An injectable nanocomposite hydrogel co-constructed with gold nanorods and paclitaxel-loaded nanoparticles for local chemo-photothermal synergetic cancer therapy

2019 ◽  
Vol 7 (16) ◽  
pp. 2667-2677 ◽  
Author(s):  
Meiyan Liu ◽  
Pingsheng Huang ◽  
Weiwei Wang ◽  
Zujian Feng ◽  
Jianhua Zhang ◽  
...  

A nanocomposite hydrogel, AuNR/PTXmPECTgel, was fabricated for in situ synergetic chemotherapy and photothermal therapy for tumor inhibition.

2016 ◽  
Vol 18 (23) ◽  
pp. 15619-15624 ◽  
Author(s):  
Aquiles Carattino ◽  
Saumyakanti Khatua ◽  
Michel Orrit

Single gold nanorods exhibit great opportunities for bio-sensing, enhanced spectroscopies and photothermal therapy. We show how to red-shift the plasmon resonance of single nanorods controllably.


2017 ◽  
Vol 53 (01) ◽  
pp. 036-040
Author(s):  
D. Dash

ABSTRACTWe have employed unique properties of carbon-based as well as metallic nanomaterials to develop diagnostic / therapeutic devices targeted against thrombotic disorders. We have designed a novel graphene-based biosensor that can detect individuals with high coronary risk. Further, we describe an innovative strategy to ablate pathological thrombus in situ employing near-infrared laser-irradiated gold nanorods (photothermal therapy).


Nanomaterials ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 2149
Author(s):  
Thabang C. Lebepe ◽  
Sundararajan Parani ◽  
Oluwatobi S. Oluwafemi

The application of gold nanorods (AuNRs) and graphene oxide (GO) has been widely studied due to their unique properties. Although each material has its own challenges, their combination produces an exceptional material for many applications such as sensor, therapeutics, and many others. This review covers the progress made so far in the synthesis and application of GO-coated AuNRs (GO–AuNRs). Initially, it highlights different methods of synthesizing AuNRs and GO followed by two approaches (ex situ and in situ approaches) of coating AuNRs with GO. In addition, the properties of GO–AuNRs composite such as biocompatibility, photothermal profiling, and their various applications, which include photothermal therapy, theranostic, sensor, and other applications of GO–AuNRs are also discussed. The review concludes with challenges associated with GO–AuNRs and future perspectives.


2017 ◽  
Vol 5 (35) ◽  
pp. 7393-7402 ◽  
Author(s):  
Kang Dou ◽  
Wenwen Zhu ◽  
Yousheng Zou ◽  
Yu Gu ◽  
Jubin Li ◽  
...  

The synthesized MoO2 nanocrystals exhibit excellent photothermal temperature elevation of about 37.5 °C under 808 nm laser irradiation, and tumor inhibition effects with an inhibition rate of up to 80.45% as a photothermal therapy agent against 4T1 cancer cells.


2019 ◽  
Vol 7 (28) ◽  
pp. 4393-4401 ◽  
Author(s):  
Lina Sun ◽  
Ying Chen ◽  
Fei Gong ◽  
Qian Dang ◽  
Guangzhen Xiang ◽  
...  

Photothermal therapy (PTT) in the first near-infrared (NIR-I) window has made great progress in the treatment of solid tumors, while only a few PTT agents in the second NIR (NIR-II) region have been studied.


ACS Nano ◽  
2016 ◽  
Vol 10 (2) ◽  
pp. 2375-2385 ◽  
Author(s):  
Yanlei Liu ◽  
Meng Yang ◽  
Jingpu Zhang ◽  
Xiao Zhi ◽  
Chao Li ◽  
...  

Nanoscale ◽  
2021 ◽  
Author(s):  
Jinsong Xiong ◽  
Qinghuan Bian ◽  
Shuijin Lei ◽  
Yatian Deng ◽  
Kehan Zhao ◽  
...  

Near-infrared (NIR) light induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in the photothermal therapy...


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