Strontium-substituted hydroxyapatite grown on graphene oxide nanosheet-reinforced chitosan scaffold to promote bone regeneration

2020 ◽  
Vol 8 (16) ◽  
pp. 4603-4615 ◽  
Author(s):  
Tingting Wu ◽  
Binglin Li ◽  
Wanshun Wang ◽  
Lingling Chen ◽  
Zhan Li ◽  
...  

SrHA grown on GO nanosheet-reinforced chitosan scaffolds promoted the bone regeneration as SrHA and GO had good osteoconductivity and high ALP activity while the chitosan matrix played a role in antibacteria.

2018 ◽  
Vol 6 (3) ◽  
pp. 538-549 ◽  
Author(s):  
Lu Han ◽  
Honglong Sun ◽  
Pengfei Tang ◽  
Pengfei Li ◽  
Chaoming Xie ◽  
...  

A mussel-inspired modification method was employed for depositing GO on inert Ti scaffolds to obtain GO/Ti hybrid scaffolds.


2020 ◽  
Vol 21 (15) ◽  
pp. 5202 ◽  
Author(s):  
Sonia How Ming Wong ◽  
Siew Shee Lim ◽  
Timm Joyce Tiong ◽  
Pau Loke Show ◽  
Hayyiratul Fatimah Mohd Zaid ◽  
...  

An ideal scaffold should be biocompatible, having appropriate microstructure, excellent mechanical strength yet degrades. Chitosan exhibits most of these exceptional properties, but it is always associated with sub-optimal cytocompatibility. This study aimed to incorporate graphene oxide at wt % of 0, 2, 4, and 6 into chitosan matrix via direct blending of chitosan solution and graphene oxide, freezing, and freeze drying. Cell fixation, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide, alkaline phosphatase colorimetric assays were conducted to assess cell adhesion, proliferation, and early differentiation of MG63 on chitosan–graphene oxide scaffolds respectively. The presence of alkaline phosphatase, an early osteoblast differentiation marker, was further detected in chitosan–graphene oxide scaffolds using western blot. These results strongly supported that chitosan scaffolds loaded with graphene oxide at 2 wt % mediated cell adhesion, proliferation, and early differentiation due to the presence of oxygen-containing functional groups of graphene oxide. Therefore, chitosan scaffolds loaded with graphene oxide at 2 wt % showed the potential to be developed into functional bone scaffolds.


2012 ◽  
Vol 409-410 ◽  
pp. 156-163 ◽  
Author(s):  
Hua-Dong Huang ◽  
Peng-Gang Ren ◽  
Jun Chen ◽  
Wei-Qin Zhang ◽  
Xu Ji ◽  
...  

2016 ◽  
Vol 16 (12) ◽  
pp. 12426-12432 ◽  
Author(s):  
Linyan Yu ◽  
Xiongwei Wu ◽  
Qi Liu ◽  
Liangliang Liu ◽  
Xinyu Jiang ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (27) ◽  
pp. 22320-22330 ◽  
Author(s):  
Nazia Kausar ◽  
Indranil Roy ◽  
Dipankar Chattopadhyay ◽  
Asish R. Das

Graphene oxide nanosheet catalyzed strategies for construction of 2,3-dihydroquinazolinones and quinazolin-4(3H)-ones starting from anthranilamide and an aldehyde/ketone in aqueous medium at room temperature have been realized.


2017 ◽  
Vol 3 (4) ◽  
pp. 619-627 ◽  
Author(s):  
Valentina Palmieri ◽  
Francesca Bugli ◽  
Maria Carmela Lauriola ◽  
Margherita Cacaci ◽  
Riccardo Torelli ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (59) ◽  
pp. 54525-54538 ◽  
Author(s):  
K. Naveen Kumar ◽  
R. Padma ◽  
J. L. Rao ◽  
Misook Kang

Novel dazzling green emission has been obtained from graphene oxide nanosheet-embedded Ce3+ and Tb3+:PVA polymer nanocomposites under UV excitation. The green emission of Tb3+ is enhanced by an energy transfer from Ce3+ to Tb3+ and GO NS to Tb3+.


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