A non-enzymatic glucose sensor based on a CoNi2Se4/rGO nanocomposite with ultrahigh sensitivity at low working potential

2019 ◽  
Vol 7 (14) ◽  
pp. 2338-2348 ◽  
Author(s):  
Bahareh Golrokh Amin ◽  
Jahangir Masud ◽  
Manashi Nath

A CoNi2Se4–rGO nanocomposite fabricated on Ni foam shows excellent efficiency for non-enzymatic glucose sensing at low applied potential.

2017 ◽  
Vol 5 (28) ◽  
pp. 5549-5555 ◽  
Author(s):  
Li Zhang ◽  
Yaru Ding ◽  
Ranran Li ◽  
Chen Ye ◽  
Guangyu Zhao ◽  
...  

Uniform and compact porous Ni@C nanosheet membranes on Ni foam showing remarkable electrocatalytic activity for non-enzymatic glucose sensing.


RSC Advances ◽  
2019 ◽  
Vol 9 (21) ◽  
pp. 12134-12145 ◽  
Author(s):  
Wenyi Wu ◽  
Fengjuan Miao ◽  
Bairui Tao ◽  
Yu Zang ◽  
Lei Zhu ◽  
...  

A self-powered nonenzymatic glucose sensor electrode boasts the advantages of both a glucose sensor and fuel cell.


RSC Advances ◽  
2021 ◽  
Vol 11 (31) ◽  
pp. 18994-18999
Author(s):  
Linzhi Li ◽  
Tianzeng Huang ◽  
Saijun He ◽  
Xing Liu ◽  
Qi Chen ◽  
...  

The fabrication process of the nonenzyme glucose sensing based Cu2+–Cu+/biochar.


1997 ◽  
Vol 8 (7) ◽  
pp. 1293-1304 ◽  
Author(s):  
H Jiang ◽  
I Medintz ◽  
C A Michels

Glucose is a global metabolic regulator in Saccharomyces. It controls the expression of many genes involved in carbohydrate utilization at the level of transcription, and it induces the inactivation of several enzymes by a posttranslational mechanism. SNF3, RGT2, GRR1 and RGT1 are known to be involved in glucose regulation of transcription. We tested the roles of these genes in glucose-induced inactivation of maltose permease. Our results suggest that at least two signaling pathways are used to monitor glucose levels. One pathway requires glucose sensor transcript and the second pathway is independent of glucose transport. Rgt2p, which along with Snf3p monitors extracellular glucose levels, appears to be the glucose sensor for the glucose-transport-independent pathway. Transmission of the Rgt2p-dependent signal requires Grr1p. RGT2 and GRR1 also play a role in regulating the expression of the HXT genes, which appear to be the upstream components of the glucose-transport-dependent pathway regulating maltose permease inactivation. RGT2-1, which was identified as a dominant mutation causing constitutive expression of several HXT genes, causes constitutive proteolysis of maltose permease, that is, in the absence of glucose. A model of these glucose sensing/signaling pathways is presented.


Nanomaterials ◽  
2022 ◽  
Vol 12 (2) ◽  
pp. 193
Author(s):  
Kamrun Nahar Fatema ◽  
Chang-Sung Lim ◽  
Yin Liu ◽  
Kwang-Youn Cho ◽  
Chong-Hun Jung ◽  
...  

We described the novel nanocomposite of silver doped ZrO2 combined graphene-based mesoporous silica (ZrO2-Ag-G-SiO2,) in bases of low-cost and self-assembly strategy. Synthesized ZrO2-Ag-G-SiO2 were characterized through X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectrometry (EDX), transmission electron microscopy (TEM), high-resolution transmission electron microscopy (HRTEM), Raman spectroscopy, Nitrogen adsorption-desorption isotherms, X-ray photoelectron spectroscopy (XPS), and Diffuse Reflectance Spectroscopy (DRS). The ZrO2-Ag-G-SiO2 as an enzyme-free glucose sensor active material toward coordinate electro-oxidation of glucose was considered through cyclic voltammetry in significant electrolytes, such as phosphate buffer (PBS) at pH 7.4 and commercial urine. Utilizing ZrO2-Ag-G-SiO2, glucose detecting may well be finished with effective electrocatalytic performance toward organically important concentrations with the current reaction of 9.0 × 10−3 mAcm−2 and 0.05 mmol/L at the lowest potential of +0.2 V, thus fulfilling the elemental prerequisites for glucose detecting within the urine. Likewise, the ZrO2-Ag-G-SiO2 electrode can be worked for glucose detecting within the interferometer substances (e.g., ascorbic corrosive, lactose, fructose, and starch) in urine at proper pH conditions. Our results highlight the potential usages for qualitative and quantitative electrochemical investigation of glucose through the ZrO2-Ag-G-SiO2 sensor for glucose detecting within the urine concentration.


