An efficient strategy for circulating tumor cell detection: surface-enhanced Raman spectroscopy

2020 ◽  
Vol 8 (16) ◽  
pp. 3316-3326 ◽  
Author(s):  
Jie Lin ◽  
Jianping Zheng ◽  
Aiguo Wu
Keyword(s):  
Raman Spectroscopy ◽  
Tumor Cell ◽  
Tumor Tissue ◽  
Circulating Tumor Cell ◽  
Surface Enhanced Raman Spectroscopy ◽  
Cell Detection ◽  
Circulating Cancer Cells ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Circulating tumor cells (CTCs) are circulating cancer cells that shed from tumor tissue into blood vessels and circulate in the blood to invade other organs, which results in fatal metastases. Surface-enhanced Raman scattering (SERS) has great potentials in CTCs detection.

scholarly journals Asphaltene detection using surface enhanced Raman scattering (SERS)

2015 ◽  
Vol 51 (33) ◽  
pp. 7152-7155 ◽  
Author(s):  
O. O. Alabi ◽  
A. N. F. Edilbi ◽  
C. Brolly ◽  
D. Muirhead ◽  
J. Parnell ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Surface Enhanced Raman Spectroscopy ◽  
Gold Substrate ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Surface enhanced Raman spectroscopy using a gold substrate and excitation at 514 nm can detect sub parts per million quantities of asphaltene and thereby petroleum.

scholarly journals Surface-Enhanced Raman Scattering as an Emerging Characterization and Detection Technique

2012 ◽  
Vol 2012 ◽  
pp. 1-15 ◽  
Author(s):  
Mustafa Culha ◽  
Brian Cullum ◽  
Nickolay Lavrik ◽  
Charles K. Klutse
Keyword(s):  
Raman Spectroscopy ◽  
Molecular Biology ◽  
Rapid Growth ◽  
Scientific Community ◽  
Surface Enhanced Raman Spectroscopy ◽  
Biological Applications ◽  
Sers Substrates ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

While surface-enhanced Raman spectroscopy (SERS) has been attracting a continuously increasing interest of scientific community since its discovery, it has enjoyed a particularly rapid growth in the last decade. Most notable recent advances in SERS include novel technological approaches to SERS substrates and innovative applications of SERS in medicine and molecular biology. While a number of excellent reviews devoted to SERS appeared in the literature over the last two decades, we will focus this paper more specifically on several promising trends that have been highlighted less frequently. In particular, we will briefly overview strategies in designing and fabricating SERS substrates using deterministic patterning and then cover most recent biological applications of SERS.

Fabrication of Raspberry-Like Gold Nanoparticles and their Applications in Surface-Enhanced Raman Spectroscopy and Catalysis

2014 ◽  
Vol 881-883 ◽  
pp. 952-955
Author(s):  
Chun Rong Wang ◽  
Xian Zai Yan ◽  
Lili Yu ◽  
Jian Dan Li
Keyword(s):  
Methylene Blue ◽  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Ascorbic Acid ◽  
Surface Enhanced Raman Spectroscopy ◽  
Methanol Solution ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
High Yields

The raspberry-like gold nanoparticles were synthesized with high yields following reduction with hydrochloroauric acid and peptide (Boc-Leu-Aib-Trp-OH) in methanol solution. Peptide acted as reducing agent. The prepared raspberry-like gold nanoparticles are effective application for surface-enhanced Raman scattering in ascorbic acid (Vc). Here, we also demonstrate the effective catalysts of raspberry-like gold nanoparticles for the activation and reduction of methylene blue in the presence of NaBH4.

Fabrication of lipophilic gold nanoparticles for studying lipids by surface enhanced Raman spectroscopy (SERS)

The Analyst ◽  
2014 ◽  
Vol 139 (13) ◽  
pp. 3352-3355 ◽  
Author(s):  
Michael Driver ◽  
Yue Li ◽  
Jinkai Zheng ◽  
Eric Decker ◽  
David Julian McClements ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Surface Enhanced Raman Spectroscopy ◽  
Fabrication Method ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

A simple fabrication method for preparing lipophilic gold nanoparticles (AuNPs) suitable for use as substrates in surface-enhanced Raman scattering (SERS) applications of lipids was developed.

Surface-enhanced Raman scattering on aluminum using near infrared and visible excitation

2014 ◽  
Vol 50 (28) ◽  
pp. 3744-3746 ◽  
Author(s):  
Klaus Bo Mogensen ◽  
Marina Gühlke ◽  
Janina Kneipp ◽  
Shima Kadkhodazadeh ◽  
Jakob B. Wagner ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Near Infrared ◽  
Surface Enhanced Raman Spectroscopy ◽  
Infrared Range ◽  
Support Surface ◽  
Aluminum Films ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Near Infrared Range

Discontinuous nanostructured aluminum films can support surface-enhanced Raman spectroscopy using excitation in the near infrared range.

