Enhanced hyperthermic properties of biocompatible zinc ferrite nanoparticles with a charged polysaccharide coating

2019 ◽  
Vol 7 (18) ◽  
pp. 2962-2973 ◽  
Author(s):  
Dorota Lachowicz ◽  
Weronika Górka ◽  
Angelika Kmita ◽  
Andrzej Bernasik ◽  
Jan Żukrowski ◽  
...  

Zinc doping of superparamagnetic iron oxide nanoparticles coated with an ionic derivative of chitosan significantly improves their properties for magnetic hyperthermia.

2014 ◽  
Vol 802 ◽  
pp. 535-539 ◽  
Author(s):  
Fernanda A. Sampaio da Silva ◽  
Edwin E.G. Rojas ◽  
Sérgio Romero ◽  
Marcos Flávio de Campos

Nowadays, superparamagnetic iron oxide nanoparticles are an important tool for cancer treatment, such as magnetic hyperthermia. The goal is heating diseased tissue and then tumor cells are destroyed. Magnetic nanoparticles are promising mainly because they have specific ability to reduce side effects. However, forin vivoapplications, nanoparticles need to be coated by a biocompatible material. In this work, nanoparticles are coated by PEG (biocompatible polymer). Samples were produced by coprecipitation process. Information about particle size, magnetic properties and crystallinity were obtained.


2020 ◽  
Vol 10 (20) ◽  
pp. 7322 ◽  
Author(s):  
Sebastjan Nemec ◽  
Slavko Kralj ◽  
Claire Wilhelm ◽  
Ali Abou-Hassan ◽  
Marie-Pierre Rols ◽  
...  

Photothermal therapy is gathering momentum. In order to assess the effects of the encapsulation of individual or clustered superparamagnetic iron oxide nanoparticles (SPIONs) on nanoparticle light-to-heat conversion, we designed and tested individual and clustered SPIONs encapsulated within a silica shell. Our study compared both photothermia and magnetic hyperthermia, and it involved individual SPIONs as well as silica-encapsulated individual and clustered SPIONs. While, as expected, SPION clustering reduced heat generation in magnetic hyperthermia, the silica shell improved SPION heating in photothermia.


2019 ◽  
Vol 48 (12) ◽  
pp. 3883-3892 ◽  
Author(s):  
Santiago Sánchez-Cabezas ◽  
Roberto Montes-Robles ◽  
Juan Gallo ◽  
Félix Sancenón ◽  
Ramón Martínez-Máñez

Highly-stable ultrasmall superparamagnetic iron oxide nanoparticles (USPIONs) show great potential for the development of theranostic nanodevices.


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