Cancer nanomedicine: focus on recent developments and self-assembled peptide nanocarriers

2019 ◽  
Vol 7 (48) ◽  
pp. 7639-7655 ◽  
Author(s):  
Faisal Raza ◽  
Hajra Zafar ◽  
Xinru You ◽  
Asifullah Khan ◽  
Jun Wu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Diagnosis ◽  
Diagnosis And Treatment ◽  
Cancer Nanomedicine ◽  
Recent Developments ◽  
Self Assembled

The applications of nanoparticulate drug delivery have received abundant interest in the field of cancer diagnosis and treatment.

scholarly journals Controllable Synthesis of Variable-sized Magnetic Nanocrystals Self-assembled into Porous Nanostructures for Enhanced Cancer Chemo-ferroptosis Therapy and MR Imaging

2022 ◽  
Author(s):  
Jiangxiang Xu ◽  
Hanyuan Zhang ◽  
Yifei Zhang ◽  
Xu Zhang ◽  
Teng Wang ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Cancer Diagnosis ◽  
Diagnosis And Treatment ◽  
Controllable Synthesis ◽  
Magnetic Nanocrystals ◽  
Porous Nanostructures ◽  
Self Assembled

Magnetic-based nanomaterials are promising for cancer diagnosis and treatment. Herein, we develop a self-assembled approach for preparation of a porous magnetic nanosystem, DOX/Mn(0.25)-Fe3O4-III NPs, which can simultaneously achieve chemotherapy, ferroptosis...

scholarly journals Advances in the use of nanocarriers for cancer diagnosis and treatment

2016 ◽  
Vol 14 (1) ◽  
pp. 99-103 ◽  
Author(s):  
Débora Braga Vieira ◽  
Lionel Fernel Gamarra
Keyword(s):  
Drug Delivery ◽  
Cancer Diagnosis ◽  
Targeted Drug Delivery ◽  
Drug Delivery Systems ◽  
Surface Engineering ◽  
Diagnosis And Treatment ◽  
Pharmacological Properties ◽  
Clinical Use ◽  
Targeted Drug ◽  
Future Work

ABSTRACT The use of nanocarriers as drug delivery systems for therapeutic or imaging agents can improve the pharmacological properties of commonly used compounds in cancer diagnosis and treatment. Advances in the surface engineering of nanoparticles to accommodate targeting ligands turned nanocarriers attractive candidates for future work involving targeted drug delivery. Although not targeted, several nanocarriers have been approved for clinical use and they are currently used to treat and/or diagnosis various types of cancers. Furthermore, there are several formulations, which are now in various stages of clinical trials. This review examined some approved formulations and discussed the advantages of using nanocarriers in cancer therapy.

Passive cancer targeting with a viral nanoparticle depends on the stage of tumorigenesis

Nanoscale ◽  
2021 ◽  
Author(s):  
Juan Zhang ◽  
Wenjing Zhang ◽  
Mengsi Yang ◽  
Weiwei Zhu ◽  
Ming Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Solid Tumors ◽  
Cancer Diagnosis ◽  
Tumor Targeting ◽  
Diagnosis And Treatment ◽  
Cancer Targeting ◽  
Promising Strategy ◽  
Nanoparticle Design ◽  
Viral Nanoparticle

Tumor targeting with nanoparticles is a promising strategy for cancer diagnosis and treatment, especially drug delivery to solid tumors. Previous studies mainly focused on nanoparticle design to improve their targeting...

Atherosclerosis and Nanomedicine Potential: Current Advances and Future Opportunities

2020 ◽  
Vol 27 (21) ◽  
pp. 3534-3554 ◽  
Author(s):  
Fan Jiang ◽  
Yunqi Zhu ◽  
Changyang Gong ◽  
Xin Wei
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Controlled Drug Delivery ◽  
Vascular Wall ◽  
Arterial Disease ◽  
Diagnosis And Treatment ◽  
Antiinflammatory Therapy ◽  
Limited Efficacy ◽  
Conventional Drug ◽  
Diagnostic Modalities

Atherosclerosis is the leading inducement of cardiovascular diseases, which ranks the first cause of global deaths. It is an arterial disease associated with dyslipidemia and changes in the composition of the vascular wall. Besides invasive surgical strategy, the current conservative clinical treatment for atherosclerosis falls into two categories, lipid regulating-based therapy and antiinflammatory therapy. However, the existing strategies based on conventional drug delivery systems have shown limited efficacy against disease development and plenty of side effects. Nanomedicine has great potential in the development of targeted therapy, controlled drug delivery and release, the design of novel specific drugs and diagnostic modalities, and biocompatible scaffolds with multifunctional characteristics, which has led to an evolution in the diagnosis and treatment of atherosclerosis. This paper will focus on the latest nanomedicine strategies for atherosclerosis diagnosis and treatment as well as discussing the potential therapeutic targets during atherosclerosis progress, which could form the basis of development of novel nanoplatform against atherosclerosis.

Self-Assembled Nanocarriers Based on Amphiphilic Natural Polymers for Anti- Cancer Drug Delivery Applications

2018 ◽  
Vol 23 (35) ◽  
Author(s):  
Sally Sabra ◽  
Mona Abdelmoneem ◽  
Mahmoud Abdelwakil ◽  
Moustafa Taha Mabrouk ◽  
Doaa Anwar ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Drug ◽  
Natural Polymers ◽  
Anti Cancer ◽  
Drug Delivery Applications ◽  
Self Assembled ◽  
Cancer Drug Delivery

Recent Developments of New DNA Origami Nanostructures for Drug Delivery

2015 ◽  
Vol 21 (22) ◽  
pp. 3181-3190 ◽  
Author(s):  
Juan Yan ◽  
Chongya Hu ◽  
Xunwei Liu ◽  
Jian Zhong ◽  
Gang Sun ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Dna Origami ◽  
Recent Developments

Strategies for Conjugation of Biomolecules to Nanoparticles as Tumor Targeting Agents

2019 ◽  
Vol 25 (37) ◽  
pp. 3917-3926
Author(s):  
Sajjad Molavipordanjani ◽  
Seyed Jalal Hosseinimehr
Keyword(s):  
Drug Delivery ◽  
Iron Oxide ◽  
Medical Imaging ◽  
Cancer Diagnosis ◽  
Carbon Nanoparticles ◽  
Tumor Targeting ◽  
Polymeric Nanoparticles ◽  
Inorganic Nanoparticles ◽  
Active Targeting ◽  
Cancer Diagnosis And Therapy

Combination of nanotechnology, biochemistry, chemistry and biotechnology provides the opportunity to design unique nanoparticles for tumor targeting, drug delivery, medical imaging and biosensing. Nanoparticles conjugated with biomolecules such as antibodies, peptides, vitamins and aptamer can resolve current challenges including low accumulation, internalization and retention at the target site in cancer diagnosis and therapy through active targeting. In this review, we focus on different strategies for conjugation of biomolecules to nanoparticles such as inorganic nanoparticles (iron oxide, gold, silica and carbon nanoparticles), liposomes, lipid and polymeric nanoparticles and their application in tumor targeting.

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