scholarly journals Hydration of nitriles using a metal–ligand cooperative ruthenium pincer catalyst

2019 ◽  
Vol 10 (45) ◽  
pp. 10647-10652 ◽  
Author(s):  
Beibei Guo ◽  
Johannes G. de Vries ◽  
Edwin Otten
Keyword(s):  
Pincer Complexes ◽  
Aromatic Nitriles ◽  
Mild Conditions ◽  
Metal Ligand

The hydration of a broad range of aliphatic and (hetero)aromatic nitriles is reported via catalysis by metal–ligand cooperative Ru pincer complexes under very mild conditions.

scholarly journals H/D Exchange Under Mild Conditions in Arenes and Unactivated Alkanes with C6D6 and D2O Using Rigid, Electron-rich Iridium PCP Pincer Complexes

2020 ◽  
Author(s):  
Joel D. Smith ◽  
George Durrant ◽  
Daniel Ess ◽  
Warren Piers
Keyword(s):  
Hydrogen Isotope ◽  
Isotope Exchange ◽  
Room Temperature ◽  
Pincer Complexes ◽  
Synthesis And Characterization ◽  
Hydrogen Isotope Exchange ◽  
Mild Conditions ◽  
Highly Active ◽  
Pcp Pincer

<div>The synthesis and characterization of an iridium polyhydride complex (Ir-H4)</div><div>supported by an electron-rich PCP framework is described. This complex readily loses molecular</div><div>hydrogen allowing for rapid room temperature hydrogen isotope exchange (HIE) at the hydridic</div><div>positions and the α-C-H site of the ligand with deuterated solvents such as benzene-d6, toluene-d8</div><div>and THF-d8. The removal of 1-2 equivalents of molecular H2 forms unsaturated iridium carbene</div><div>trihydride (Ir-H3) or monohydride (Ir-H) compounds that are able to create further unsaturation</div><div>by reversibly transferring a hydride to the ligand carbene carbon. These species are highly active</div><div>hydrogen isotope exchange (HIE) catalysts using C6D6 or D2O as deuterium sources for the</div><div>deuteration of a variety of substrates. By modifying conditions to influence the Ir-Hn speciation,</div><div>deuteration levels can range from near exhaustive to selective only for sterically accessible sites.</div><div>Preparative level deuterations of select substrates were performed allowing for procurement of</div><div>>95% deuterated compounds in excellent isolated yields; the catalyst can be regenerated by</div><div>treatment of residues with H2 and is still active for further reactions.</div>

System with Potential Dual Modes of Metal-Ligand Cooperation: Highly Catalytically Active Pyridine-Based PNNH-Ru Pincer Complexes

2014 ◽  
Vol 20 (48) ◽  
pp. 15727-15731 ◽  
Author(s):  
Eran Fogler ◽  
Jai Anand Garg ◽  
Peng Hu ◽  
Gregory Leitus ◽  
Linda J. W. Shimon ◽  
...  
Keyword(s):  
Pincer Complexes ◽  
Catalytically Active ◽  
Metal Ligand

B–H Bond Cleavage via Metal–Ligand Cooperation by Dearomatized Ruthenium Pincer Complexes

2014 ◽  
Vol 33 (14) ◽  
pp. 3716-3726 ◽  
Author(s):  
Aviel Anaby ◽  
Burkhard Butschke ◽  
Yehoshoa Ben-David ◽  
Linda J. W. Shimon ◽  
Gregory Leitus ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Pincer Complexes ◽  
Metal Ligand

O2 Activation by Metal–Ligand Cooperation with IrI PNP Pincer Complexes

2015 ◽  
Vol 137 (14) ◽  
pp. 4634-4637 ◽  
Author(s):  
Moran Feller ◽  
Eyal Ben-Ari ◽  
Yael Diskin-Posner ◽  
Raanan Carmieli ◽  
Lev Weiner ◽  
...  
Keyword(s):  
Pincer Complexes ◽  
O2 Activation ◽  
Metal Ligand

