scholarly journals Figure-eight thermal hysteresis of aminomethylenehelicene oligomers with terminal C16 alkyl groups during hetero-double-helix formation

2020 ◽  
Vol 11 (12) ◽  
pp. 3290-3300 ◽  
Author(s):  
Tsukasa Sawato ◽  
Rina Iwamoto ◽  
Masahiko Yamaguchi
Keyword(s):  
Structural Changes ◽  
Thermal Hysteresis ◽  
Double Helix ◽  
Random Coils ◽  
Helix Formation ◽  
Double Helices ◽  
Alkyl Groups

1 : 1 mixtures of aminomethylenehelicene (P)-tetramer and (M)-pentamer with terminal C16 alkyl groups in fluorobenzene showed structural changes between hetero-double-helices B and C and random-coils 2A.

Mercury Electrodes in Nucleic Acid Electrochemistry: Sensitive Analytical Tools and Probes of DNA Structure. A Review

2004 ◽  
Vol 69 (4) ◽  
pp. 715-747 ◽  
Author(s):  
Miroslav Fojta
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Double Helix ◽  
Dna Structure ◽  
Electrochemical Analysis ◽  
Label Free ◽  
Helix Formation ◽  
Mercury Electrodes ◽  
Dna Strand ◽  
Dna Double Helix

This review is devoted to applications of mercury electrodes in the electrochemical analysis of nucleic acids and in studies of DNA structure and interactions. At the mercury electrodes, nucleic acids yield faradaic signals due to redox processes involving adenine, cytosine and guanine residues, and tensammetric signals due to adsorption/desorption of polynucleotide chains at the electrode surface. Some of these signals are highly sensitive to DNA structure, providing information about conformation changes of the DNA double helix, formation of DNA strand breaks as well as covalent or non-covalent DNA interactions with small molecules (including genotoxic agents, drugs, etc.). Measurements at mercury electrodes allow for determination of small quantities of unmodified or electrochemically labeled nucleic acids. DNA-modified mercury electrodes have been used as biodetectors for DNA damaging agents or as detection electrodes in DNA hybridization assays. Mercury film and solid amalgam electrodes possess similar features in the nucleic acid analysis to mercury drop electrodes. On the contrary, intrinsic (label-free) DNA electrochemical responses at other (non-mercury) solid electrodes cannot provide information about small changes of the DNA structure. A review with 188 references.

Simulative Analysis of a Family of DNA Tetrahedrons Produced by Changing the Twisting Number of Each Double Helix

2021 ◽  
Vol 20 (05) ◽  
pp. 529-537
Author(s):  
Hui Bai ◽  
Jia Li ◽  
Heng Zhang ◽  
Shuya Liu
Keyword(s):  
Cross Correlation ◽  
Double Helix ◽  
Dynamics Simulation ◽  
Conformational Variability ◽  
Double Helices ◽  
Dna Tetrahedron ◽  
Entire Trajectory ◽  
Dna Double Helix ◽  
Twist Number ◽  
Insight Into

In this paper, three tetrahedral nanocages, composed of six DNA double helix edges with all having the twist number 1, 2 or 3, have been characterized using classical molecular dynamics simulation to measure the specific structural and conformational features produced by only changing the twisting number of each double helix. The simulation result indicates that three tetrahedral cages are relatively stable and are maintained along the entire trajectory. Each double helix is more inclined to behave as a whole in the 2TD and 3TD cages than in the 1TD cage according to the cross-correlation maps for three nanocages, and also their local motions are more easily induced by the conformational variability of the thymidine linkers due to the increased flexibility of each helix. Hence, the double helices become the important factors on the structural stability of total cages with the DNA twisting number, and also give the signification contributions to the sizes of these cages conferring the larger spaces of the 2TD and 3TD cages than the 1TD cage. Our result provides an insight into which roles the double helix edges play in assembling DNA polyhedron, and also contribute to improving the loading capacity of DNA tetrahedron in drug delivery.

scholarly journals Innenrücktitelbild: Enantiodifferentiating Photodimerization of a 2,6‐Disubstituted Anthracene Assisted by Supramolecular Double‐Helix Formation with Chiral Amines (Angew. Chem. 19/2020)

2020 ◽  
Vol 132 (19) ◽  
pp. 7695-7695
Author(s):  
Akio Urushima ◽  
Daisuke Taura ◽  
Makoto Tanaka ◽  
Naomichi Horimoto ◽  
Junki Tanabe ◽  
...  
Keyword(s):  
Double Helix ◽  
Chiral Amines ◽  
Helix Formation

scholarly journals Base-base mismatches. Thermodynamics of double helix formation for dCA3XA3G + dCT3YT3G (X, Y = A,C,G,D

1985 ◽  
Vol 13 (13) ◽  
pp. 4811-4824 ◽  
Author(s):  
Fareed Aboul-ela ◽  
David Koh ◽  
Ignacio Tinoco ◽  
Francis H. Martin
Keyword(s):  
Double Helix ◽  
Helix Formation

Double Helix Formation of Oligoresorcinols in Water: Thermodynamic and Kinetic Aspects

2009 ◽  
Vol 131 (13) ◽  
pp. 4710-4719 ◽  
Author(s):  
Hidetoshi Goto ◽  
Yoshio Furusho ◽  
Kazuhiro Miwa ◽  
Eiji Yashima
Keyword(s):  
Double Helix ◽  
Helix Formation
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