scholarly journals Light-triggered nitric oxide (NO) release from photoresponsive polymersomes for corneal wound healing

2020 ◽  
Vol 11 (1) ◽  
pp. 186-194 ◽  
Author(s):  
Yutian Duan ◽  
Yong Wang ◽  
Xiaohu Li ◽  
Guozhen Zhang ◽  
Guoying Zhang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Wound Healing ◽  
Biomedical Applications ◽  
Corneal Wound Healing ◽  
Corneal Wound ◽  
No Release ◽  
Nitric Oxide Releasing

Nitric oxide-releasing amphiphiles are successfully synthesized through direct polymerization and are engineered as photoresponsive polymersomes for biomedical applications.

scholarly journals Nitric Oxide-Releasing Thermoresponsive Pluronic F127/Alginate Hydrogel for Enhanced Antibacterial Activity and Accelerated Healing of Infected Wounds

Pharmaceutics ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 926
Author(s):  
Jiafu Cao ◽  
Mingzhi Su ◽  
Nurhasni Hasan ◽  
Juho Lee ◽  
Dongmin Kwak ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Wound Healing ◽  
Antibacterial Activity ◽  
Multidrug Resistant ◽  
Pluronic F127 ◽  
Scanning Calorimetry ◽  
No Release ◽  
Infected Wounds ◽  
Nitric Oxide Releasing

Nitric oxide (NO), a highly reactive and lipophilic molecule, is one of the molecules present in the wound environment and implicated as an important regulator in all phases of wound healing. Here, we developed an NO-releasing thermoresponsive hydrogel (GSNO-PL/AL) composed of S-nitrosoglutathione (GSNO), pluronic F127 (PL), and alginate (AL) for the treatment of infected wounds. The GSNO was incorporated into the thermoresponsive PL/AL hydrogel, and differential scanning calorimetry techniques were used for the hydrogel characterization. The hydrogel was assessed by in vitro NO release, antibacterial activity, cytotoxicity, and wound-healing activity. The GSNO-PL/AL hydrogel demonstrated thermal responsiveness and biocompatibility, and it showed sustained NO release for 7 days. It also exhibited potent bactericidal activity against Gram-positive methicillin-resistant Staphylococcus aureus and Gram-negative multidrug-resistant Pseudomonas aeruginosa (MRPA). Moreover, the GSNO-PL/AL treatment of MRPA-infected wounds accelerated healing with a reduced bacterial burden in the wounds. The GSNO-PL/AL hydrogel would be a promising option for the treatment of infected wounds.

Nitric Oxide-Releasing Biomaterials for Biomedical Applications

2016 ◽  
Vol 23 (24) ◽  
pp. 2579-2601 ◽  
Author(s):  
Xin Zhou ◽  
Jimin Zhang ◽  
Guowei Feng ◽  
Jie Shen ◽  
Deling Kong ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Biomedical Applications ◽  
Nitric Oxide Releasing

Corneal Wound Healing in Vitro

1963 ◽  
Vol 56 (5) ◽  
pp. 833-834
Author(s):  
N.A. Wine ◽  
P.K. Basu
Keyword(s):  
Wound Healing ◽  
Corneal Wound Healing ◽  
Corneal Wound

Early Corneal Wound Healing and Inflammatory Responses after Refractive Lenticule Extraction (ReLEx)

2011 ◽  
Vol 52 (9) ◽  
pp. 6213 ◽  
Author(s):  
Andri K. Riau ◽  
Romesh I. Angunawela ◽  
Shyam S. Chaurasia ◽  
Wing S. Lee ◽  
Donald T. Tan ◽  
...  
Keyword(s):  
Wound Healing ◽  
Inflammatory Responses ◽  
Corneal Wound Healing ◽  
Corneal Wound ◽  
Lenticule Extraction

Carboxymethyl chitosan/gelatin/hyaluronic acid blended-membranes as epithelia transplanting scaffold for corneal wound healing

2018 ◽  
Vol 192 ◽  
pp. 240-250 ◽  
Author(s):  
Wenhua Xu ◽  
Zheying Wang ◽  
Ying Liu ◽  
Liping Wang ◽  
Zhiwen Jiang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Hyaluronic Acid ◽  
Carboxymethyl Chitosan ◽  
Corneal Wound Healing ◽  
Corneal Wound

scholarly journals Influence of topical and oral zinc upon corneal wound healing.

1969 ◽  
Vol 53 (6) ◽  
pp. 407-411 ◽  
Author(s):  
G B Hubbard ◽  
B E Herron ◽  
J S Andrews ◽  
J H Elliott
Keyword(s):  
Wound Healing ◽  
Corneal Wound Healing ◽  
Corneal Wound

IL-6 as a corneal wound healing mediator in an in vitro scratch assay

2014 ◽  
Vol 125 ◽  
pp. 183-192 ◽  
Author(s):  
Isabel Arranz-Valsero ◽  
Laura Soriano-Romaní ◽  
Laura García-Posadas ◽  
Antonio López-García ◽  
Yolanda Diebold
Keyword(s):  
Wound Healing ◽  
Scratch Assay ◽  
Corneal Wound Healing ◽  
Corneal Wound

Growth Factor, Cytokine and Protease Interactions During Corneal Wound Healing

2003 ◽  
Vol 1 (2) ◽  
pp. 53-65 ◽  
Author(s):  
Mira Lim ◽  
Michael H. Goldstein ◽  
Sonal Tuli ◽  
Gregory S. Schultz
Keyword(s):  
Wound Healing ◽  
Growth Factor ◽  
Corneal Wound Healing ◽  
Corneal Wound
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