pH-Responsive metal–organic framework encapsulated gold nanoclusters with modulated release to enhance photodynamic therapy/chemotherapy in breast cancer

2020 ◽  
Vol 8 (8) ◽  
pp. 1739-1747 ◽  
Author(s):  
Luyun Zhang ◽  
Yang Gao ◽  
Sijia Sun ◽  
Zihou Li ◽  
Aiguo Wu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Photodynamic Therapy ◽  
Acidic Medium ◽  
Metal Organic Framework ◽  
Gold Nanoclusters ◽  
Ph Responsive ◽  
Structural Collapse ◽  
Metal Organic ◽  
Organic Framework

AuNCs@MOF-DOX nanocomposites as pH-responsive bi-functional nanoprobes for enhanced synergistic PDT/chemotherapy by the structural collapse of ZIF-8 in acidic medium.

scholarly journals Stepwise collapse of a giant pore metal–organic framework

2021 ◽  
Vol 50 (14) ◽  
pp. 5011-5022 ◽  
Author(s):  
Adam F. Sapnik ◽  
Duncan N. Johnstone ◽  
Sean M. Collins ◽  
Giorgio Divitini ◽  
Alice M. Bumstead ◽  
...  
Keyword(s):  
Distribution Function ◽  
Hierarchical Structure ◽  
Pair Distribution Function ◽  
Function Analysis ◽  
Metal Organic Framework ◽  
Defect Engineering ◽  
Structural Collapse ◽  
The Hierarchical Structure ◽  
Metal Organic ◽  
Organic Framework

Defect engineering is used to augment the porosity of MIL-100. Incorporation of defects leads to structural collapse and ultimately causes amorphisation. Pair distribution function analysis reveals a stepwise collapse of the hierarchical structure.

Rational fabrication of two-photon responsive metal-organic framework for enhanced photodynamic therapy

2021 ◽  
Author(s):  
Xin Yao ◽  
Xinxin Pei ◽  
Bo Li ◽  
Mengqi Lv ◽  
Wen Zhang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Side Effects ◽  
Rational Design ◽  
Metal Organic Framework ◽  
Cancer Treatments ◽  
Two Photon ◽  
Metal Organic ◽  
Organic Framework

Rational design of specific platform which can address the unavoidable side effects of traditional cancer treatments is of great interest. In this sense, herein, an intelligent nanoplatform (ZnL1@MOF-199@FA) with efficient...

scholarly journals Metal-Organic Framework Combined with CaO2 Nanoparticles for Enhanced and Targeted Photodynamic Therapy

2021 ◽  
Author(s):  
Xinran Sun ◽  
Kaixiu Chen ◽  
Ying-Yan Liu ◽  
Guoda Zhang ◽  
Min Shi ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Therapeutic Approach ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Targeted Photodynamic Therapy ◽  
Organic Framework

Photodynamic therapy (PDT) has been rapidly developing an effective therapeutic approach in clinical. However, hypoxia seriously limits the effectiveness of PDT. Here, we report a porphyrinic based metal-organic framework combined...

Porphyrin‐Based Metal−Organic Framework Compounds as Promising Nanomedicines in Photodynamic Therapy

ChemMedChem ◽  
2020 ◽  
Vol 15 (19) ◽  
pp. 1766-1775
Author(s):  
Wenmei Yu ◽  
Wenqiang Zhen ◽  
Qizhi Zhang ◽  
Yanchun Li ◽  
Hongyu Luo ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Framework Compounds ◽  
Organic Framework
Sign in / Sign up

Export Citation Format

Share Document