scholarly journals Environmental distribution of the neurotoxin l-BMAA in Paenibacillus species

2019 ◽  
Vol 8 (6) ◽  
pp. 781-783 ◽  
Author(s):  
Peter B. Nunn ◽  
Geoffrey A. Codd
Keyword(s):  
Amino Acid ◽  
Human Body ◽  
Aquatic Organisms ◽  
American Foulbrood ◽  
Pacific Island ◽  
Environmental Distribution ◽  
The Pacific ◽  
Experimental Approaches ◽  
Diaminopropanoic Acid ◽  
Paenibacillus Species

Abstract The environmental distribution of the neurotoxic amino acid, 3-N-methyl-2,3-diaminopropanoic acid (BMAA), first isolated in 1967, was initially believed to be limited to tropical and subtropical plants of the genus Cycas. The seeds of one such species, which had been used historically on the Pacific island of Guam as a foodstuff, had a reputation for neurotoxicity. Some 40 years later the amino acid was detected in terrestrial and aquatic cyanobacteria and in other aquatic organisms. Overlooked was the discovery of BMAA in peptides of bizarre structure that had been isolated in 1975 from Paenibacillus pulvifaciens during a search for antibiotics. More recently (2014), peptides of similar structure were isolated from Paenibacillus larvae; this organism is causative of American Foulbrood, a lethal disease of honeybee colonies. These are interesting chemical and environmental observations, but knowledge of the bacterial distribution of BMAA is limited to just these two species of Paenibacillus, while more than 200 Paenibacillus spp. are known. Paenibacillus spp. are ever present naturally in the environment and are used agriculturally; recent research reports that some species infect human foods – including cow's milk – and have been isolated from human body fluids. We wish to stimulate interest in the environmental distribution of the neurotoxic BMAA in Paenibacillus spp. by drawing together previously isolated streams of research and by proposing experimental approaches by which this matter might be resolved.

Before the summit: News media framing, scripts and the flag-raising at Iwo Jima

2021 ◽  
pp. 175063522199094
Author(s):  
Matthew Pressman ◽  
James J Kimble
Keyword(s):  
World War Ii ◽  
Government Policy ◽  
News Media ◽  
News Coverage ◽  
Media Framing ◽  
Pacific Island ◽  
World War ◽  
The Pacific ◽  
Cognitive Scripts ◽  
New Interpretation

Drawing upon media framing theory and the concept of cognitive scripts, this article provides a new interpretation of the context in which the famous World War II photograph ‘Raising the Flag on Iwo Jima’ appeared. This interpretation is based primarily on an examination of American newspaper and newsreel coverage from the Pacific island battles prior to Iwo Jima. The coverage – especially the pictorial coverage – often followed a three-step sequence that showed US forces proceeding from a landing to a series of skirmishes, then culminating with a flag-raising image. This created a predictable cognitive script. That script, combined with other framing devices found in the news coverage (such as metaphors and catchphrases), conveyed the misleading message that the Allies’ final victory over Japan was imminent in early 1945. The Iwo Jima photo drove home that message more emphatically than anything else. This circumstance had profound implications for government policy at the time and, in retrospect, it illustrates the potency of media framing – particularly in times of crisis or war.

“We Are Our History”: Reviewing the History of Education in Hawaiʻi and Oceania

2020 ◽  
Vol 60 (4) ◽  
pp. 632-643
Author(s):  
Derek Taira
Keyword(s):  
Pacific Islands ◽  
History Of Education ◽  
Oral Traditions ◽  
Pacific Island ◽  
The Pacific ◽  
History Of ◽  
National Boundaries ◽  
Pacific Island Nations

