scholarly journals 2021 Biomaterials Science Emerging Investigators Issue In-silico design of additively manufacturable composite synthetic vascular conduits and grafts with tuneable compliance

2021 ◽  
Author(s):  
Oisín Sean Byrne ◽  
Fergal Brian Coulter ◽  
Ellen T Roche ◽  
Eoin D O'Cearbhaill
Keyword(s):  
Medical Devices ◽  
Clinical Assessment ◽  
In Silico ◽  
Critical Part ◽  
In Silico Design ◽  
Physiological Conditions

Benchtop testing of endovascular medical devices under accurately simulated physiological conditions is a critical part of device evaluation prior to clinical assessment. Currently, glass, acrylic and silicone vascular models are...

Developing FGFR4 Inhibitors As Potential Anti-Cancer Agents Via In Silico Design, Supported by In Vitro and Cell-Based Testing

2013 ◽  
Vol 999 (999) ◽  
pp. 1-15
Author(s):  
H.K. Ho ◽  
G. Nemeth ◽  
Y.R. Ng ◽  
E. Pang ◽  
C. Szantai-Kis ◽  
...  
Keyword(s):  
In Silico ◽  
In Silico Design ◽  
Anti Cancer

In silico design of epitope-based peptide vaccine against non-typhoidal Salmonella through immunoinformatic approaches

2021 ◽  
pp. 1-19
Author(s):  
Md. Chayan Ali ◽  
Mst. Shanzeda Khatun ◽  
Sultana Israt Jahan ◽  
Raju Das ◽  
Yeasmin Akter Munni ◽  
...  
Keyword(s):  
In Silico ◽  
Peptide Vaccine ◽  
In Silico Design

scholarly journals In silico design and in vitro expression of novel multiepitope DNA constructs based on HIV-1 proteins and Hsp70 T-cell epitopes

2021 ◽  
Author(s):  
Elahe Akbari ◽  
Kimia Kardani ◽  
Ali Namvar ◽  
Soheila Ajdary ◽  
Esmat Mirabzadeh Ardakani ◽  
...  
Keyword(s):  
T Cell ◽  
In Silico ◽  
T Cell Epitopes ◽  
In Vitro Expression ◽  
In Silico Design ◽  
Hiv 1

scholarly journals In silico imaging clinical trials: cheaper, faster, better, safer, and more scalable

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Aldo Badano
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Medical Devices ◽  
In Silico ◽  
Lessons Learned ◽  
Patient Access ◽  
High Quality ◽  
Virtual Imaging ◽  
Regulatory Evaluation

AbstractImaging clinical trials can be burdensome and often delay patient access to novel, high-quality medical devices. Tools for in silico imaging trials have significantly improved in sophistication and availability. Here, I describe some of the principal advantages of in silico imaging trials and enumerate five lessons learned during the design and execution of the first all-in silico virtual imaging clinical trial for regulatory evaluation (the VICTRE study).

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