An unexpected discovery of 1,4-benzoquinone as a lipophilic mediator for toxicity detection in water

The Analyst ◽  
2020 ◽  
Vol 145 (15) ◽  
pp. 5266-5272 ◽  
Author(s):  
Dengbin Yu ◽  
Jiantao Li ◽  
Zhichao Kang ◽  
Ling Liu ◽  
Jingting He ◽  
...  
Keyword(s):  
Single Species ◽  
Risk Assessments ◽  
Ecosystem Assessments ◽  
Toxicological Risk

Since most toxicological risk assessments are based on individual single-species tests, there is uncertainty in extrapolating these results to ecosystem assessments.

Marmosets (Callithrix jacchus) as Useful Species for Toxicological Risk Assessments

1992 ◽  
pp. 347-376 ◽  
Author(s):  
Diether Neubert ◽  
Stephan Klug ◽  
Georg Golor ◽  
Reinhard Neubert ◽  
Annegret Felies
Keyword(s):  
Callithrix Jacchus ◽  
Risk Assessments ◽  
Toxicological Risk

Single- and multi-species toxicity testing with nematodes.

2021 ◽  
pp. 298-322
Author(s):  
Sebastian Höss
Keyword(s):  
Caenorhabditis Elegans ◽  
Test Organism ◽  
Toxicity Testing ◽  
Single Species ◽  
Risk Assessments ◽  
Freshwater Sediments ◽  
Nematode Communities ◽  
Model Ecosystems ◽  
Test Organisms ◽  
Experimental Approaches

Abstract This chapter discusses the utility of nematodes in experimental ecotoxicology, and specifically in the study of freshwaters. Drawing on reports in which nematodes were used as test organisms in single-species tests as well as studies investigating nematode communities in model ecosystems (i.e. microcosms), the suitability of nematode-based experimental approaches in prospective and retrospective risk assessments of chemicals in freshwater sediments is examined. Several examples are presented of the use of Caenorhabditis elegans as a test organism in single-species bioassays, in order to demonstrate the versatility of this nematode for ecotoxicological investigations.

Toxicological Risk Assessments of Iron Oxide Nanocluster- and Gadolinium-Based T1MRI Contrast Agents in Renal Failure Rats

ACS Nano ◽  
2019 ◽  
Vol 13 (6) ◽  
pp. 6801-6812 ◽  
Author(s):  
Qinjie Weng ◽  
Xi Hu ◽  
Jiahuan Zheng ◽  
Fan Xia ◽  
Nan Wang ◽  
...  
Keyword(s):  
Renal Failure ◽  
Iron Oxide ◽  
Contrast Agents ◽  
Risk Assessments ◽  
Toxicological Risk

In vitro assembly of 2-D crystals from partially purified EA1 protein secreted by Bacillus anthracis strain Delta Sterne-1

1994 ◽  
Vol 52 ◽  
pp. 276-277
Author(s):  
Mary Beth Downs ◽  
Wilson Ribot ◽  
Joseph W. Farchaus
Keyword(s):  
Cell Wall ◽  
Molecular Sieves ◽  
Cell Envelope ◽  
Single Species ◽  
Supporting Cell ◽  
Surface Layers ◽  
Rabbit Igg ◽  
In Vitro Assembly ◽  
Covalently Linked

Many bacteria possess surface layers (S-layers) that consist of a two-dimensional protein lattice external to the cell envelope. These S-layer arrays are usually composed of a single species of protein or glycoprotein and are not covalently linked to the underlying cell wall. When removed from the cell, S-layer proteins often reassemble into a lattice identical to that found on the cell, even without supporting cell wall fragments. S-layers exist at the interface between the cell and its environment and probably serve as molecular sieves that exclude destructive macromolecules while allowing passage of small nutrients and secreted proteins. Some S-layers are refractory to ingestion by macrophages and, generally, bacteria are more virulent when S-layers are present.When grown in rich medium under aerobic conditions, B. anthracis strain Delta Sterne-1 secretes large amounts of a proteinaceous extractable antigen 1 (EA1) into the growth medium. Immunocytochemistry with rabbit polyclonal anti-EAl antibody made against the secreted protein and gold-conjugated goat anti-rabbit IgG showed that EAI was localized at the cell surface (fig 1), which suggests its role as an S-layer protein.

Column: Risk Assessments

Polymer News ◽  
2004 ◽  
Vol 29 (7) ◽  
pp. 220-223
Author(s):  
Charles Carraher, Jr.
Keyword(s):  
Risk Assessments
Sign in / Sign up

Export Citation Format

Share Document