scholarly journals Mass spectrometry-based metabolomics in health and medical science: a systematic review

RSC Advances ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 3092-3104 ◽  
Author(s):  
Xi-wu Zhang ◽  
Qiu-han Li ◽  
Zuo-di Xu ◽  
Jin-jin Dou

Metabolomics is the study of the investigation of small molecules derived from cellular and organism metabolism, which reflects the outcomes of the complex network of biochemical reactions in living systems.

2016 ◽  
Vol 48 (11) ◽  
pp. 1127-1131 ◽  
Author(s):  
Shota Morimoto ◽  
Tomoya Ishikawa ◽  
Kuminori Hyodo ◽  
Takahiro Yamazaki ◽  
Shu Taira ◽  
...  

2016 ◽  
Vol 60 (5) ◽  
pp. 451-458 ◽  
Author(s):  
Lorraine Brennan

Metabolomics is the study of small molecules present in biological samples. In recent years it has become evident that such small molecules, called metabolites, play a key role in the development of disease states. Furthermore, metabolomic applications can reveal information about alterations in certain metabolic pathways under different conditions. Data acquisition in metabolomics is usually performed using nuclear magnetic resonance (NMR)-based approaches or mass spectrometry (MS)-based approaches with a more recent trend including the application of multiple platforms in order to maximise the coverage in terms of metabolites measured. The application of metabolomics is rapidly increasing and the present review will highlight applications in nutrition research.


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