There is a “world of difference,” anthropologist Epeli Hauʻofa argued, “between viewing the Pacific as ‘islands in a far sea’ and as ‘a sea of islands.’” The distinction between both perspectives, he explained, is exemplified in the two names used for the region: Pacific Islands and Oceania. The former represents a colonial vision produced by white “continental men” emphasizing the smallness and remoteness of “dry surfaces in a vast ocean far from centers of power.” This understanding has produced and sustained an “economistic and geographic deterministic view” emphasizing Pacific Island nations as “too small, too poor, and too isolated” to take care of themselves. The latter, in contrast, denotes a grand space inhabited by brave and resourceful people whose myths, legends, oral traditions, and cosmologies reveal how they did not conceive of themselves in such “microscopic proportions.” Rather, Oceanic peoples have for over two millennia viewed the sea as a “large world” where peoples, goods, and cultures moved and mingled unhindered by fixed national boundaries.

POPULATION TRENDS OF THE FOREST BIRD COMMUNITY ON THE PACIFIC ISLAND OF ROTA, MARIANA ISLANDS

The Condor ◽  
2008 ◽  
Vol 110 (3) ◽  
pp. 421-427 ◽  
Author(s):  
ARJUN AMAR ◽  
FRED AMIDON ◽  
BEATRIZ ARROYO ◽  
JACOB A. ESSELSTYN ◽  
ANN P. MARSHALL
Keyword(s):  
Bird Community ◽  
Population Trends ◽  
Pacific Island ◽  
Mariana Islands ◽  
Forest Bird ◽  
The Pacific

scholarly journals Pacific Regionalism: Historical Anachronism, or Pathway to Future Development?

2021 ◽  
Author(s):  
◽  
Elspeth Davidson
Keyword(s):  
Pacific Islands ◽  
Good Governance ◽  
Positive Development ◽  
Small Island ◽  
Pacific Island ◽  
Diverse Range ◽  
Pacific People ◽  
Island States ◽  
The Pacific ◽  
Regional Organisations

<p>This study looks at the relevance of regional organisations in the Pacific Island region. It analyses the history of the key regional organisations: the Secretariat of the Pacific Community (SPC) and the Pacific Islands Forum Secretariat (PIFS). Since their establishment, there has been extensive criticism of the work of these organisations. This study tests and analyses the issue of legitimacy within supra-national organisations, and questions whether regionalism in the Pacific is an anachronism of the past.  In the Pacific, regionalism puts out a compelling argument for its existence. Throughout the region, small island developing states are spread across the world’s largest ocean. Pacific Island states face many challenges, including: small economies, geographical disadvantages, vulnerability to climate change, varying availability to resources and a diverse range of cultures and languages. Regionalism provides a chance for these island states to influence world policy, build capacity in the region, promote good governance, maintain peaceful neighbourly relations, and create positive development outcomes.  The methodology uses qualitative research of document analysis and semi-structured interviews with key informants. The research claims a social constructivist epistemology and uses an inductive conceptual framework in order to find solutions to the complex challenges of Pacific regionalism.  It was found that regional organisations need to increase their transparency in order to enhance their legitimacy. They need provide a clearer evidence base, where all Pacific people can recognise and understand the benefit of regional organisations. The organisations need to work strategically to be nimble and reactive to upcoming critical junctures and issues. Council of Regional Organisations in the Pacific (CROP) agencies need to coordinate better amongst themselves, open up communication with all stakeholders and create clearer mandates. In order to promote positive development, all stakeholders and Pacific people need to take ownership of these organisations, and support the Framework for Pacific Regionalism process. This study argues that there is great potential for regionalism in the Pacific, but this will only be possible if the region works collectively to enhance the legitimacy of these organisations.</p>

scholarly journals On the (un-)predictability of a large intragenic fitness landscape

2016 ◽  
Author(s):  
Claudia Bank ◽  
Sebastian Matuszewski ◽  
Ryan T. Hietpas ◽  
Jeffrey D. Jensen
Keyword(s):  
Amino Acid ◽  
Fitness Landscape ◽  
Fitness Landscapes ◽  
Specific Information ◽  
Theoretical Approaches ◽  
Elevated Salinity ◽  
Theoretical Predictions ◽  
Experimental Approaches ◽  
Deterministic Processes ◽  
Negative Epistasis

