scholarly journals Highly efficient microwave synthesis of rhodanine and 2-thiohydantoin derivatives and determination of relationships between their chemical structures and antibacterial activity

RSC Advances ◽  
2019 ◽  
Vol 9 (67) ◽  
pp. 39367-39380 ◽  
Author(s):  
Waldemar Tejchman ◽  
Bartosz Orwat ◽  
Izabela Korona-Głowniak ◽  
Anna Barbasz ◽  
Ireneusz Kownacki ◽  
...  

An efficient microwave-assisted synthesis of rhodanine and 2-thiohydantoin derivatives, and the correlation between their chemical structure and biological properties is reported.

Author(s):  
Hadis Khodadad ◽  
Farhad Hatamjafari ◽  
Khalil Pourshamsian ◽  
Babak Sadeghi

Aim and Objective: Microwave-assisted condensation of acetophenone 1 and aromatic aldehydes 2 gave chalcone analogs 3, which were cyclized to pyrazole derivatives 6a-f via the reaction with hydrazine hydrate and oxalic acid in the presence of the catalytic amount of acetic acid in ethanol. Materials and Methods: The structural features of the synthesized compounds were characterized by melting point, FT-IR, 1H, 13C NMR and elemental analysis. Results: The antibacterial activities of the synthesized pyrazoles was evaluated against three gram-positive bacteria such as Enterococcus durans, Staphylococcus aureus, Bacillus subtilis and two gram-negative bacteria such as Escherichia coli and Salmonella typhimurium. Conclusion: All the synthesized pyrazoles showed relatively high antibacterial activity against S. aureus strain and none of them demonstrated antibacterial activity against E. coli.


RSC Advances ◽  
2016 ◽  
Vol 6 (57) ◽  
pp. 52058-52066 ◽  
Author(s):  
Seyed Naser Azizi ◽  
Shahram Ghasemi ◽  
Mehrnaz Mikhchian

A new amperometric sensor is prepared based on a Ag doped NaA nanozeolite modified carbon paste electrode (Ag/ACPE) in order to detect hydrogen peroxide (H2O2) in phosphate buffer solution (PBS, pH 7.0).


RSC Advances ◽  
2016 ◽  
Vol 6 (116) ◽  
pp. 115317-115325 ◽  
Author(s):  
Yaru Yan ◽  
Qitong Huang ◽  
Chan Wei ◽  
Shirong Hu ◽  
Hanqiang Zhang ◽  
...  

Cyclic voltammetry of HQ and CC recorded on Nafion/CDs–ZnO/MWCNTs/GCE.


CrystEngComm ◽  
2019 ◽  
Vol 21 (31) ◽  
pp. 4534-4537 ◽  
Author(s):  
Jolie Lucero ◽  
Carla Osuna ◽  
James M. Crawford ◽  
Moises A. Carreon

The microwave synthesis of two prototypical porous organic cages, denoted as CC3 and CC2 is demonstrated.


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