanning ◽

Scanning Electron

In comparison with the developers of other forms of instrumentation, scanning electron microscope manufacturers are among the most conservative of people. New concepts usually must wait many years before being exploited commercially. The field emission gun, developed by Albert Crewe and his coworkers in 1968 is only now becoming widely available in commercial instruments, while the innovative lens designs of Mulvey are still waiting to be commercially exploited. The associated electronics is still in general based on operating procedures which have changed little since the original microscopes of Oatley and his co-workers.The current interest in low-voltage scanning electron microscopy will, if sub-nanometer resolution is to be obtained in a useable instrument, lead to fundamental changes in the design of the electron optics. Perhaps this is an opportune time to consider other fundamental changes in scanning electron microscopy instrumentation.

Download Full-text