Current status and future perspectives of cyclohexadiene-cis-diols in organic synthesis: versatile intermediates in the concise design of natural products

1996 ◽  
pp. 1993 ◽  
Author(s):  
Tomas Hudlicky ◽  
Andrew J. Thorpe
2018 ◽  
Vol 23 (37) ◽  
pp. 5760-5765 ◽  
Author(s):  
Antonio Gambardella ◽  
Angelo Labate ◽  
Laura Mumoli ◽  
Iscia Lopes-Cendes ◽  
Fernando Cendes

2018 ◽  
Vol 15 (2) ◽  
pp. 221-229 ◽  
Author(s):  
Shah Bakhtiar Nasir ◽  
Noorsaadah Abd Rahman ◽  
Chin Fei Chee

Background: The Diels-Alder reaction has been widely utilised in the syntheses of biologically important natural products over the years and continues to greatly impact modern synthetic methodology. Recent discovery of chiral organocatalysts, auxiliaries and ligands in organic synthesis has paved the way for their application in Diels-Alder chemistry with the goal to improve efficiency as well as stereochemistry. Objective: The review focuses on asymmetric syntheses of flavonoid Diels-Alder natural products that utilize chiral ligand-Lewis acid complexes through various illustrative examples. Conclusion: It is clear from the review that a significant amount of research has been done investigating various types of catalysts and chiral ligand-Lewis acid complexes for the enantioselective synthesis of flavonoid Diels-Alder natural products. The results have demonstrated improved yield and enantioselectivity. Much emphasis has been placed on the synthesis but important mechanistic work aimed at understanding the enantioselectivity has also been discussed.


Author(s):  
Giulia Anna Follacchio ◽  
Francesco Monteleone ◽  
Maria Letizia Meggiorini ◽  
Maria Paola Nusiner ◽  
Carlo De Felice ◽  
...  

2019 ◽  
Vol 31 (4) ◽  
pp. 363-371 ◽  
Author(s):  
Shin‐ei Kudo ◽  
Yuichi Mori ◽  
Masashi Misawa ◽  
Kenichi Takeda ◽  
Toyoki Kudo ◽  
...  

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