A fluorescent molecularly imprinted device for the on-line analysis of AFP in human serum

2019 ◽  
Vol 7 (40) ◽  
pp. 6187-6194
Author(s):  
Run-tian Ma ◽  
Xiao-bo Zhao ◽  
Xiao-yu Sun ◽  
Jia Liu ◽  
Wei Ha ◽  
...  
Keyword(s):  
Human Serum ◽  
Molecular Imprinting ◽  
Alpha Fetoprotein ◽  
Molecularly Imprinted ◽  
Molecular Imprinting Technology ◽  
On Line ◽  
First Time ◽  
Line Analysis ◽  
Analytical Device

A fluorescent analytical device to on-line detect alpha-fetoprotein in human serum was established for the first time by molecular imprinting technology.

Application of Response Surface Methodology to Synthesize Appropriate Molecularly Imprinted Polymer for Diazinon

2014 ◽  
Vol 605 ◽  
pp. 67-70 ◽  
Author(s):  
Mohsen Rahiminezhad ◽  
Seyed Jamaleddin Shahtaheri ◽  
Mohammad Reza Ganjali ◽  
Abbas Rahimi Rahimi Forushani
Keyword(s):  
Molecular Imprinting ◽  
Molecularly Imprinted Polymer ◽  
Binding Sites ◽  
Capillary Electrochromatography ◽  
Template Molecule ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Molecular Imprinting Technology ◽  
Cross Linker

Molecular imprinting technology has become an interesting research area to the preparation of specific sorbent material for environmental and occupational sample preparation techniques (1). In the molecular imprinting technology, specific binding sites have been formed in polymeric matrix, which often have an affinity and selectivity similar to antibody-antigen systems (2). In molecular imprinted technology, functional monomers are arranged in a complementary configuration around a template molecule, then, cross-linker and solvent are also added and the mixture is treated to give a porous material containing nono-sized binding sites. After extraction of the template molecule by washing, vacant imprinted sites will be left in polymer, which are available for rebinding of the template or its structural analogue (3). The stability, convention of preparation and low cost of these materials make them particularly attractive (4). These synthetic materials have been used for capillary electrochromatography (5), chromatography columns (6), sensors (7), and catalyze system (8). Depending on the molecular imprinting approach, different experimental variables such as the type and amounts of functional monomers, porogenic solvent, initiator, monomer to cross-linker ratio, temperature, and etc may alter the properties of the final polymeric materials. In this work, chemometric approach based on Central Composite Design (CCD) was used to design the experiments as well as to find the optimum conditions for preparing appropriate diazinon molecularly imprinted polymer.

scholarly journals Rapid and selective recognition of Vibrio parahaemolyticus assisted by perfluorinated alkoxysilane modified molecularly imprinted polymer film

RSC Advances ◽  
2020 ◽  
Vol 10 (24) ◽  
pp. 14305-14312 ◽  
Author(s):  
Kaiyue Fu ◽  
Huiwen Zhang ◽  
Yuanyuan Guo ◽  
Juan Li ◽  
Heran Nie ◽  
...  
Keyword(s):  
Polymer Film ◽  
Molecular Imprinting ◽  
Molecularly Imprinted Polymer ◽  
Vibrio Parahaemolyticus ◽  
Selective Recognition ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
High Affinity ◽  
Molecular Imprinting Technology

Molecular imprinting technology offers a means of tailor-made materials with high affinity and selectivity for certain analysts.

Molecularly Imprinted Materials: Towards the Next Generation

2002 ◽  
Vol 723 ◽  
Author(s):  
Lei Ye ◽  
Klaus Mosbach ◽  
David A. Spivak ◽  
Martha Sibrian-Vazquez
Keyword(s):  
Molecular Imprinting ◽  
Next Generation ◽  
Polymer Beads ◽  
Molecularly Imprinted ◽  
Molecular Imprinting Technology ◽  
Recent Developments ◽  
Short Presentation

AbstractThis brief overview summarizes some recent developments from our Center for Molecular Imprinting related to the topic of this symposium. After a short presentation of the principle of molecular imprinting and recognition, the use of different materials including hybrids for the formation of the host will be discussed, followed by examples given of different formats used such as small polymer beads. In closing, potential directions for the next generation of molecular imprinting technology will be discussed.

