Selenium–nitrogen bond formation by ring expansion: synthesis of the 1,4,2-diselenazine ring system, fragmentation to a 1,2-diselenete and reactions to yield 1,4-diselenin derivatives

1996 ◽  
pp. 2375-2376 ◽  
Author(s):  
Shimon Yoshida ◽  
Martin R. Bryce ◽  
Antony Chesney
Keyword(s):  
Bond Formation ◽  
Ring Expansion ◽  
Ring System ◽  
Nitrogen Bond

ChemInform Abstract: Carbon-Nitrogen Bond Formation Catalyzed by Metalloporphyrins

ChemInform ◽  
2010 ◽  
Vol 32 (23) ◽  
pp. no-no
Author(s):  
Sergio Cenini ◽  
Emma Gallo ◽  
Andrea Penoni
Keyword(s):  
Bond Formation ◽  
Nitrogen Bond

A Valuable Synthesis of Pyrrolo[1,2-a]quinoxalines, Indolo[1,2-a]quinoxalines and their Aza-Analogues by Palladium-Catalyzed Intramolecular Carbon-Nitrogen Bond Formation

Synthesis ◽  
2005 ◽  
Vol 2005 (17) ◽  
pp. 2881-2886 ◽  
Author(s):  
Egle M. Beccalli ◽  
Giorgio Abbiati ◽  
Gianluigi Broggini ◽  
Giuseppe Paladino ◽  
Elisabetta Rossi
Keyword(s):  
Bond Formation ◽  
Palladium Catalyzed ◽  
Nitrogen Bond

Laccase-catalyzed carbon–nitrogen bond formation: coupling and derivatization of unprotected l-phenylalanine with different para-hydroquinones

Amino Acids ◽  
2008 ◽  
Vol 37 (2) ◽  
pp. 315-321 ◽  
Author(s):  
V. Hahn ◽  
A. Mikolasch ◽  
K. Manda ◽  
D. Gördes ◽  
K. Thurow ◽  
...  
Keyword(s):  
Bond Formation ◽  
Nitrogen Bond

scholarly journals Michael Addition of Imidazole to α, β -Unsaturated Carbonyl/Cyano Compound

2018 ◽  
Vol 5 (1) ◽  
pp. 18-31
Author(s):  
Seetaram Mohapatra ◽  
Nilofar Baral ◽  
Nilima Priyadarsini Mishra ◽  
Pravati Panda ◽  
Sabita Nayak
Keyword(s):  
Organic Chemistry ◽  
Amino Acids ◽  
Anticancer Agents ◽  
Michael Addition ◽  
Addition Reaction ◽  
Bond Formation ◽  
Conjugate Addition ◽  
Michael Addition Reaction ◽  
Cyano Compounds ◽  
Nitrogen Bond

Introduction: Aza-Michael addition is an important reaction for carbon-nitrogen bond formation in synthetic organic chemistry. Expalantion: Conjugate addition of imidazole to α,β-unsaturated carbonyl/cyano compounds provides significant numbers of the biologically and synthetically interesting products, such as β-amino acids and β-lactams, which have attracted great attention for their use as key intermediates of anticancer agents, antibiotics and other drugs. Conclusion: This review addresses most significant method for the synthesis of N-substituted imidazole derivatives following Michael addition reaction of imidazole to α,β-unsaturated carbonyl/cyano compounds using ionic liquid/base/acid/enzyme as catalysts from year 2007-2017.

ChemInform Abstract: BF3·OEt2-Mediated One Pot Synthesis of 10-Indolyldibenzo[b,f]azepine Derivatives via Tandem Ring Expansion and C-C Bond Formation.

ChemInform ◽  
2015 ◽  
Vol 46 (13) ◽  
pp. no-no
Author(s):  
Trimurtulu Kotipalli ◽  
Donala Janreddy ◽  
Veerababurao Kavala ◽  
Chun-Wei Kuo ◽  
Ting-Shen Kuo ◽  
...  
Keyword(s):  
Bond Formation ◽  
Ring Expansion ◽  
One Pot ◽  
One Pot Synthesis

scholarly journals Correction to Nitrogen–Nitrogen Bond Formation via a Substrate-Bound Anion at a Mononuclear Nickel Platform

2018 ◽  
Vol 37 (6) ◽  
pp. 1086-1086 ◽  
Author(s):  
Mikhail D. Kosobokov ◽  
Aaron Sandleben ◽  
Nicolas Vogt ◽  
Axel Klein ◽  
David A. Vicic
Keyword(s):  
Bond Formation ◽  
Nitrogen Bond

Synthetic studies related to mycobactins. III. Approaches to the synthesis of the cobactin ring system

1972 ◽  
Vol 25 (11) ◽  
pp. 2429 ◽  
Author(s):  
DSC Black ◽  
RFC Brown ◽  
AM Wade
Keyword(s):  
Primary Amine ◽  
Ring Expansion ◽  
Hydroxamic Acids ◽  
Ring System ◽  
Ethyl Benzoate ◽  
Yield Reduction ◽  
Similar Reaction ◽  
Oxidation Reactions ◽  
Cyclic Hydroxamic Acids ◽  
Synthetic Studies

The synthesis of several seven-membered cyclic hydroxamic acids has been carried out in low yield. Reduction of diethyl 2-hydroxyiminoheptane-l,7-dioate afforded ethyl 1-hydroxy-7-oxohexahydroazepine-2-carboxylate, together with related acyclic products. The cobactin precursor 3-bromo-1-hydroxyhexahydro-azepin-2-one was obtained by the ring expansion of 2-bromocyclohexanone with benzenesulphonohydroxamic acid and also by the peracid oxidation of 6-bromo-7-ethoxy-3,4,5,6-tetrahydro-2H-azepine. The methyl and cinnamyl imidates of hexanolactam were oxidized by peracid to 1-hydroxyhexahydroazepin-2-one, in addition to the related imino- and nitroso-hexanoic esters. In a similar reaction, 1-hydroxypiperidin-2-one was obtained from 2-methoxy-3,4,5,6-tetrahydropyridine. During the course of these oxidation reactions, the intermediate oxaziridines 7-methoxy-8-oxa-1-azabicyclo[5,1,0]octane and 6-bromo-7-ethoxy-8-oxa-1-azabicyclo[5,1,0]octane were isolated and identified. The peraoid oxidation of ethyl N-cyclohexylbenzimidate yielded cyclohexylhydroxylamine and ethyl benzoate in reasonable yields. This reaction suggests a useful method for the conversion of a primary amine into the related hydroxylamine.

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