scholarly journals Recent advances in gold nanoparticles for biomedical applications: from hybrid structures to multi-functionality

2019 ◽  
Vol 7 (22) ◽  
pp. 3480-3496 ◽  
Author(s):  
Hyeon-Ho Jeong ◽  
Eunjin Choi ◽  
Elizabeth Ellis ◽  
Tung-Chun Lee
Keyword(s):  
Gold Nanoparticles ◽  
Biomedical Applications ◽  
Hybrid Structures ◽  
Recent Advances ◽  
Classification Framework

Hybrid gold nanoparticles for biomedical applications are reviewed in the context of a novel classification framework and illustrated by recent examples.

Recent Advances of Gold Nanoparticles in Biomedical Applications: State of the Art

2018 ◽  
Vol 77 (2) ◽  
pp. 123-137 ◽  
Author(s):  
Negar Sedghi Aminabad ◽  
Masoud Farshbaf ◽  
Abolfazl Akbarzadeh
Keyword(s):  
Gold Nanoparticles ◽  
Biomedical Applications ◽  
State Of The Art ◽  
Recent Advances

Biomedical Applications of Gold Nanoparticles

2018 ◽  
pp. 837-858 ◽  
Author(s):  
Irshad Ahmad Wani
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Optical Properties ◽  
Diagnostic Imaging ◽  
Biomedical Applications ◽  
Recent Advances ◽  
The Subject

Gold nanoparticles are the subject of intense studies due to the exceptional photo-optical properties combined with the biocompatibility and has proved to be a powerful tool in various nanomedicinal applications. This book chapter discusses the recent advances and current challenges facing the biomedical applications of gold nanoparticles of various sizes and shapes. This chapter summarizes the applications of gold nanoparticles in biomedical area including diagnostic imaging, biosensing, drug delivery, and photothermal and photodynamic strategies etc. The key advantages of the gold nanoparticles including their ease of synthesis and functionalization together with biodistribution and toxicity has also been discussed.

Biomedical Applications of Gold Nanoparticles

2017 ◽  
pp. 74-101 ◽  
Author(s):  
Irshad Ahmad Wani
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Optical Properties ◽  
Diagnostic Imaging ◽  
Biomedical Applications ◽  
Recent Advances ◽  
The Subject

Gold nanoparticles are the subject of intense studies due to the exceptional photo-optical properties combined with the biocompatibility and has proved to be a powerful tool in various nanomedicinal applications. This book chapter discusses the recent advances and current challenges facing the biomedical applications of gold nanoparticles of various sizes and shapes. This chapter summarizes the applications of gold nanoparticles in biomedical area including diagnostic imaging, biosensing, drug delivery, and photothermal and photodynamic strategies etc. The key advantages of the gold nanoparticles including their ease of synthesis and functionalization together with biodistribution and toxicity has also been discussed.

Surface-bioengineered Gold Nanoparticles for Biomedical Applications

2018 ◽  
Vol 25 (16) ◽  
pp. 1920-1944 ◽  
Author(s):  
Zhicong Miao ◽  
Zilin Gao ◽  
Ruoxia Chen ◽  
Xiaoqing Yu ◽  
Zhiqiang Su ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Gold Nanoparticles ◽  
Surface Functionalization ◽  
Metallic Nanoparticles ◽  
Biomedical Applications ◽  
Structure Functions ◽  
Functionalized Nanoparticles ◽  
Recent Advances

The conjugation of gold nanoparticles (AuNPs) with biomolecules could create many outstanding biofunctions for the surface-functionalized nanoparticles and extend their biomedical applications. In this review, we summarize the recent advances in the surface bioengineering of AuNPs with biomolecules, such as DNA, proteins, peptides, and biopolymers, in which the details on the structure, functions, and properties of surface- bioengineered AuNPs are discussed. In addition, the surface-biofunctionalization of AuNPs for biomedical applications like biosensing, bioimaging, drug delivery, and tissue engineering are introduced. It is expected that this work will be very helpful for readers to understand the surface functionalization and engineering techniques for various metallic nanoparticles and design novel biomaterials for biomedical applications.

scholarly journals Phosphatidylserine-Gold Nanoparticles (PS-AuNP) Induce Prostate and Breast Cancer Cell Apoptosis

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1094
Author(s):  
Allan Radaic ◽  
Nam E. Joo ◽  
Soo-Hwan Jeong ◽  
Seong-II Yoo ◽  
Nicholas Kotov ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gold Nanoparticles ◽  
Biomedical Applications ◽  
Therapeutic Potential ◽  
Control Treatment ◽  
Track Record ◽  
Males And Females ◽  
Breast And Prostate Cancer ◽  
First Time

Prostate and breast cancer are the current leading causes of new cancer cases in males and females, respectively. Phosphatidylserine (PS) is an essential lipid that mediates macrophage efferocytosis and is dysregulated in tumors. Therefore, developing therapies that selectively restore PS may be a potential therapeutic approach for carcinogenesis. Among the nanomedicine strategies for delivering PS, biocompatible gold nanoparticles (AuNPs) have an extensive track record in biomedical applications. In this study, we synthesized biomimetic phosphatidylserine-caped gold nanoparticles (PS-AuNPs) and tested their anticancer potential in breast and prostate cancer cells in vitro. We found that both cell lines exhibited changes in cell morphology indicative of apoptosis. After evaluating for histone-associated DNA fragments, a hallmark of apoptosis, we found significant increases in DNA fragmentation upon PS-AuNP treatment compared to the control treatment. These findings demonstrate the use of phosphatidylserine coupled with gold nanoparticles as a potential treatment for prostate and breast cancer. To the best of our knowledge, this is the first time that a phosphatidylserine-capped AuNP has been examined for its therapeutic potential in cancer therapy.

Recent Advances of DNA Hydrogels in Biomedical Applications

2021 ◽  
Author(s):  
Huai-Qing Chen ◽  
Wan Yang ◽  
Hua Zuo ◽  
Hua-Wei He ◽  
Ye-Jing Wang
Keyword(s):  
Biomedical Applications ◽  
Recent Advances ◽  
Dna Hydrogels
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