Selective enrichment of proteins for MALDI-TOF MS analysis based on molecular imprinting

2015 ◽  
Vol 51 (17) ◽  
pp. 3541-3544 ◽  
Author(s):  
Wei Wan ◽  
Qiang Han ◽  
Xiaoqiong Zhang ◽  
Yuming Xie ◽  
Jieping Sun ◽  
...  
Keyword(s):  
Molecular Imprinting ◽  
Molecularly Imprinted Polymers ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Maldi Tof Ms ◽  
Selective Enrichment ◽  
Maldi Tof ◽  
Ms Analysis ◽  
First Time ◽  
Tof Ms

Molecularly imprinted polymers were applied for selective enrichment of proteins in MALDI-TOF MS analysis for the first time.

A core–shell CdTe quantum dots molecularly imprinted polymer for recognizing and detecting p-nitrophenol based on computer simulation

RSC Advances ◽  
2015 ◽  
Vol 5 (90) ◽  
pp. 73424-73433 ◽  
Author(s):  
Yingchun Wang ◽  
Ningwei Wang ◽  
Xiaoni Ni ◽  
Qianqian Jiang ◽  
Wenming Yang ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Computer Simulation ◽  
Molecular Imprinting ◽  
Molecularly Imprinted Polymer ◽  
Cdte Quantum Dots ◽  
Core Shell ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Molecular Imprinting Technology

A novel molecular imprinting technology, combined with computer simulation and QDs, was used to detect 4-NP.

Molecularly imprinted polymers’ application in pesticide residue detection

The Analyst ◽  
2018 ◽  
Vol 143 (17) ◽  
pp. 3971-3989 ◽  
Author(s):  
Saqib Farooq ◽  
Jiyun Nie ◽  
Yang Cheng ◽  
Zhen Yan ◽  
Jing Li ◽  
...  
Keyword(s):  
Thermal Stability ◽  
Pesticide Residue ◽  
Molecular Imprinting ◽  
Molecularly Imprinted Polymers ◽  
High Selectivity ◽  
High Sensitivity ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Residue Detection ◽  
Molecular Imprinting Technology

Molecularly imprinted polymers (MIPs) are produced using molecular imprinting technology (MIT) and have specific analyte-binding abilities and unique properties, including chemical and thermal stability, reusability, high selectivity, and high sensitivity.

scholarly journals Fabrication of Magnetic Molecularly Imprinted Beaded Fibers for Rosmarinic Acid

Nanomaterials ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1478
Author(s):  
Engy M. Saad ◽  
Nesrine Abdelrehim El Gohary ◽  
Basma M. El-Shenawy ◽  
Heba Handoussa ◽  
Anke Klingner ◽  
...  
Keyword(s):  
Molecular Imprinting ◽  
Rosmarinic Acid ◽  
In Vitro Release ◽  
Electrospinning Process ◽  
Molecularly Imprinted ◽  
Molecular Imprinting Technology ◽  
Magnetic Microrobots ◽  
Vitro Release ◽  
Central Composite

The present study describes the fabrication of molecularly imprinted (MI) magnetic beaded fibers using electrospinning. Rosmarinic acid was selected as exemplary yet relevant template during molecular imprinting. A “design of experiments” methodology was used for optimizing the electrospinning process. Four factors, i.e., the concentration of the biodegradable polymer (polycaprolactone), the applied voltage, the flow rate, and the collector distance were varied in a central composite design. The production process was then optimized according to the suitability of the beaded fibers during microrobot fabrication, actuation, and drug release. The optimum average fiber diameter of MI beaded fibers was determined at 857 ± 390 nm with an average number of beads at 0.011 ± 0.002 per µm2. In vitro release profiles of the optimized MI beaded fibers revealed a lower burst rate and a more sustained release when compared to control fibers. Magnetic control of the MI beaded fibers was successfully tested by following selected waypoints along a star-shaped predefined trajectory. This study innovatively combines molecular imprinting technology with magnetic microrobots enabling targeted drug delivery systems that offer precise motion control via the magnetic response of microrobots along with selective uptake of a drug into the microrobot using MI beaded fibers in future.

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