Interfacial interaction of anesthetic lidocaine and mesoporous silica nanoparticles in aqueous solutions and its release properties

2019 ◽  
Vol 7 (44) ◽  
pp. 7026-7032 ◽  
Author(s):  
Yu Sato ◽  
Toshiyuki Ikoma ◽  
Ryo Wakita ◽  
Haruhisa Fukayama
Keyword(s):  
Mesoporous Silica ◽  
Aqueous Solutions ◽  
Silica Nanoparticles ◽  
Electrostatic Interaction ◽  
Mesoporous Silica Nanoparticles ◽  
Interfacial Interaction

The adsorption of lidocaine by electrostatic interaction and the release with or without ions.

scholarly journals Sulfonate-Functionalized Mesoporous Silica Nanoparticles as Carriers for Controlled Herbicide Diquat Dibromide Release through Electrostatic Interaction

2019 ◽  
Vol 20 (6) ◽  
pp. 1330 ◽  
Author(s):  
Yongpan Shan ◽  
Lidong Cao ◽  
Chunli Xu ◽  
Pengyue Zhao ◽  
Chong Cao ◽  
...  
Keyword(s):  
Ionic Strength ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Electrostatic Interaction ◽  
Electrostatic Interactions ◽  
Hydrophobic Interactions ◽  
Mesoporous Silica Nanoparticles ◽  
Epoxy Group ◽  
Herbicidal Activity ◽  
Sulfonate Group

Environmental stimuli-responsive pesticide release is desirable for enhanced efficiency and reduced side effects. In most cases, the loading and release of pesticides mainly depends on hydrophobic interactions and hydrogen bonding. Electrostatic interaction is less investigated as a weapon for achieving high loading content and controlled pesticide release. In this work, negative-charge decorated mesoporous silica nanoparticles (MSNs) were facilely fabricated by introducing sulfonate groups onto MSNs through a post-grafting method. Sulfonate-functionalized MSNs (MSN-SO3) were synthesized by conversion of epoxy group into sulfonate group using a bisulfite ion as a ring opening reagent. Diquat dibromide (DQ), one of the globally used quaternary ammonium herbicides, was efficiently loaded into these negatively charged MSN-SO3 nanoparticles. The loading content was increased to 12.73% compared to those using bare MSNs as carriers (5.31%). The release of DQ from DQ@MSN-SO3 nanoparticles was pH and ionic strength responsive, which was chiefly governed by the electrostatic interactions. Moreover, DQ@MSN-SO3 nanoparticles exhibited good herbicidal activity for the control of Datura stramonium L., and the bioactivity was affected by the ionic strength of the release medium. The strategy of cargo loading and release dependent on the electrostatic interactions could be generally used for charge-carrying pesticides using carriers possessing opposite charges to mitigate the potential negative impacts on the environment.

scholarly journals DNA-Capped Mesoporous Silica Nanoparticles as an Ion-Responsive Release System to Determine the Presence of Mercury in Aqueous Solutions

2012 ◽  
Vol 84 (4) ◽  
pp. 1956-1962 ◽  
Author(s):  
Yunfei Zhang ◽  
Quan Yuan ◽  
Tao Chen ◽  
Xiaobing Zhang ◽  
Yan Chen ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Aqueous Solutions ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Release System

Recent Advances in Application of Azobenzenes Grafted on Mesoporous Silica Nanoparticles in Controlled Drug Delivery Systems Using Light as External Stimulus

2020 ◽  
Vol 20 (11) ◽  
pp. 1001-1016
Author(s):  
Sandra Ramírez-Rave ◽  
María Josefa Bernad-Bernad ◽  
Jesús Gracia-Mora ◽  
Anatoly K. Yatsimirsky
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery Systems ◽  
Mesoporous Silica Nanoparticles ◽  
High Surface ◽  
Delivery Systems ◽  
Surface Reactivity ◽  
External Stimulus ◽  
Recent Advances

Hybrid materials based on Mesoporous Silica Nanoparticles (MSN) have attracted plentiful attention due to the versatility of their chemistry, and the field of Drug Delivery Systems (DDS) is not an exception. MSN present desirable biocompatibility, high surface area values, and a well-studied surface reactivity for tailoring a vast diversity of chemical moieties. Particularly important for DDS applications is the use of external stimuli for drug release. In this context, light is an exceptional alternative due to its high degree of spatiotemporal precision and non-invasive character, and a large number of promising DDS based on photoswitchable properties of azobenzenes have been recently reported. This review covers the recent advances in design of DDS using light as an external stimulus mostly based on literature published within last years with an emphasis on usually overlooked underlying chemistry, photophysical properties, and supramolecular complexation of azobenzenes.

Fluorescent spherical mesoporous silica nanoparticles loaded with emodin: Synthesis, cellular uptake and anticancer activity

2021 ◽  
Vol 119 ◽  
pp. 111619
Author(s):  
Paul Jänicke ◽  
Claudia Lennicke ◽  
Annette Meister ◽  
Barbara Seliger ◽  
Ludger A. Wessjohann ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Anticancer Activity ◽  
Silica Nanoparticles ◽  
Cellular Uptake ◽  
Mesoporous Silica Nanoparticles
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