In situ multiplex detection of serum exosomal microRNAs using an all-in-one biosensor for breast cancer diagnosis

The Analyst ◽  
2020 ◽  
Vol 145 (9) ◽  
pp. 3289-3296 ◽  
Author(s):  
Huizhen Wang ◽  
Dinggeng He ◽  
Kejing Wan ◽  
Xiaowu Sheng ◽  
Hong Cheng ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Diagnosis ◽  
Simultaneous Detection ◽  
Breast Cancer Diagnosis ◽  
Multiplex Detection ◽  
Strand Displacement

Herein, a simple all-in-one biosensor based on a DNA three-way junction has been constructed for in situ simultaneous detection of multiple miRNAs by competitive strand displacement.

Microfluidic-assisted chromogenic in situ hybridization (MA-CISH) for fast and accurate breast cancer diagnosis

2017 ◽  
Vol 183-184 ◽  
pp. 52-57 ◽  
Author(s):  
Huu Tuan Nguyen ◽  
Léa S. Bernier ◽  
Antoine M. Jean ◽  
Raphaël Trouillon ◽  
Martin A.M. Gijs
Keyword(s):  
Breast Cancer ◽  
In Situ Hybridization ◽  
Cancer Diagnosis ◽  
Breast Cancer Diagnosis ◽  
Chromogenic In Situ Hybridization

A multidisciplinary team approach to efficient breast cancer diagnosis.

2016 ◽  
Vol 34 (7_suppl) ◽  
pp. 88-88
Author(s):  
Mary E. Cianfrocca ◽  
Melissa Shelby ◽  
Shefali Birdi ◽  
Stephanie Costa Byrum ◽  
Julie Annie Yee Billar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Diagnosis ◽  
Multidisciplinary Team ◽  
Carcinoma In Situ ◽  
Value Added ◽  
Breast Cancer Diagnosis ◽  
Cancer Center ◽  
Team Approach ◽  
Multidisciplinary Team Approach

88 Background: System inefficiencies result in delayed breast cancer diagnoses. Inefficiencies include any non-value added steps between symptom onset/imaging abnormality to cancer diagnosis and treatment. Diagnostic delays can lead to more advanced disease and may negatively impact survival. Further, optimizing the efficiency of diagnostic evaluation models can reduce barriers to care and improve patient satisfaction. To achieve these efficiency goals, Banner MD Anderson Cancer Center (BMDACC) instituted the Undiagnosed Breast Clinic (UBC). The UBC expedites patient evaluation through a multidisciplinary diagnostic team of internists, surgeons, pathologists and radiologists. Patients with an abnormality on physical exam or imaging are promptly evaluated by the UBC team and any necessary diagnostic tests are performed. If malignancy is diagnosed, the BMDACC breast team swiftly institutes multidisciplinary care. Methods: We conducted a retrospective chart review of patients seen in the UBC from 12/2012 - 12/2013. We tallied patient demographics, diagnostic data, and treatment information. Results: 177 patients (174 females; 3 males) were identified. Mean age was 54 years (range: 16-91). Patient racial breakdown was 144 (81%) Caucasian; 8 (5%) Black, 6 (3%) Latina, 4 (2%) Asian, and 15 (8%) Other. Malignant diagnoses (invasive carcinoma or ductal carcinoma in situ) were found in 28 patients (16%), and high-risk lesions (atypia or lobular carcinoma in situ) were found in 8 patients (5%). Of the 46 patients who underwent needle biopsy as part of the UBC evaluation, 28 (61%) underwent biopsy the same day as the initial visit. An additional 5 patients (11%) underwent biopsy the next day.Genetics consults were obtained in 11 patients (6%). Of these 11 patients, one tested positive for BRCA 1 and one for BRCA2. Conclusions: A multidisciplinary team approach to breast cancer diagnosis is feasible. The resultant evaluation eliminates non-value added steps in the patients’ workup, thereby expediting time from presentation to diagnosis and, if needed, treatment.

Physical Activity and Survival Subsequent to Metastatic Breast Cancer Diagnosis

2010 ◽  
Author(s):  
Susan Sharp ◽  
Ashleigh Golden ◽  
Cheryl Koopman ◽  
Eric Neri ◽  
David Spiegel
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Metastatic Breast Cancer ◽  
Cancer Diagnosis ◽  
Metastatic Breast ◽  
Breast Cancer Diagnosis

The significance of patient’s knowledge and behavior after breast cancer diagnosis

2019 ◽  
Vol 3 (48) ◽  
pp. 7
Author(s):  
Alina Oana Rusu-Moldovan ◽  
Maria Iuliana Gruia ◽  
Dan Mihu
Keyword(s):  
Breast Cancer ◽  
Cancer Diagnosis ◽  
Breast Cancer Diagnosis ◽  
And Behavior
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