2020 ◽  
Vol 512 ◽  
pp. 145710 ◽  
Author(s):  
Yuejia Liu ◽  
Wenqiang Zhao ◽  
Xianliang Li ◽  
Jiaqiang Liu ◽  
Yide Han ◽  
...  
Keyword(s):  

NANO ◽  
2019 ◽  
Vol 14 (04) ◽  
pp. 1950045
Author(s):  
Fang Sun ◽  
Lehong Xing ◽  
Xihui Yang ◽  
Hailiang Huang ◽  
Lina Ning

In this study, CuO films with hollow cubic cages were prepared by a facile two-step procedure consisting of electrodeposition synthesis and subsequent direct calcination. First, Cu2O nanocubes were fabricated on ITO substrate through a simple electrodeposition procedure. Then, Cu2O nanocubes were converted to CuO hollow cubic cages without obvious morphological change through direct calcination. The obtained CuO cubic cages serving as active materials illustrated a favorable performance for nonenzymatic glucose sensing with high sensitivity of [Formula: see text]A[Formula: see text]mM[Formula: see text][Formula: see text]cm[Formula: see text] at a low applied potential of 0.50[Formula: see text]V, fast-response time (less than 3[Formula: see text]s), low detection limit of 1.0[Formula: see text][Formula: see text]M and wide linear range up from 2.0[Formula: see text][Formula: see text]M to 1.0[Formula: see text]mM ([Formula: see text]). Moreover, the good selectivity of the CuO cubic cages-based nonenzymatic glucose sensor against electroactive compounds such as ascorbic acid, uric acid and dopamine were also demonstrated. These good features indicate that the as-prepared CuO cubic cages can be used as promising electrode materials, which have a great potential in the development of sensitive and selective nonenzymatic glucose sensors.


1990 ◽  
Vol 259 (5) ◽  
pp. E601-E613 ◽  
Author(s):  
E. P. Widmaier

Glucoprivation represents a model stress in which activation of different stress responses at different ages can be monitored both in vivo and in vitro. Physiological data indicate rat brain contains a liver/pancreas-type glucose sensor, yet no biochemical or immunocytochemical evidence exists for such a sensor. Young rats appear to lack normal hypothalamic glucose-sensing ability and do not show typical secretory patterns of corticotropin-releasing factor, adrenocorticotropic hormone, or corticosterone after experimentally induced glucoprivation. However, they hypersecrete catecholamines and glucagon (compared with adults) and thrive on fuel sources other than glucose that are abundant after birth. High steroid levels during the first 24 h after birth may be critical for inducing gluconeogenic enzymes and promoting differentiation of tissues like pancreas. Neonatal rats also have unique control systems to combat the damaging effects of other stresses like hypoxia; these systems may disappear in adults. Thus the definition of stress may change during development, and the compensatory mechanisms employed to combat stress change from neonatal to adult life and are intricately related to the metabolic needs of the animal.


RSC Advances ◽  
2018 ◽  
Vol 8 (57) ◽  
pp. 32565-32573 ◽  
Author(s):  
Shaojun Yang ◽  
Daliang Liu ◽  
Qing Bo Meng ◽  
Shuyao Wu ◽  
Xi-Ming Song

A novel electrochemical glucose sensor based on methylene blue-reduced graphene oxide nanocomposite was constructed, and the sensor exhibited good glucose oxidase-mimetic electrocatalytic activity towards glucose and practical applicability.


1993 ◽  
Vol 16 (5) ◽  
pp. 268-275 ◽  
Author(s):  
C. Meyerhoff ◽  
F. Bischof ◽  
F.J. Mennel ◽  
F. Sternberg ◽  
E.F. Pfeiffer

For some time the subcutaneous (s.c.) tissue has been the target for continuous glucose measurement. The microdialysis technique permits an extracellular region approach, which has been used for about two decades for measuring various metabolites in dialysates obtained from different body regions. By connecting a s.c. implanted microdialysis probe to a flow chamber of an amperometric glucose sensor, the procedure of glucose sensing was transferred to ex vivo. Using this device it was possible to obtain, for up to 24 hours, s.c. tissue glucose profiles of healthy and diabetic people. The microdialysis theory, the calibration process and other microdialysis technique applications are discussed in this paper. Although the combination of the microdialysis technique and amperometric glucose sensing requires certain technical equipment, the combination of microdialysis and glucose sensor seems to be a promising approach to a continuously functioning glucose sensing system.


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