Probing the methotrexate–protein interactions by proteomics and thermostability assay for drug resistance study

2021 ◽  
Author(s):  
Wenbo Zhang ◽  
Xiaoying Li ◽  
Xiaolei Zhang ◽  
Yan Dong ◽  
Lianghai Hu
Keyword(s):  
Drug Resistance ◽  
Protein Interactions ◽  
Quantitative Proteomics ◽  
Drug Action ◽  
Novel Strategy

Quantitative proteomics combined with thermostability assay provide a novel strategy for the study of mechanisms on drug action and resistance.

Cisplatin Resistance Reversal of Lung Cancers by Tumor Acidity-Activable Vesicular Nanoreactors via Tumor Oxidative Stress Amplification

2021 ◽  
Author(s):  
Jean Felix Mukerabigwi ◽  
Yu Han ◽  
Nannan Lu ◽  
Wendong Ke ◽  
Yuheng Wang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Drug Resistance ◽  
Therapeutic Efficacy ◽  
Cisplatin Resistance ◽  
Clinical Applications ◽  
Lung Cancers ◽  
Resistance Reversal ◽  
Tumor Acidity ◽  
Stress Amplification ◽  
Novel Strategy

Drug resistance of cisplatin significantly limits its therapeutic efficacy in clinical applications against a variety of cancers. Herein, we develop a novel strategy to overcome cisplatin drug resistance through sensitizing...

scholarly journals Targeting JUN, CEBPB, and HDAC3: A Novel Strategy to Overcome Drug Resistance in Hypoxic Glioblastoma

2019 ◽  
Vol 9 ◽  
Author(s):  
Yixing Gao ◽  
Bao Liu ◽  
Lan Feng ◽  
Binda Sun ◽  
Shu He ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Novel Strategy

scholarly journals Label-free quantitative proteomics trends for protein–protein interactions

2013 ◽  
Vol 81 ◽  
pp. 91-101 ◽  
Author(s):  
Stephen Tate ◽  
Brett Larsen ◽  
Ron Bonner ◽  
Anne-Claude Gingras
Keyword(s):  
Protein Interactions ◽  
Quantitative Proteomics ◽  
Label Free ◽  
Protein Protein Interactions

A novel strategy for quantitative proteomics using isotope-coded protein labels

PROTEOMICS ◽  
2005 ◽  
Vol 5 (1) ◽  
pp. 4-15 ◽  
Author(s):  
Alexander Schmidt ◽  
Josef Kellermann ◽  
Friedrich Lottspeich
Keyword(s):  
Quantitative Proteomics ◽  
Novel Strategy

A novel strategy for quantitative proteomics using isotope-coded protein labels (vol. 5, Issue 1, pp. 4-15)

PROTEOMICS ◽  
2005 ◽  
Vol 5 (3) ◽  
pp. 826-826 ◽  
Author(s):  
Alexander Schmidt ◽  
Josef Kellermann ◽  
Friedrich Lottspeich
Keyword(s):  
Quantitative Proteomics ◽  
Novel Strategy
Sign in / Sign up

Export Citation Format

Share Document