A Facile Synthesis of Functionalised 3H-Pyrroles Promoted by Magnesium and a Catalytic Amount of Iodine

2003 ◽  
Vol 2003 (2) ◽  
pp. 84-86 ◽  
Author(s):  
Xiaoliang Xu ◽  
Yongmin Zhang
Keyword(s):  
Catalytic Amount ◽  
Reductive Coupling ◽  
Facile Synthesis ◽  
Aromatic Nitriles ◽  
Mild Conditions

The intermolecular reductive coupling cyclisation of 3,3-diaryl-2-cyanoacrylonitriles or ethyl 3,3-diaryl-2-cyano-acrylates with aromatic nitriles with magnesium and catalytic iodine in THF afforded 3 H-pyrroles in good yields under neutral and mild conditions.

m-Terphenyl Anchored Palladium Diphosphinite PCP-Pincer Complexes That Promote the Suzuki−Miyaura Reaction Under Mild Conditions

2009 ◽  
Vol 28 (1) ◽  
pp. 188-196 ◽  
Author(s):  
Mark C. Lipke ◽  
Robert A. Woloszynek ◽  
Liqing Ma ◽  
John D. Protasiewicz
Keyword(s):  
Pincer Complexes ◽  
Mild Conditions ◽  
Pcp Pincer

ChemInform Abstract: System with Potential Dual Modes of Metal-Ligand Cooperation: Highly Catalytically Active Pyridine-Based PNNH-Ru Pincer Complexes.

ChemInform ◽  
2015 ◽  
Vol 46 (18) ◽  
pp. no-no
Author(s):  
Eran Fogler ◽  
Jai Anand Garg ◽  
Peng Hu ◽  
Gregory Leitus ◽  
Linda J. W. Shimon ◽  
...  
Keyword(s):  
Pincer Complexes ◽  
Abstract System ◽  
Catalytically Active ◽  
Metal Ligand

scholarly journals Front Cover: Metal‐ligand cooperative activation of HX (X=H, Br, OR) bond on Mn based pincer complexes (14/2021)

2021 ◽  
Vol 647 (14) ◽  
pp. 1397-1397
Author(s):  
Annika M. Krieger ◽  
Vivek Sinha ◽  
Adarsh V. Kalikadien ◽  
Evgeny A. Pidko
Keyword(s):  
Pincer Complexes ◽  
Front Cover ◽  
Cooperative Activation ◽  
Metal Ligand

Achieving Nickel Catalyzed C–S Cross-Coupling under Mild Conditions Using Metal–Ligand Cooperativity

2019 ◽  
Vol 84 (7) ◽  
pp. 4072-4085 ◽  
Author(s):  
Rina Sikari ◽  
Suman Sinha ◽  
Siuli Das ◽  
Anannya Saha ◽  
Gargi Chakraborty ◽  
...  
Keyword(s):  
Cross Coupling ◽  
Mild Conditions ◽  
Metal Ligand

Iron-Promoted Decarboxylation of Arylacetic Acids for the Synthesis of Aromatic Nitriles with Sodium Nitrite as the Nitrogen Source

Synlett ◽  
2020 ◽  
Vol 31 (18) ◽  
pp. 1805-1808 ◽  
Author(s):  
Zhenpeng Shen ◽  
Wenbo Liu ◽  
Xinzhe Tian ◽  
Yun-Lai Ren ◽  
Zhe Zhao
Keyword(s):  
Nitrogen Source ◽  
Functional Groups ◽  
Sodium Nitrite ◽  
Aromatic Nitriles ◽  
Mild Conditions ◽  
Arylacetic Acids

AbstractA new and effective method was developed for the synthesis of aromatic nitriles from arylacetic acids by using NaNO2 as the nitrogen source and Fe(OTf)3 as the promoter at 50 °C. A series of arylacetic acids underwent this transformation to give the targeted products in yields of 51–90%. Because of the mild conditions, the reaction is compatible with a broad range of functional groups, including ester, carboxy, hydroxy, acetamido, halo, nitro, cyano, methoxy, and even highly reactive formyl groups.

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