AbstractThe study of fitness landscapes, which aims at mapping genotypes to fitness, is receiving ever-increasing attention. Novel experimental approaches combined with NGS methods enable accurate and extensive studies of the fitness effects of mutations – allowing us to test theoretical predictions and improve our understanding of the shape of the true underlying fitness landscape, and its implications for the predictability and repeatability of evolution.Here, we present a uniquely large multi-allelic fitness landscape comprised of 640 engineered mutants that represent all possible combinations of 13 amino-acid changing mutations at six sites in the heat-shock protein Hsp90 in Saccharomyces cerevisiae under elevated salinity. Despite a prevalent pattern of negative epistasis in the landscape, we find that the global fitness peak is reached via four positively epistatic mutations. Combining traditional and extending recently proposed theoretical and statistical approaches, we quantify features of the global multi-allelic fitness landscape. Using subsets of the data, we demonstrate that extrapolation beyond a known part of the landscape is difficult owing to both local ruggedness and amino-acid specific epistatic hotspots, and that inference is additionally confounded by the non-random choice of mutations for experimental fitness landscapes.Author SummaryThe study of fitness landscapes is fundamentally concerned with understanding the relative roles of stochastic and deterministic processes in adaptive evolution. Here, the authors present a uniquely large and complete multi-allelic intragenic fitness landscape of 640 systematically engineered mutations in yeast Hsp90. Using a combination of traditional and recently proposed theoretical approaches, they study the accessibility of the global fitness peak, and the potential for predictability of the fitness landscape topography. They report local ruggedness of the landscape and the existence of epistatic hotspot mutations, which together make extrapolation and hence predictability inherently difficult, if mutation-specific information is not considered.

scholarly journals Multilateral Resource Negotiations Between Weak and Powerful States: The Case of the 1987 United States-Pacific Island Fisheries Treaty

2021 ◽  
Author(s):  
◽  
Sōsefo Fietangata Havea
Keyword(s):  
United States ◽  
Soviet Union ◽  
United States Of America ◽  
Pacific Islands ◽  
The United States ◽  
Pacific Island ◽  
Island States ◽  
The Soviet Union ◽  
The Pacific ◽  
Pacific Island States

<p>On April 2, 1987, the Treaty on Fisheries Between Governments of Certain Pacific Island States and the Government of the United States of America was signed. The signatories to the Fisheries were the 16 members of the South Pacific Forum and the United States of America. After six difficult years of negotiations, the Treaty permitted American fishing vessels to fish in Pacific Islands’ waters in exchange for a substantial access fee. This thesis identifies key aspects of that treaty and examines what it meant from both a theoretical and practical standpoint. How did a collection of small, comparatively weak Pacific states strike a satisfactory deal with the most powerful state on the planet? What did the agreement mean in terms of its political, legal and environmental consequences? As well as looking at the events and negotiations that led to the treaty, this thesis also attempts to discern the key political lessons that flow from this case that might be relevant for the future development of the Pacific island States in the key area of fisheries regulation. The thesis argues that disputes between Pacific nations and the United States over tuna resources and the presence of the Soviet Union in the Pacific region were the two critical factors that led to the adoption of the Treaty. From the United States’ perspective, the Treaty was seen (at the time) as the only viable option if it were to reconsolidate its long and prosperous position in the Pacific region. The US did not want the Soviet Union to capitalize on American fishing disputes with the Pacific islands, and it could not afford for the Soviet Union to establish a strong association with the Pacific islands. The Treaty therefore served three purposes for Washington: (i) it maintained its long friendship with the Pacific islands, (ii) it maintained its fisheries interests in the region, (iii) and it kept the Pacific communist-free. This fusion of US economic and strategic interests gave Pacific Island States a stronger hand in the negotiations than their size and power would have otherwise offered.</p>

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