Surface Enhanced Raman Spectroscopy Detection of Crystal Violet Based on an Excellent Silver Nanoparticles/Silicon Pyramid Arrays Structure

2020 ◽  
Vol 15 (11) ◽  
pp. 1321-1326
Author(s):  
Aning Ma ◽  
Wenjing Wei ◽  
Zhongqiang Zhang ◽  
Sichang Peng ◽  
Yurong Wang ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Silver Nanoparticles ◽  
Raman Scattering ◽  
Crystal Violet ◽  
Surface Enhanced Raman Scattering ◽  
Surface Enhanced Raman Spectroscopy ◽  
Label Free ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

An efficient surface-enhanced Raman scattering substrate based on silver nanoparticles/silicon pyramid arrays structure is theoretically investigated and experimentally demonstrated. The electric field distributions using finite-element-method are calculated. The surface-enhanced Raman scattering behaviors of sensitivity, uniformity and stability are emphatically discussed and compared by the detection of crystal violet. These theoretical and experimental results reveal that the silver nanoparticles/silicon pyramid arrays substrate is expected to be an effective surface-enhanced Raman scattering platform for label-free sensitive surfaceenhanced Raman spectroscopy detection in areas of biotechnology, medicine and food safety.

An ink-jet printed, surface enhanced Raman scattering paper for food screening

RSC Advances ◽  
2014 ◽  
Vol 4 (76) ◽  
pp. 40487-40493 ◽  
Author(s):  
Wei-Ju Liao ◽  
Pradip Kumar Roy ◽  
Surojit Chattopadhyay
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Ink Jet ◽  
Surface Enhanced Raman ◽  
Jet Printing ◽  
Enhanced Raman Scattering

A surface enhanced Raman spectroscopy active strip, with gold nanoparticles, is developed on paper by ink-jet printing for toxic screening.

Surface-Enhanced Raman Spectroscopy of Lipids on Silver Microprobes

1998 ◽  
Vol 52 (2) ◽  
pp. 265-269 ◽  
Author(s):  
Millicent K. Weldon ◽  
Valentin R. Zhelyaskov ◽  
Michael D. Morris
Keyword(s):  
Fatty Acids ◽  
Raman Spectroscopy ◽  
Spatial Distribution ◽  
Sebaceous Gland ◽  
Surface Enhanced Raman Spectroscopy ◽  
Long Chain Fatty Acids ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Long Chain

The surface-enhanced Raman scattering (SERS) spectra of model sebaceous gland secretions and their bacterially generated fatty acids are described. Long-chain fatty acids, their parent triglycerides, and long-chain hydrocarbons have characteristic SERS signatures that make them readily resolvable in heterogeneous mixtures. Silicon-substrate silver microprobes are shown to be useful for studying the spatial distribution of lipids and their corresponding fatty acids in nanoflow rate systems.

ZnO oxide films for ultrasensitive, rapid, and label-free detection of neopterin by surface-enhanced Raman spectroscopy

The Analyst ◽  
2015 ◽  
Vol 140 (15) ◽  
pp. 5090-5098 ◽  
Author(s):  
Agnieszka Kamińska ◽  
Aneta Aniela Kowalska ◽  
Dmytro Snigurenko ◽  
Elżbieta Guziewicz ◽  
Janusz Lewiński ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Low Cost ◽  
Surface Enhanced Raman Spectroscopy ◽  
Label Free ◽  
Sers Substrates ◽  
Label Free Detection ◽  
Surface Enhanced ◽  
Cost Surface ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Efficient and low-cost surface-enhanced Raman scattering (SERS) substrates based on Au coated zinc oxide layers for the detection of neopterin were prepared.

scholarly journals Gold nanodome-patterned microchips for intracellular surface-enhanced Raman spectroscopy

The Analyst ◽  
2015 ◽  
Vol 140 (24) ◽  
pp. 8080-8087 ◽  
Author(s):  
Pieter C. Wuytens ◽  
Ananth Z. Subramanian ◽  
Winnok H. De Vos ◽  
Andre G. Skirtach ◽  
Roel Baets
Keyword(s):  
Raman Spectroscopy ◽  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Surface Enhanced Raman Spectroscopy ◽  
Living Cells ◽  
Top Down ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Top-down patterned gold nanodome microchips are taken up by living cells and serve as a uniform and reproducible sensor for intracellular surface-enhanced Raman scattering.

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