scholarly journals HAMA: a multiplexed LC-MS/MS assay for specificity profiling of adenylate-forming enzymes

2019 ◽  
Vol 10 (44) ◽  
pp. 10395-10399 ◽  
Author(s):  
Aleksa Stanišić ◽  
Annika Hüsken ◽  
Hajo Kries
Keyword(s):  
Peptide Synthesis ◽  
Nonribosomal Peptide ◽  
Nonribosomal Peptide Synthesis

Adenylation enzymes are engineering targets in ribosomal and nonribosomal peptide synthesis. Through multiplexed LC-MS/MS measurement of hydroxamates, the HAMA assay records specificity profiles of these enzymes in a snap.

Regulation of Nonribosomal Peptide Synthesis as a Mechanism of Antifungal Activity of Probiotics Based on the Bacteria Genera Bacillus and Paenibacillus

2021 ◽  
pp. 111-121
Author(s):  
Nikita Vasilchenko ◽  
Maksim Kulikov ◽  
Varvara Stacenko ◽  
Viktor Pakhomov ◽  
Natalia Kulikova ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Peptide Synthesis ◽  
Nonribosomal Peptide ◽  
Nonribosomal Peptide Synthesis

scholarly journals Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog

2011 ◽  
Vol 108 (10) ◽  
pp. 3912-3917 ◽  
Author(s):  
L. Bonnefond ◽  
T. Arai ◽  
Y. Sakaguchi ◽  
T. Suzuki ◽  
R. Ishitani ◽  
...  
Keyword(s):  
Peptide Synthesis ◽  
Trna Synthetase ◽  
Structural Basis ◽  
Aminoacyl Trna Synthetase ◽  
Nonribosomal Peptide ◽  
Nonribosomal Peptide Synthesis
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