Advances in living cell-based anticancer therapeutics

2020 ◽  
Vol 8 (9) ◽  
pp. 2344-2365 ◽  
Author(s):  
He Dong ◽  
Xiao Xu ◽  
Leikun Wang ◽  
Ran Mo
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Anticancer Drug ◽  
Living Cell ◽  
Drug Carriers ◽  
Living Cells ◽  
Anticancer Drug Delivery ◽  
Recent Advances ◽  
Anticancer Therapeutics

This review summarizes recent advances in the applications of living cells as drug carriers or active drugs for anticancer drug delivery and cancer therapy.

Advances in Nanoparticles as Anticancer Drug Delivery Vector: Need of this Century

2020 ◽  
Vol 26 (15) ◽  
pp. 1637-1649 ◽  
Author(s):  
Imran Ali ◽  
Sofi D. Mukhtar ◽  
Heyam S. Ali ◽  
Marcus T. Scotti ◽  
Luciana Scotti
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Medical Science ◽  
Drug Carriers ◽  
Anticancer Drug Delivery ◽  
Ph Values ◽  
Delivery Vector ◽  
Future Challenges ◽  
Smart Drug ◽  
Smart Drug Delivery

Background: Nanotechnology has contributed a great deal to the field of medical science. Smart drugdelivery vectors, combined with stimuli-based characteristics, are becoming increasingly important. The use of external and internal stimulating factors can have enormous benefits and increase the targeting efficiency of nanotechnology platforms. The pH values of tumor vascular tissues are acidic in nature, allowing the improved targeting of anticancer drug payloads using drug-delivery vectors. Nanopolymers are smart drug-delivery vectors that have recently been developed and recommended for use by scientists because of their potential targeting capabilities, non-toxicity and biocompatibility, and make them ideal nanocarriers for personalized drug delivery. Method: The present review article provides an overview of current advances in the use of nanoparticles (NPs) as anticancer drug-delivery vectors. Results: This article reviews the molecular basis for the use of NPs in medicine, including personalized medicine, personalized therapy, emerging vistas in anticancer therapy, nanopolymer targeting, passive and active targeting transports, pH-responsive drug carriers, biological barriers, computer-aided drug design, future challenges and perspectives, biodegradability and safety. Conclusions: This article will benefit academia, researchers, clinicians, and government authorities by providing a basis for further research advancements.

Micro/nanomachines: what is needed for them to become a real force in cancer therapy?

Nanoscale ◽  
2019 ◽  
Vol 11 (14) ◽  
pp. 6519-6532 ◽  
Author(s):  
Lucie Reinišová ◽  
Soňa Hermanová ◽  
Martin Pumera
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Anticancer Drug ◽  
Future Development ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Anticancer Drug Delivery

A biomedical perspective is used to assess micro/nanomotor-based anticancer drug delivery systems with recommendations for their effective future development.

Nanoparticles and mesenchymal stem cells: a win-win alliance for anticancer drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (43) ◽  
pp. 36910-36922 ◽  
Author(s):  
Min Li ◽  
Fangrong Zhang ◽  
Kerong Chen ◽  
Cheng Wang ◽  
Yujie Su ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cancer Therapy ◽  
Anticancer Drug ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Anticancer Drug Delivery

Schematic illustration of the combination of NPs and MSCs drug delivery systems for cancer therapy.

Multifunctional sharp pH-responsive nanoparticles for targeted drug delivery and effective breast cancer therapy

2019 ◽  
Vol 7 (4) ◽  
pp. 576-585 ◽  
Author(s):  
Yandan Yao ◽  
Phei Er Saw ◽  
Yan Nie ◽  
Ping-Pui Wong ◽  
Linjia Jiang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cancer Therapy ◽  
Anticancer Drug ◽  
Targeted Drug Delivery ◽  
Ph Responsive ◽  
Breast Cancer Therapy ◽  
Anticancer Drug Delivery ◽  
Targeted Drug

A new multifunctional pH-responsive NP platform was developed for targeted anticancer drug delivery and effective breast cancer therapy.

scholarly journals Pluronic F127 self-assembled MoS2 nanocomposites as an effective glutathione responsive anticancer drug delivery system

RSC Advances ◽  
2019 ◽  
Vol 9 (44) ◽  
pp. 25592-25601 ◽  
Author(s):  
Adhisankar Vadivelmurugan ◽  
Rajeshkumar Anbazhagan ◽  
Vinothini Arunagiri ◽  
Juin-Yih Lai ◽  
Hsieh-Chih Tsai
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Drug Carrier ◽  
Pluronic F127 ◽  
Anticancer Drug Delivery ◽  
System P ◽  
Self Assembled

In this study, bio-responsive polymeric MoS2 nanocomposites were prepared for use as a drug carrier for cancer therapy.

scholarly journals Surface charge switchable and core cross-linked polyurethane micelles as a reduction-triggered drug delivery system for cancer therapy

RSC Advances ◽  
2017 ◽  
Vol 7 (18) ◽  
pp. 11021-11029 ◽  
Author(s):  
Chang Liu ◽  
Yayuan Guan ◽  
Yuling Su ◽  
Lili Zhao ◽  
Fancui Meng ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Surface Charge ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Drug Carriers ◽  
Ph Responsive ◽  
The Core

The core cross-linked polyurethane micelles with redox sensitive and pH-responsive surface charge switchable properties were prepared by using diisocyanates as crosslinkers and studied as anticancer drug carriers.

Recent Advances in Mesoporous Silica and Gold Based Nanovectors in Anticancer Drug Delivery System

2017 ◽  
Vol 21 (23) ◽  
Author(s):  
Imran Ali ◽  
Sofi Danish Mukhtar ◽  
Mohammad Nadeem Lone ◽  
Heyam Saad Ali ◽  
Hassan Y. Aboul-Enein
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Anticancer Drug Delivery ◽  
Recent Advances

scholarly journals Supramolecular anticancer drug delivery systems based on linear–dendritic copolymers

2015 ◽  
Vol 6 (14) ◽  
pp. 2580-2615 ◽  
Author(s):  
Homa Gheybi ◽  
Mohsen Adeli
Keyword(s):  
Drug Delivery ◽  
Hybrid Systems ◽  
Anticancer Drug ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Anticancer Drug Delivery ◽  
Recent Advances ◽  
Two Generations

The combination of two generations of polymers as linear–dendritic copolymers leads to hybrid systems with unique properties, which are of great interest for many applications. Herein, recent advances in anticancer drug delivery systems based on linear–dendritic copolymers have been reviewed.

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